Ceftriaxone for pyelonephritis how many injections

Ceftriaxone for cystitis and pyelonephritis: instructions and features of use

Today, the most common diseases of the genitourinary system are cystitis and pyelonephritis. Especially, the older a person gets, the greater the likelihood of infection.

Unfortunately, women suffer from these diseases much more often than men, and most often they become chronic. This is due to the structure of the female reproductive system.

The female genital organs are located so low that the likelihood of developing urogenital infections is very high.

In men, they occur mainly against the background of existing pathology for the second time. These may be urethritis and prostatitis.

, antibacterial therapy occupies a special place . Most infections develop against the background of harmful bacteria and rods. In order to choose the right drug, you need to know the cause of the disease and its causative agent. Next, an analysis is carried out to identify antibiotic resistance.

Today there are antibiotics that cope with many urogenital infections - these are cephalosporins. Nowadays, the drug Ceftriaxone has proven itself well.

Treatment of pyelonephritis
Dosage
Contraindications

More information about the drug

Ceftriaxone is a third generation antibiotic that is taken to treat a variety of infections. Belongs to the cephalosporin series.

It absolutely fully meets the requirements necessary for the treatment of urological infections. The drug copes well with the treatment of cystitis and pyelonephritis. Effective against infections caused by streptococcus, staphylococcus, Haemophilus influenzae and other bacteria.

Ceftriaxone is a powder that comes in different dosages. The drug can be administered intravenously or intramuscularly. This remedy has almost no contraindications, as it is indicated even for the treatment of elderly people, pregnant women and children. The duration of treatment with ceftriaxone is from 7 to 14 days , it all depends on the severity of the disease.

Compound

Active ingredient: ceftriaxone sodium

Available in the following dosages:

Release form

Crystalline white powder for intravenous or intramuscular injection. The medicine is produced in colorless bottles with a rubber stopper and an aluminum cap.

Indications

Infections of the respiratory tract and ENT organs.
Genitourinary organs (cystitis, prostatitis, pyelonephritis), gynecological infections.
Skin infections.
Infections of the gastrointestinal tract and abdominal cavity.
Bone infections.
Salmonellosis, typhus.
Sepsis.
To prevent complications after surgery.

Contraindications

Pregnancy (first trimester), hypersensitivity to the active substance, liver and kidney failure.

Side effects

The drug is well tolerated. Rarely, in some cases may occur
From the gastrointestinal tract: nausea, diarrhea, jaundice, hepatitis, pseudomembranous colitis.
Allergic skin reactions: rash, itching.
From the blood system - hypoprothrombinemia.
From the genitourinary area - interstitial nephritis.

With frequent use of the drug, large changes in the cellular composition of the blood may occur.

Storage conditions

The drug can be stored at room temperature not exceeding 25 degrees. The prepared solution should be used immediately and not frozen.

Treatment of cystitis

Cystitis is a female disease that affects the bladder and causes its inflammation.

This happens because the female urinary tract is very short and there is a high probability of various bacteria getting there.

It is very important for the female body not to retain urine and empty the bladder on time; this will reduce the likelihood of infections and prevent the occurrence of many diseases.

But if it was not possible to avoid inflammation, you will have to resort to antibacterial therapy. Third generation cephalosporins cope well with various types of infections. Ceftriaxone is a broad-spectrum antibiotic that treats urogenital conditions, but it must be prescribed by your doctor.

Dosage

For adults, administer 2 grams per day intravenously or intramuscularly (preferably divided into 2 doses)
For complicated infections, it is possible to take a loading dose of up to 4 grams once a day.
For children under 12 years of age, use only individually in a correctly calculated dosage.
The course of application depends on the severity of the infection. Usually 5 to 7 days are sufficient for uncomplicated cystitis.
Ceftriaxone is non-toxic, but to preserve intestinal microflora it should be taken with probiotics.

Contraindications for the treatment of cystitis

No contraindications or side effects have been identified based on studies. If you are intolerant to the components of the antibiotic, it is worth replacing it with a drug from a different series.

The drug can be prescribed to pregnant and nursing mothers, but under the supervision of a doctor.

During lactation, it can be taken under strict medical supervision. Mandatory monitoring of the child for the presence of dysbacteriosis and allergies to the drug. If these signs appear, the antibiotic should be discontinued.

Treatment of pyelonephritis

Pyelonephritis is an inflammatory process with kidney damage, predominantly of bactericidal etiology. Recently, the disease has become very common, affecting 1 in 100 adults and most often affecting women. The disease is accompanied by aching pain in the lower back, nausea, profuse sweating and high fever. The disease can be diagnosed by passing the necessary tests.

Unfortunately, pyelonephritis can only be treated with antibiotics. Among them, ceftriaxone has proven itself well.

Contraindications for the treatment of pyelonephritis

There are no contraindications or side effects in using the drug in the treatment of pyelonephritis. If individual components of the antibiotic are not responsive, it is worth replacing the drug.

The drug can be taken by pregnant and nursing mothers under the strict supervision of the attending physician.

In any case, before using the drug, you should consult a doctor to make a correct diagnosis and only then begin treatment with antibiotics.

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Source: https://KardioBit.ru/pochki/preparaty-pochki/tseftriakson-pri-tsistite-i-pielonefrite-instruktsiya-i-osobennosti-primeneniya

Contraindications for use

This drug is quite toxic in some conditions and concomitant diseases, so its use is contraindicated in :

Allergies to Ceftriaxone and other cephalosporins, as well as to penicillins;
Pregnancy up to 12 weeks (first 3 months);
Breastfeeding period;
Kidney failure;
Liver failure;
Ulcerative lesions of the gastrointestinal tract;
History of the development of inflammation of the small and large intestines (colitis and enteritis) as a reaction to taking cephalosporins;
Premature babies.

clinics-list Ceftriaxone for pyelonephritis in women

Specialization:

Antibacterial

Ceftriaxone is an antibacterial drug, a broad-spectrum antibiotic from the group of third-generation cephalosporins, which is actively used in the treatment of pyelonephritis in women. It contains the active ingredient of the same name - ceftriaxone.

Treatment of pyelonephritis with ceftriaxone

After entering the patient’s body, this drug quickly reaches the site of kidney damage, triggers a series of biochemical processes, during which the formation of cell membranes in bacteria is blocked. This leads to metabolic disorders in the causative agents of pyelonephritis and they die from their own toxins.

In addition to pyelonephritis, Ceftriaxone is also prescribed for bronchitis, pneumonia, otitis, sore throat, purulent processes in the lungs, streptoderma, cystitis, prostatitis, gonorrhea, endocarditis, meningitis, peritonitis, vaginitis, syphilis and other diseases caused by pathogenic bacteria sensitive to the drug.

Ceftriaxone is active against a large number of microorganisms : streptococci, staphylococci, enterobacteria, E. coli, Haemophilus influenzae, Klebsiella, Moraxella, Neisseria, Morganella, Salmonella, Proteus, Yersinia, Shigella, Treponema pallidum, Clostridia, Peptococcus, Fusobacteria, Bacteroides and many others.

Contraindications for use

This drug is quite toxic in some conditions and concomitant diseases, so its use is contraindicated in :

Allergies to Ceftriaxone and other cephalosporins, as well as to penicillins;
Pregnancy up to 12 weeks (first 3 months);
Breastfeeding period;
Kidney failure;
Liver failure;
Ulcerative lesions of the gastrointestinal tract;
History of the development of inflammation of the small and large intestines (colitis and enteritis) as a reaction to taking cephalosporins;
Premature babies.

Directions for use and doses

Ceftriaxone is for injection only (intravenous and intramuscular). The solution with the drug must be prepared immediately before use.

To do this, add 2 ampoules of lidocaine 1% to one bottle of powder for an adult woman with pyelonephritis, shake thoroughly until completely dissolved and a homogeneous transparent liquid is obtained.

Next, the drug is drawn into a sterile syringe.

Intramuscularly , 1 g of medication is injected deep into the gluteal muscle (contents of 1 bottle). The next day, it is recommended to give the injection to the opposite buttock. The duration of treatment is on average 7-10 days.
Intravenous administration of the drug in case of inflammation in the kidneys is used quite rarely. To do this, add 10 ml of water for injection to the vial with the substance and inject 1 g of Ceftriaxone slowly (over 4-5 minutes).

The only criterion for discontinuing the drug is normalization of body temperature, reduction of symptoms of pyelonephritis and restoration of the woman’s laboratory parameters, plus 3-4 days after this.

Use during pregnancy and breastfeeding

During the formation of organs in the fetus, in the first 12 weeks of pregnancy, the use of this drug is extremely contraindicated ; it can cause disturbances in the development of the child and the occurrence of serious abnormalities, even death.

In the subsequent weeks of pregnancy, the drug can be used according to the woman’s indications - if the risk of her disease is higher than the possible risk to the child.

During the period of lactation and the mother absolutely needs treatment, breastfeeding must be abandoned for the entire time of use of Ceftriaxone in order to prevent disturbances in the growth and development of the baby.

Side effects

Side effects from the use of Ceftriaxone do not occur often. The most common of them are the following:

Nausea accompanied by vomiting;
Diarrhea (diarrhea);
Drug-induced hepatitis;
Quincke's edema;
Itchy skin rash of various types;
Anaphylactic shock;
Increased activity of liver enzymes in laboratory parameters;
Fungal infection of the body (candidiasis, thrush); inflammatory changes in the veins during drug administration (injection phlebitis);
Convulsions;
Decrease in blood cells;
Dizziness;
Increased body temperature;
Headache;
General weakness;
Abdominal pain;
Feeling of a rush of blood to the face, to the head;
Presence of blood in the urine (hematuria);
Bronchospasms.

The occurrence of any of the symptoms requires immediate discontinuation of the drug , contacting your doctor and symptomatic therapy.

With an overdose of Ceftriaxone over a long period of time, changes in blood composition occur - hemolytic anemia develops and the number of leukocytes, neutrophils and platelets decreases. For treatment, it is recommended to immediately stop using the drug and prescribe symptomatic medications.

Various release forms

Ceftriaxone is available in bottles with powder for the preparation of an injection solution. the active substance is 500 mg and 1 g. The package contains 5 bottles.

Analogs

The most well-known analogues of Ceftriaxone are: Medaxone (bottle with 1 g of substance), Lendacin (bottle, 250 mg, 1 and 2 g), Cefaxone (bottle, 1 g), Rocephin (bottle 1 g, with solvent), Azaran (bottle, 1 g), Cefogram (bottle of 250, 500 mg and 1 g), Ificef (bottle of 250, 500 mg and 1 g).

Read further:

Source: https://eva-health.ru/medicine/tseftriakson-pri-pielonefrite/

Side effects

Treatment of pyelonephritis with Ceftriaxone, like therapy with any other antibacterial agent, can cause side effects:

dizziness, headaches and convulsions;
hematopoietic disorders, decreased levels of leukocytes, platelets and other blood cells;
pain in the abdominal area, nausea, vomiting, as well as impaired activity of liver enzymes;
allergic manifestations;
swelling, redness, tenderness and swelling at the injection site.

If side effects develop during treatment of pyelonephritis, as well as any discomfort during Ceftriaxone therapy, it is recommended to report them to your doctor. If necessary, the doctor can adjust the dosage of the drug or replace it with an analogue drug (for example, cefotaxime intramuscularly or another synonym in tablets).

How many days to inject ceftriaxone for pyelonephritis

Ceftriaxone is a broad-spectrum antibacterial agent that belongs to the group of third-generation cephalosporins. It is used to treat various infections caused by pathogens sensitive to the drug. Ceftriaxone gives very good results for pyelonephritis.

Before starting treatment for an inflammatory process in the kidney tissue (pyelonephritis), you must make sure that there are no contraindications to Ceftriaxone.

Dosage and method of use

The standard dosage of Ceftriaxone for pyelonephritis is as follows: for patients aged 12 years and older, 1 - 2 g of Ceftriaxone is used once a day, with an interval of 24 hours. If necessary, caused by the severity of the disease or insufficient sensitivity of microorganisms, it is possible to increase the dose to 4 g.

A similar dose is used for the treatment of cystitis in the acute period. Before starting therapy, it is necessary to ensure that the diagnosis is correct; for this, a special examination should be completed.

The duration of the course of therapy is from 7 to 10 days. However, the doctor can prescribe an individual treatment regimen for pyelonephritis and adjust the dose at his own discretion, depending on the severity of the infectious-inflammatory process and the patient’s condition.

Ceftriaxone is used through intravenous, intramuscular, and infusion procedures. For the treatment of pyelonephritis, intramuscular administration of the drug is most often used. For intramuscular administration, 1 g of Ceftriaxone must be diluted in 3.6 ml of water for injection, lidocaine or any solvent that does not contain calcium.

Use of a medication during pregnancy

The use of Ceftriaxone for the treatment of pyelonephritis during the first 12 weeks of pregnancy is not recommended. This can cause severe pathologies in the intrauterine development of the fetus. For this purpose, other drugs are used that do not affect the fetus and do not pass through the placental barrier.

The use of antibiotics during the remaining period of pregnancy is permitted if absolutely necessary, in a situation where the risk to the health of the expectant mother outweighs the possible negative consequences in the development of the child.

If it is necessary to use Ceftriaxone for pyelonephritis during lactation, it is recommended to interrupt breastfeeding for the period of the therapeutic course.

Features of use

In the presence of pathologies of renal function in patients requiring treatment for pyelonephritis, a reduction in the dose of Ceftriaxone is not required.

In case of liver dysfunction there is also no need for dosage adjustment.

When renal and hepatic dysfunction are combined, regular monitoring of the level of Ceftriaxone in the patient's blood is necessary. Based on its indicators, the dose of the drug is adjusted.

It is very important for patients to follow the treatment regimen for pyelonephritis prescribed by the attending physician, since changing the dosage and reducing the duration of the therapeutic course can lead to undesirable consequences.

Drug interactions

The combined use of Ceftriaxone with drugs that reduce platelet aggregation and anticoagulants can cause bleeding.

Concomitant therapy with diuretics may increase the nephrotoxicity of the drugs.

Simultaneous use with other antibiotics for the treatment of pyelonephritis can cause negative manifestations of overdose.

Conclusion

What antibiotics are used to treat kidney disease? Ceftriaxone is considered one of the best antibiotics with maximum effectiveness for the treatment of infectious and inflammatory processes localized in the kidneys.

According to clinical trials, as well as reviews from doctors and patients, this drug is well tolerated, has a minimal number of contraindications and gives a quick positive result in the treatment of pyelonephritis.

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Today, the most common diseases of the genitourinary system are cystitis and pyelonephritis. Especially, the older a person gets, the greater the likelihood of infection.

Unfortunately, women suffer from these diseases much more often than men, and most often they become chronic. This is due to the structure of the female reproductive system.

The female genital organs are located so low that the likelihood of developing urogenital infections is very high.

In men, they occur mainly against the background of existing pathology for the second time. These may be urethritis and prostatitis.

, antibacterial therapy occupies a special place . Most infections develop against the background of harmful bacteria and rods. In order to choose the right drug, you need to know the cause of the disease and its causative agent. Next, an analysis is carried out to identify antibiotic resistance.

Today there are antibiotics that cope with many urogenital infections - these are cephalosporins. Nowadays, the drug Ceftriaxone has proven itself well.

Treatment of pyelonephritis
Dosage
Contraindications

pharmachologic effect

Broad-spectrum cephalosporin antibiotic of the third generation. It has a bactericidal effect, inhibiting the synthesis of the cell wall of microorganisms. Resistant to β-lactamases of most gram-positive and gram-negative bacteria.

Active against gram-positive aerobic bacteria: Staphylococcus aureus (including strains producing penicillinase), Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus viridans; gram-negative aerobic bacteria: Acinetobacter calcoaceticus, Enterobacter aerogenes, Enterobacter cloacae, Escherichia coli, Haemophilus influenzae (including penicillinase-producing strains), Haemophilus parainfluenzae, Klebsiella spp. (including Klebsiella pneumoniae), Moraxella catarrhalis (including penicillinase-producing strains), Morganella morganii, Neisseria gonorrhoeae (including penicillinase-producing strains), Neisseria meningitidis, Proteus mirabilis, Proteus vulgaris, Serratia spp. (including Serratia marcescens), Pseudomonas aeruginosa (certain strains); anaerobic bacteria: Bacteroides fragilis, Clostridium spp. (except Clostridium difficile), Peptostreptococcus spp.

Has in vitro activity against most strains of the following microorganisms, although the clinical significance is unknown: Citrobacter diversus, Citrobacter freundii, Providencia spp. (including Providencia rettgeri), Salmonella spp. (including Salmonella typhi), Shigella spp., Streptococcus agalactiae, Bacteroides bivius, Bacteroides melaninogenicus.

Methicillin-resistant staphylococci are also resistant to cephalosporins, incl. to ceftriaxone. Many strains of group D streptococci and enterococci (including Enterococcus faecalis) are also resistant to ceftriaxone.

Ceftriaxone for chronic pyelonephritis

Ceftriaxone for pyelonephritis is the antibiotic of choice if the patient has no contraindications to taking this drug. It is prescribed in the form of intramuscular or intravenous injections, the adult dosage is 2 g per day (divided into 2 doses), the children’s dosage is 20-75 mg/per 1 kg of the child’s weight. Prescribing the drug to pregnant women in the first trimester is strictly prohibited.

The duration of therapy with Ceftriaxone for pyelonephritis is on average 5 days, sometimes it is extended to 10 days if the disease occurs with complications.

Read in this article

Ceftriaxone analogues for acute pyelonephritis

In addition to Ceftriaxone, the following can be used for acute pyelonephritis:

These drugs have the same main active ingredient, they have an identical therapeutic effect.

Release form, composition and packaging

Powder for the preparation of a solution for intravenous and intramuscular administration, white or white with a yellowish tint.

1 fl.
ceftriaxone (as sodium salt)	500 mg
-»-	1 g
-»-	2 g

Bottles of 10 ml (1) - cardboard packs. Bottles of 10 ml (5) - packs of cardboard. Bottles of 10 ml (10) - packs of cardboard. Bottles of 10 ml (50) - packs of cardboard.

Drug interactions

Ceftriaxone and aminoglycosides are synergistic against many gram-negative bacteria.

When used together with NSAIDs and other antiplatelet agents, the likelihood of bleeding increases.

When used simultaneously with loop diuretics and other nephrotoxic drugs, the risk of nephrotoxicity increases.

The drug is incompatible with ethanol.

Pharmaceutical interactions

Pharmaceutically incompatible with solutions containing other antibiotics.

More information about the drug

Ceftriaxone is a third generation antibiotic that is taken to treat a variety of infections. Belongs to the cephalosporin series.

Indications

Bacterial infections caused by susceptible microorganisms:

abdominal infections (peritonitis,
inflammatory diseases of the gastrointestinal tract,
biliary tract,
incl.
cholangitis,
empyema of the gallbladder);
diseases of the upper and lower respiratory tract (incl.
pneumonia,
lung abscess,
pleural empyema);
bone and joint infections;
skin and soft tissue infections;
urinary tract infections (incl.
pyelonephritis);
bacterial meningitis;
endocarditis;
sepsis;
gonorrhea;
syphilis;
chancroid;
Lyme disease (borreliosis);
typhoid fever;
salmonellosis and salmonella carriage;
infected wounds and burns.

Prevention of postoperative infection.

Infectious diseases in persons with weakened immune systems.

Dosage

For adults, administer 2 grams per day intravenously or intramuscularly (preferably divided into 2 doses)
For complicated infections, it is possible to take a loading dose of up to 4 grams once a day.
For children under 12 years of age, use only individually in a correctly calculated dosage.
The course of application depends on the severity of the infection. Usually 5 to 7 days are sufficient for uncomplicated cystitis.
Ceftriaxone is non-toxic, but to preserve intestinal microflora it should be taken with probiotics.

Treatment with folk remedies for polycystic kidney disease

The formation of cavities with fluid that replace the parenchyma of an organ is called polycystic kidney disease. Treatment with folk remedies for this pathology is practiced in parallel with traditional methods. Since the disease has a genetic predisposition, it is impossible to cure it, but it is possible to stop the pathological process. Traditional recipes, as well as individual therapy or an integrated approach, can alleviate symptoms, slow down or even stop the formation of cysts.

How to treat polycystic kidney disease with folk remedies

This genetic pathology is characterized by the growth of cysts in the kidney cavity. They disrupt basic functions, and visually the organ becomes like a bunch of grapes. As a result of tissue proliferation, the kidney increases in size, which causes unpleasant and sometimes painful symptoms.

Every year the pathology occurs more and more often. Medicine offers several methods and medications to treat this disorder.

One of the ways to stop the disease and alleviate the symptoms is to treat polycystic kidney disease with folk remedies. Recipes are used as an alternative to traditional therapy, as well as in combination with medications.

Treatment with traditional methods has many advantages:

availability;
efficiency;
harmlessness.

In addition, therapy can be done at home and does not take much time. The effect of such treatment will not be long in coming; your general condition will immediately improve, nausea will go away, and metabolic processes will be activated. Treatment with alternative medicine is not inferior to drug therapy and just as effectively removes nitrogen metabolism products, toxins and waste products.

By using the recipes of our ancestors, who tirelessly fought against illnesses, it is possible to stop pathological changes, prevent the development of complications and not harm the kidneys and other internal organs. Before starting treatment, you should consult a doctor, since non-standard methods can still cause harm to health, despite all the safety.

Traditional medicine

There are many recipes, the ingredients for which are not at all difficult to find, they are available to everyone. Preparing medications is also not difficult, but it is important to be prepared that sometimes the course of treatment can last for several months or even a year.

Echinacea against polycystic disease

The beneficial properties of echinacea tincture have been known for a long time. Most often, this herbal preparation is used to boost immunity, and in the case of polycystic kidney disease, it has an immunomodulatory effect, helping the body suppress the growth of cystic formations.

There is no need to prepare the tincture; it is sold at any pharmacy. The course of treatment usually lasts from 3 months to six months. You need to take the drug 3 times a day, 10 drops. Unfortunately, Echinacea has contraindications for use due to its aggressive effects and effects on the immune system. It should be avoided if you are pregnant, at risk of an allergic reaction, or if you have an autoimmune disorder.

Treatment with burdock

Herbs occupy one of the main places among traditional medicine methods in the treatment of various lesions of internal organs. Herbal medicine has a positive effect on the body and helps it cope with dangerous diseases.

For polycystic kidney disease, burdock is used, its leaves are crushed, the juice is squeezed out of the resulting pulp and taken orally.

The course of treatment is one month, if necessary repeated after a month's break. To suppress symptoms and stop the growth of cysts, you need to take one teaspoon of burdock leaf juice 3 times a day. They begin to treat the disease with one spoon per day, gradually increasing the dose.

Mullein flowers

Few people are familiar with the unusual name, but this plant is quite popular among people suffering from kidney dysfunction. Due to its property of resolving cysts in the cavity and on the surface of internal organs, the herb is used for various diseases not only of the kidneys.

Flower tincture is prepared using alcohol. To do this, you need to fill a 250 ml container with dried flowers of the plant and fill it with vodka. Infuse the product for 15 days in a cool, dark place, under a closed lid. Take 10 drops of the tincture once a day, diluting with water. The course of treatment is 3–4 weeks.

Walnuts

The delicious fruits of the walnut tree help relieve inflammation, cleanse the bloodstream and strengthen the body's defenses. Ripe nuts are crushed and mixed with bee honey. The product is infused for a month, and then eaten 1 teaspoon on an empty stomach. You can be treated in this way without taking long breaks, since the combination is absolutely harmless.

Aloe leaves against kidney cysts

The older the plant, the stronger its healing effect. Aloe and juice are used in the treatment of diseases of various origins, congenital kidney pathology is no exception.

It is important to let freshly picked leaves stand; to do this, they are placed in the refrigerator for a week.

After the beneficial properties have been revealed, the aloe leaves are crushed and, together with medicinal herbs, infused in alcohol for 2 weeks. Despite the bitter taste and unpleasant odor, the product allows you to effectively cope with the symptoms of polycystic disease and stops its progression.

Medicinal garlic

Everyone has known about its properties for a long time. Garlic is used against colds, viral diseases, strengthens the immune system, and also treats polycystic kidney disease. In order for the components of the product to have the necessary effect, it is added when preparing dishes.

A special infusion can reduce cysts and stop their growth. A kilogram of crushed garlic is poured with boiled but cooled water in the amount of one liter and left to infuse for a month. It is important to shake the product periodically and then strain through cheesecloth. Take 2 tablespoons of garlic juice three times a day before meals. The unpleasant aftertaste is washed down with warm milk.

Dosage

Treatment of pyelonephritis is similar to the treatment and dosage for cystitis, 2 grams per day divided into two doses. It is also possible to use a loading dose, but only under the supervision of a doctor. The drug is not compatible with alcohol consumption.

The duration of treatment depends on the severity and condition of the patient. In uncomplicated cases, 5 days are sufficient.

Pregnant and lactating women can take it in a hospital under the supervision of a doctor.

Taking the drug should be accompanied by probiotics prescribed by a doctor.