Among the large group of antibiotics used in the treatment of infectious and inflammatory lesions of the bladder, macrolides occupy a worthy place. Azithromycin, used for cystitis, is one of the effective antimicrobial representatives of this group, provided to domestic healthcare by many global pharmaceutical concerns. Its high anti-inflammatory, mucoregulatory and immunomodulatory properties have been confirmed by clinical and experimental studies.
general description
Azithromycin is available in the form of tablets of 3 pieces. in each package. Each tablet contains 250 mg and 500 mg of active ingredient. For a standard course of treatment, one package of the drug is enough.
The antibiotic is quickly absorbed and practically does not cause disruption of the gastrointestinal tract.
The first results of treatment are observed after taking one tablet. Significant improvement is observed three days after the start of treatment. The drug is excreted from the body with bile and urine.
Reviews
Most reviews about the antibiotic are positive:
- Tatiana . I have had chronic inflammation of the bladder for a long time. I tried many medications, but they were ineffective: the unpleasant symptoms returned after a short time. Azithromycin was recommended by a friend. I took the antibiotic once a day for a week. Six months have already passed, and there have still been no relapses. Therefore, I am satisfied with these tablets.
- Marina . When I notice symptoms of urinary inflammation, I always take Azithromycin. This drug helps me quickly. I consider its cumulative effect to be an additional advantage: it continues to act for another week after taking the last pill. Inexpensive in price, easy to use. Of all the antibiotics I know, Azithromycin is the most effective so far.
- Anna . After pregnancy, cystitis began to bother me often. The doctor advised me to take Azithromycin tablets for a three-day course during exacerbations. All symptoms of inflammation disappeared on the second day. There were no side effects while taking it. This antibiotic is much cheaper than its analogues, but it helps better. Now it is always in the home medicine cabinet.
Indications for use
Azithromycin should be taken for:
- otitis (any form and degree of development);
- sinusitis (especially acute form);
- laryngitis (with prolonged treatment);
- pharyngitis;
- tonsillitis;
- pneumonia (in any form, even with an unknown causative agent);
- bronchitis (any form and degree of development);
- skin diseases caused by infectious infection;
- diseases of the genitourinary system.
Azithromycin for cystitis
Azithromycin is often prescribed for the development of cystitis in women. This disease is associated with inflammation of the bladder (as a result of infection) and is accompanied by severe pain and burning in the lower abdomen. Bloody discharge may occur.
Azithromycin prevents the proliferation of bacteria, stops the inflammatory process and helps restore the functioning of the genitourinary system as a whole. Moreover, the drug is non-toxic, acts “smoothly” and practically does not increase the load on other organs, such as the intestines, liver and kidneys. The antibiotic is cheaper than similar drugs and helps get rid of cystitis even with “protracted” treatment. Activation of the action of Azithromycin (that is, the accumulation in the body of such an amount of the drug that can destroy the infection) occurs three days after starting to take the medicine (one package of three tablets is enough, in the case of a dosage of 500 mg).
Be careful, despite the fact that the drug has virtually no contraindications or side effects, it can only be used with the appropriate prescription from a doctor!
Azithromycin for prostatitis
Azithromycin is well suited for the treatment of prostatitis, an infectious male disease caused by chlamydia. In this case, the antibiotic can be taken both at the initial stage of the disease and during the period of exacerbation. In case of exacerbation, taking the drug for three days is sufficient (1 tablet per day: dosage 500 mg); at the initial stage of the disease, the dosage may be even lower, and the treatment may be shorter. In the most severe and advanced cases, it is prescribed intravenously.
Azithromycin penetrates the blood faster than other antibiotics and blocks the spread of infection. In addition, it has a wider spectrum of action than similar drugs.
However, the drug has a number of contraindications, so it can be used strictly in accordance with the doctor’s prescription.
Pharmacology
In pharmacies, the medicinal drug is found in the form of tablets with a dosage of 500, 250 and 125 mg. There are only three of them in one package, but this is quite enough to defeat cystitis. Finding it is not difficult. It is sold strictly according to a prescription, its price is relatively low - in the region of 60 to 80 rubles.
White tablets have a round shape and a smooth surface. The antibiotic destroys Moraxella, Chlamydia, Neisseria, Legionella, Streptococcus and Staphylococcus. It prevents the spread of inflammatory processes, normalizes the state of biological fluid, prevents relapse, and restores the flora of the urinary organs.
It usually takes no more than 5 days to treat diseases with its help. Based on necessity, the period can be extended to 9 days.
The antibiotic is stored for two years from the date of release. It must be kept in a dry place, out of reach of children, at a temperature not exceeding 25°C.
Side effects
Azithromycin is considered a fairly “safe” antibiotic, but its use can lead to a number of side effects. Among them:
- nausea;
- intestinal upset (rare);
- painful sensations in the abdominal area (if they appear, you must immediately contact a specialist and adjust the course of treatment);
- allergic reactions to the components of the drug;
- skin rash;
- skin itching;
- general weakness;
- headache;
- dizziness;
- vaginitis;
- nephritis.
Interaction with other drugs
Azithromycin should not be taken in combination with other antibiotics, as it is a strong drug. Azithromycin also does not combine well with Warfarin, Digoxin, Disopyramide, Rifabutin and Cyclosporine.
The average cost is 150 rubles.
Such an unpleasant disease as cystitis, an inflammation of the bladder, most often affects representatives of the fairer sex. Of course, not everything is so categorical, and cystitis occurs in both men and children, but women are more predisposed to it. The reason for this is that women’s ureters are wider and shorter than men’s, making it much easier for infections to enter the body. Moreover, this disease can be caused not only by infection, but also by hypothermia, an abundance of spicy food in the diet, and sand coming out of the kidneys. In this case, it is important not to worsen the condition with self-medication, so do not delay your visit to the urologist. An experienced doctor will always be able to choose an effective remedy with minimal side effects.
The appearance of this disease is associated with the following reasons:
- presence of sexual and intestinal infections
- violation of hygiene rules
- hypothermia
- poor nutrition
- stagnation of urine
- surgery, including catheterization
- metabolic disorders
- period of menopause in women.
Symptoms of the disease are usually pronounced:
- pain in the lower abdomen;
- frequent urination, accompanied by burning and stinging;
- in severe cases, fever
- the appearance of blood in the urine.
Whatever the reasons for the disease, it requires timely treatment. Today, there are many drugs available for the effective treatment of cystitis, among which Azithromycin occupies a worthy place.
Azithromycin for cystitis
Azithromycin helped many patients quickly cure cystitis. This is a series of modern antibiotics that effectively destroy pathogenic microorganisms that provoke inflammatory processes.
When choosing a drug, it is necessary to take into account the nature of the disease, the patient’s age, and tendency to allergies. To find out the full picture, you must undergo tests and select a drug based on their results.
Azithromycin is often used to treat cystitis due to its high effectiveness and quite affordable cost. This is an antibiotic of the macrolide group, which differ from other antibiotics in having a more gentle effect on the body. Side effects from this drug are much less than from other similar drugs.
Azithromycin is less toxic than its “brothers”. The action of the drug is based on the destruction of bacterial protein, which blocks their reproduction. As Azithromycin accumulates in the body, its toxicity towards pathogenic flora increases and the bacteria die.
A significant advantage of this remedy is its additional anti-inflammatory effect, which helps eliminate inflammation in the bladder. Since this antibiotic has a slightly different principle of action than its analogues, the process of destroying bacteria does not negatively affect the rest of the body. This drug also has side effects, but there are not many of them.
In order to quickly cure cystitis completely and not encounter this disease again, it is important to adhere to the urologist’s instructions.
General recommendations
It is important to promote the positive effects of the drug on the body in every possible way. Therefore, follow a number of recommendations:
- Follow the diet prescribed by your doctor. If possible, exclude salt and spices from your usual diet, as well as foods containing high amounts of fat. Prefer fruits, vegetables and cereals instead.
- Forget about taking fermented milk products for a while, as they can cause prolonged diarrhea.
- Take the drug with water only. Other drinks such as teas and fruit drinks will negatively affect the healing effect.
- Visit your doctor on time. He must know how the treatment is proceeding.
- Avoid drafts and always dress appropriately for the weather. Also, avoid sitting in cold places.
- Do gymnastic exercises in the mornings and evenings. This will strengthen the immune system and make it much easier to resist bacteria.
Can Azithromycin be trusted?
Cystitis that is not fully treated will periodically remind itself, occurring at the slightest hypothermia or after a prolonged cold. All this contributes to the development of the disease into the chronic stage. It is much harder to get rid of a chronic disease than a primary one. Therefore, in this case it is very thoughtless to limit ourselves only to drugs that relieve pain.
Azithromycin is one of those drugs that can cure even advanced forms of cystitis. Its advantage is that it costs significantly less than drugs with a similar mode of action. Maximum activity of the drug occurs after a few days of administration.
The drug is produced in the form of gelatin capsules containing the antibiotic itself. The dosage can be 250 or 500 mg. The second dosage option is used only for the treatment of adults, for whom the daily dose of this medication for cystitis is 1000 mg. As a rule, to eliminate inflammation, it is enough to take the medicine for 3-5 days.
Who's at risk
The negative effect of Azithromycin on the patient’s body manifests itself in the following diseases:
Reviews of Brusniver for cystitis
- liver failure;
- glomerulonephritis;
- allergies;
- breastfeeding;
- jaundice.
It is unacceptable to self-medicate even with a mild form of cystitis, since the drug is metabolized in the liver and increases the risk of serious complications. Taking an antibiotic and alcohol together can cause severe poisoning or an allergic reaction. How strong its effect on the patient’s body will be depends on the dose of alcohol, the patient’s condition, and the rate of elimination of the drug. It is also necessary to take into account the fact that a person may develop complications from concomitant diseases. In this case, the antibiotic accumulates in the body in high concentration.
The drug is not prescribed for the treatment of children under 6 months of age. If the patient's blood serum has low potassium or magnesium levels, the antibiotic must be taken with caution. Incorrect Azithromycin therapy worsens the condition of patients suffering from severe heart failure, arrhythmia, and diabetes mellitus.
Azithromycin for children and pregnant women
Of course, people have contradictory attitudes towards antibacterial drugs. Some people take medicine without fear, others try to first cure the disease with herbal remedies. However, such remedies are not always effective enough and you still have to resort to antibiotics. And in this case, it is important to choose a drug that will not only help, but also will not bring many side effects.
Let us immediately note that this drug is prohibited for young children; it can be prescribed only from 12 years of age. Teenage girls quite often suffer from cystitis, because they tend to dress lightly even in bad weather, wear synthetic underwear, and do not always maintain hygiene. Such patients can safely be prescribed Azithromycin when the first symptoms of the disease appear! The main thing is not to stop taking the medications as soon as the symptoms disappear, because in this way it is easy to develop chronic cystitis. Typically, adolescents are prescribed the smallest dosage (250 mg).
It is better not to take Azithromycin for pregnant women, but if there is a need for an antibiotic, you can take it starting from the second trimester of pregnancy.
Azithromycin is prohibited for nursing mothers. If it is impossible to avoid taking antibiotics, then you need to temporarily interrupt breastfeeding and resume only after the drug is removed from the body.
Useful tips
For those who decide to fight cystitis with Azithromycin, it will be important to find out some recommendations for taking the drug.
Not compatible with alcohol! Like most antibiotics, Azithromycin in combination with alcohol causes severe intoxication and can even be fatal.
Maintain proper nutrition. During the treatment period, it is very important to supplement the therapy with appropriate nutrition - more vegetable soups, boiled chicken, fresh vegetables, fruits, juices.
If the patient is constantly taking some medicine, it is necessary to find out its compatibility with the chosen antibiotic. This is done, naturally, by a doctor.
Under no circumstances is it recommended to take another antibiotic along with Azithromycin.
It is worth refraining from fermented milk products, as in combination with antibiotics they cause severe diarrhea.
You can take the medicine only with water, not juice or tea.
Are there any contraindications
In the final “summaries” of clinical studies, scientists characterize azithromycin as the safest antibacterial drug with virtually no contraindications. The only exception is individual intolerance to the components of the drug.
The prevailing opinion about caution in the use of medicine in cases of failure of renal and hepatic functions is incorrect. Due to the possibility of rapid metabolic reactions, according to clinical studies, even adjustment of the drug dosage in such cases is not required.
The same applies to pregnant women. Scientists claim that the use of the drug during pregnancy does not cause any damage to the fetus or a toxic effect on it. In any case, the decision to prescribe azithromycin to pregnant women is made by the doctor leading the pregnancy.
Side effects
Like any artificial drug, Azithromycin has its side effects, namely:
Nausea, intestinal upset, dizziness, thrush. Sometimes there are unpleasant sensations in the area of the heart and kidneys.
Allergy. The first symptom of an emerging allergy is itching and rash. If you notice this phenomenon, contact your doctor immediately; you may need to change your medication or adjust the dose.
In general, the drug is well tolerated and quickly relieves cystitis.
Cystitis is often characterized by painful urination and discomfort in the bladder area. The drug Azithromycin for cystitis in women and men helps relieve discomfort and eliminate the inflammatory process. Representatives of the weaker sex are more susceptible to developing the disease. Hypothermia often contributes to the appearance of cystitis. The antibiotic Azithromycin eliminates the inflammatory process and improves the microflora of the urethra.
What properties does the drug have?
The active ingredient of the tablets is an antibiotic of the macrolide group. It affects the most important non-membrane organelle of the bacterial cell, as a result of which the protein joining process is disrupted, followed by arrest of development and elimination of the microorganism.
Depending on the content of the active microelement, the drug can suppress the growth and spread of bacteria, or taking the medication leads to the destruction of pathogenic microorganisms. The medication has an inhibitory effect on streptococci, staphylococci, bordetella, moraxella, gardnerella, neisseria, clostridia, peptostreptococcus. The drug is quite active against pathogens of sexually transmitted infections - chlamydia, mycoplasma, ureaplasma.
After consuming the drug, the main substance is absorbed into the blood and distributed to peripheral tissues. The medication is partially processed in the liver and subsequently excreted in the feces.
Cystitis is one of the diseases of infectious origin. Accompanied by the appearance of an inflammatory process in the wall of the bladder. Pathology occurs when E. coli, as well as streptococci and staphylococci penetrate the mucous membranes.
The drug for cystitis is prescribed for:
- Reducing the growth and development of pathogenic microflora, which has become the source of the disease.
- Reducing pain, improving the functions of the urethra.
- Restoring normal bladder emptying.
As a rule, the medication is taken in multicomponent treatment among several antibacterial agents. The dosage is selected based on the symptoms and severity of inflammation.
How does the medicine work?
Azithromycin is a widely used and effective drug. Therapy performed with this remedy eliminates the inflammatory process in the urethra, acute pain, and normalizes urine test results. But you should not take the medicine for cystitis without a medical prescription - the drug has many contraindications. An antibiotic is often included in complex treatment, and after a therapeutic course, you feel better and get rid of the symptoms of cystitis.
The antibacterial drug Azithromycin belongs to the group of macrolides. Its semi-synthetic components effectively act on a number of gram-positive and gram-negative bacteria. Acute cystitis is an inflammation of an internal organ such as the bladder. Its mucous membrane becomes inflamed under the influence of infection and undergoes some changes. The drug Azithromycin helps with cystitis to eliminate frequent urination and discomfort in the lower abdomen .
Cystitis may also present as severe, burning pain in the bladder area. Discomfortable urination in a woman manifests itself in the form of frequent urge, pain in the abdomen and lower back. You should know that cystitis can lead to the development of various urological complications. Therefore, you should not delay your visit to the urologist. Very often, specialists prescribe Azithromycin to relieve pain in the genitourinary system. Treatment of cystitis with Azithromycin is an effective way to quickly get rid of the infection and inflammatory process.
Azithromycin helps relieve pain when going to the toilet and prevents relapse. It can provide effective help when other medications are ineffective.
In humans, Azithromycin:
- stops the activity of pathogenic bacteria;
- eliminates inflammation;
- normalizes the microflora of the urethra and vagina;
- eliminates pain and painful urination.
If the disease is caused by E. coli, then infectious cystitis is diagnosed. The bacterium enters the body and infects the urinary canal. The effective drug Azithromycin eliminates cystitis, since the components of the drug have a pronounced effect against pathogenic microbes. Once upon a time, cystitis was not considered a disease of a bacterial nature. Antibacterial agents were not included in the therapy, but herbal infusions and hygiene measures were prescribed.
Modern medicine has adopted powerful antibacterial drugs against cystitis. Azithromycin helps to cope with the disease in three days and significantly improve well-being in case of bladder inflammation. Sometimes cystitis can become chronic. In this case, more extensive therapy and long-term treatment of the disease will be required.
Types of antibiotics used
Antibiotics that help against cystitis can belong to different groups.
Actively used:
- Penicillins. Ampicillin has proven itself well, but there is information that in cases of the presence of E. coli as the causative agent of the disease, treatment with ampicillin is ineffective;
- Tetracyclines. A group of drugs often causes unwanted side symptoms, so antibiotics should be taken strictly according to the recommended individual regimen;
- Macrolides. Azithromycin is widely used and is characterized by good tolerability and rapid action. Azithromycin should be taken for a course of 2 to 5 days;
- Monural. This drug can influence not only a wide range of microorganisms, but also provide a pronounced therapeutic effect in just 1 day. The active element included in the composition is called fosfomycin. This substance practically does not cause side symptoms with the exception of rash, heartburn and individual allergies. For severe diseases, the drug should be taken twice according to a special regimen, but Monural is usually taken once.
- Cephalosporins. Antibiotics belonging to this group are ineffective if cystitis is caused by gram-negative pathogens.
Treatment of cystitis in women
Women are more susceptible to developing the disease. Under no circumstances should the genitals and lower abdomen be allowed to become hypothermic. Chronic infectious foci, as well as urogenital infections, contribute to the appearance of frequent urination. Cystitis often accompanies urethritis, gonorrhea, endometritis and other diseases. Often, symptoms of the disease appear after a woman has sat on cold stones.
Prolonged sitting while working at a computer, wearing tight underwear and tights have an extremely negative impact on women's health. Various negative factors contribute to the penetration of infection into the urethra and the onset of the inflammatory process. Cystitis in women always begins acutely and is accompanied by a pulling sensation in the lower abdomen and the urge to go to the toilet.
Treatment of cystitis with Azithromycin should be carried out for about 4-5 days . Take 1 tablet of the drug and monitor the woman’s condition. Douching with herbal decoctions and physiotherapy are also prescribed. Dry heat on the stomach helps cope with cystitis. It is also necessary to control your trips to the toilet, drink a lot of water during treatment to quickly remove the infection from the body.
Overdose
Instructions for use are determined based on the individual characteristics of the person. For adults with acute cystitis, it is advisable to take 0.5 grams per day (drink one tablet) on an empty stomach with water. Adolescents over 12 years of age are prescribed 250 mg per day.
Children have a different reaction to the drug. The amount of the drug is calculated as follows: 10 mg per kilogram of body weight. It is best given to infants in syrup form.
Exceeding the doctor's recommended limit has a serious impact on your health. Unpleasant reactions such as nausea, vomiting, headaches and others occur.
Self-medication is strictly prohibited! Quickly go to the nearest hospital so that the doctor performs gastric lavage and prescribes intestinal sorbents.
Treatment of cystitis in men
Men are also susceptible to cystitis. In representatives of the stronger sex, the disease manifests itself as frequent urination and pain in the lower abdomen. For cystitis in men, Azithromycin helps relieve all discomfort and restore healthy microflora of the urethra. If a man does not treat cystitis, the disease develops further, and the inflammatory process affects the neighboring genital organs and kidneys. The action of the medicine is aimed at eliminating inflammation.
In the modern world, treatment of cystitis is no longer possible without the use of antibiotics. Medicines act directly at the site of inflammation and quickly relieve pain and normalize urination. Azithromycin helps prevent various complications of the disease and carry out treatment without any problems.
Application
Azithromycin should be taken once a day for cystitis . The drug should be used according to the instructions that the manufacturer encloses with each package. The dosage of the drug is prescribed privately. However, the doctor usually prescribes 250-500 mg per day.
The dosage of Azithromycin for cystitis in women may be slightly reduced if side effects occur. In general, the medicine is well tolerated by the body, and adverse reactions from the body are extremely rare.
The maximum bactericidal effect of taking the drug is observed throughout the entire therapeutic course. The drug accumulates in organic tissues and retains its activity for a long time.
special instructions
It is recommended to take the medicine after meals; on an empty stomach the risk of side effects increases. You should not combine the drug with antibacterial agents from other groups. During therapy, it is recommended to use medications to normalize the intestinal microflora.
When Azithromycin is used with indirect anticoagulants, an increase in the effect of the latter is observed. The medicine slows down the excretion of coagulants, methylprednisolone and its analogues. When consumed simultaneously with food, a delayed onset of the therapeutic effect is noted.
In elderly patients, excessively slow absorption and excretion are observed, especially in the presence of a history of liver and kidney pathologies.
Side effects
In some situations, the body may not perform well when taking antibiotics. A very common side effect when taking antibiotics is diarrhea.
It is also possible that:
- dizziness;
- digestive disorders;
- headaches;
- pain in the abdomen;
- allergies;
- neutropenia;
- angioedema;
- epidermal necrolysis.
In treating the disease, along with the use of Azithromycin, it is important to follow all medical prescriptions. You should not visit the toilet infrequently, otherwise the infection enters the bladder tissue and complications develop. Azithromycin is a drug that helps prevent further spread of bacteria.
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