Tsifran for cystitis: features, how to take, reviews

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Published: 12/07/2017

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Helps get rid of the unpleasant and painful symptoms of Tsifran for cystitis. But first you need to study the instructions, clarify the dosage and look at reviews of other patients about the effectiveness of this drug.

Doctors often prescribe antibiotics to treat such diseases, and this is quite justified. After all, the same cystitis is most often caused by specific bacteria, which the body is not able to overcome without such help. Further recommendations in the article are given on the basis that before using the medicine, you consult your doctor.

• Properties of Tsifran
• Indications
• For cystitis
• Treatment regimen
• special instructions
• Contraindications and side effects
• Interaction with other drugs
• Reviews

Properties of Tsifran

This drug contains the active substance ciprofloxacin.
This is a broad-spectrum antibiotic belonging to the series of second-generation fluoroquinolones. That is, its effectiveness is improved compared to previous versions of similar products, and side effects are minimized. Cifran differs from other similar substances in that there is almost no resistance to it, that is, microorganisms do not develop resistance over time. This means that you can be treated with it repeatedly, and improvement appears from the first days of taking the drug.

https://www.youtube.com/watch?v=n0jCD1OUAOQ

The only options when this remedy will be ineffective are the presence of viruses, syphilis, anaerobic bacteria and fungal infection of the mucous membranes. In this case, you should choose a different treatment option.

This antibiotic is used to kill many pathogens. It treats a large number of diseases:

• Pneumonia, pleurisy, empyema, sore throat.
• Inflammation of the middle ear and adenoids.
• All types of blepharitis, acute inflammation of the cornea, keratitis, postoperative rehabilitation.

The drug also shows effectiveness in blepharitis

• Infections of the pelvic organs, pyelonephritis, inflammation of the appendages, oophoritis, inflammation of the prostate, epididymitis, acute and chronic cystitis.

Cifran is used to treat diseases received from a partner; it is often used for problems in the peritoneum and mucous membranes. Dentists prescribe it for severe spasms.

The dosage form of the drug may be different. For the treatment of bladder inflammation, tablets and injection solution are used. The main factor in the correct treatment of this type of disease is an integrated approach. Along with antibiotics, a specialized specialist prescribes anti-inflammatory drugs and herbal medicines.

For uncomplicated cases of the disease, Cifran for cystitis is prescribed at a dosage of 250 mg twice a day. If inflammation provokes severe pain or fever, the dose of the drug is increased to 500 g twice a day. The medicine is taken on an empty stomach and should be taken with a sufficient amount of liquid.

Sometimes a doctor prescribes Tsifran OD for cystitis. This drug has virtually no side effects and has a longer therapeutic period. The dosage of the medicine will directly depend on the detailed diagnosis, the severity of the disease, weight, age and individual characteristics of the patient.

It should be noted that taking antibiotics and other medications is not enough to treat cystitis. A patient suffering from bladder inflammation must strictly adhere to diet and drinking regimen. Nutrition should be as healthy as possible. The basis of the diet should be vegetables and fruits. The volume of fluid consumed per day should be more than three liters per day.

The antibiotic Cifran is effective for cystitis in women and men, as evidenced by patient reviews. To prevent microflora disturbances when taking such medications, it is advisable to take probiotic medications. They have a beneficial effect on the human immune system, which contributes to a speedy recovery and restoration of the vital functions of the body.

“Cifran” is the commercial name of a drug whose chemical composition is ciprofloxacin. It was discovered more than 50 years ago and belongs to the second generation of fluoroquinolones.

Many people call ciprofloxacin an antibiotic. Fluoroquinolones are antibacterial compounds, but not antibiotics in the strict sense of the term.

"Cifran" is produced by Indian pharmaceutical companies. This is a much improved formula of an old, proven remedy for cystitis and more.

Types of disease and diagnosis

There are two types of cystitis: acute and chronic.
Acute occurs due to factors that provoke it with pronounced symptoms. The chronic form appears due to other diseases present in the person. Cystitis is also divided into bacterial and non-bacterial. Non-bacterial occurs due to irritation by foreign factors - medicinal or chemical. Bacterial cystitis is caused by respiratory bacteria, intestinal microflora and other microorganisms. In the acute form, pronounced symptoms of cystitis are observed: pain in the lower abdomen, painful and frequent urination - up to several times an hour. In severe cases, body temperature rises. Unlike the acute form, with chronic cystitis, symptoms may be completely absent.

Diagnosing cystitis today is not difficult. A complete examination consists of tests such as bacterial urine culture, general analysis, Nechiporenko urine analysis, as well as ultrasound of the genitourinary organs, and, in rare cases, a biopsy.

Interaction with other drugs

Taking an antibiotic can lead to the following side symptoms:

• painful sensations in the abdominal area;
• pressure drop;
• impaired pain perception;
• nausea;
• anxiety;
• diarrhea;
• rapid heartbeat;
• loss of appetite;
• tinnitus;
• increased fatigue;
• sleep problems;
• arrhythmias;
• hearing impairment;
• change in taste;
• increased sweating;
• hives;
• increased risk of tendon rupture;
• fever of a medicinal nature;
• cholestatic jaundice if there is a predisposition.

The medicine has an effect on driving, so while taking Cifran you should avoid using a car or other complex mechanisms that require increased concentration.

The drug interaction of Tsifran is characterized by the following features:

• increasing theophylline concentration;
• increased stimulation of the nervous system when using non-steroidal and anti-inflammatory drugs.

Observe the following rules:

1. There should be an interval of at least 4 hours between taking an antibiotic and products containing aluminum, sucralfate, magnesium, zinc and iron.
2. It is necessary to monitor the coagulogram with the simultaneous use of Warfarin and Tsifran.

“Tsifran” for cystitis, according to most reviews, gives the most noticeable results than for other pathologies. This is ensured by its pharmacodynamics and pharmacokinetics.

When it enters the body through the gastrointestinal tract, the medicine is absorbed into the blood. The drug reaches its highest concentration after 2 hours. Then it circulates in the bloodstream for 4-6 hours, is filtered in the kidneys and is excreted in the urine almost unchanged. It is this mechanism that ensures a high percentage of bacterial pathogen elimination under the influence of “Cifran” from the bladder.

Acting in this way, the product has a bactericidal effect in the place where the pathogen multiplies. By passing through the urethra, urine with ciprofloxacin prevents ascending infection. It is necessary to maintain the amount of medication in the urine at a constantly high level by taking it in accordance with the dosage recommended by the doctor.

The duration of the course of treatment is also determined by the urologist, since it is necessary not only to eliminate painful symptoms, but to completely get rid of bacteria - the causes of cystitis.

Before prescribing Cifran, the doctor will refer the patient for bacteriological culture. This study determines the presence of microorganisms in the urine that could cause cystitis. Normally, urine is sterile and should not contain them. During the culture of material from a person with cystitis, not only the presence of bacteria is detected, but also their genus and species, and an antibiogram is obtained - the sensitivity spectrum of this particular microbe to antibacterial drugs.

This is a very informative analysis, since its results help to prescribe an individual treatment regimen, while the antibacterial sensitivity spectrum makes it possible to identify the pathogen and establish the source of the disease.

This is a mandatory point that cannot be ignored when treating not only with Tsifran, but with any other medications. Chemicals can interact to benefit the body or reduce each other's beneficial properties, as well as aggravate possible side effects.

Cystitis involves not only antibacterial therapy, but also the use of anti-inflammatory drugs, antispasmodics, and analgesics. In addition, the patient may have concomitant somatic or any other diseases.

Caution must be observed when taking Cifran and the following drugs simultaneously:

• theophylline;
• antiretroviral drugs;
• antacids (except H2 receptor blockers);
• non-steroidal anti-inflammatory drugs;
• hypoglycemic drugs (glibenclamide).

Before starting treatment, the doctor must be informed about all medications that the patient is currently taking for other pathologies. Otherwise, undesirable consequences cannot be avoided.

Be sure to notify the specialist during your consultation that you are taking any other medications, vitamins, or even dietary supplements. Tsifran is incompatible with the following drugs:

1. Certain herbal components in combination with an antibiotic can increase the concentration of theophylline in the blood.
2. Medicines to boost the body's immune defense and most anti-inflammatory pills reduce the effectiveness of treatment, but increase the risk of adverse reactions from the central nervous system.

But this drug interacts well with Metronidazole. Therefore, for some indications, doctors prescribe them simultaneously in complex therapy.

https://www.youtube.com/watch?v=9MQL5IZDNOc

Cifran is a broad-spectrum antibiotic. This can be a significant advantage in the treatment of cystitis, because the symptoms of infection are caused by a large number of pathogens, which in some cases can be quite difficult to diagnose.

The drug is available in the form of tablets, ear or eye drops, or injections. It is clear that not all forms of the drug are suitable for the treatment of cystitis. Therefore, when prescribing a medicine by a specialist, be sure to specify what is preferable: tablets or injections.

The principle of action of the drug is based on the blockade of intracellular metabolism in pathogenic microorganisms. Because of this, they stop actively sharing. The cellular structure of microbes is destroyed, as a result of which the infection is first localized and then goes away.

In this case, the active substances of the drug are largely concentrated in the patient’s genitourinary system, that is, in the focus of the inflammatory process. This increases the effectiveness of therapy. Despite the fact that the drug has a complex effect, it is not very effective in combating the following types of pathogens:

• Anaerobic bacteria;
• Viruses;
• The causative agents of syphilis;
• Fungal spores.

These types of microorganisms are resistant to the medicinal components of Tsifran.

The use of ciprofloxacin for cystitis provides a quick and reliable clinical effect and a high degree of eradication of pathogenic microorganisms from the urinary tract due to the bactericidal effect of the drug.

Cifran is excreted unchanged in the urine, its concentration in the lumen and mucous membrane of the bladder significantly exceeds the content in the blood. This provides rapid action against microbes found in the urine and in the surface layer of the epithelium of the bladder and prevents the upward spread of infection. Ciprofloxacin is carried into the deep layers of the organ through the bloodstream, acting on interstitial and intracellular pathogens.

The rapid elimination of pathogenic microbes with a constant high concentration of the active substance allows you to stop the spread of infection and reduce the manifestations of infectious inflammation within a few hours after taking the first dose of the drug. Most patients notice relief on the second day of treatment: pain, discomfort during urination and the number of urges decrease.

How many days to take Tsiprolet for cystitis?

Cystitis is a common infectious disease of the genitourinary system, which affects mainly women (of all patients with this disease, men make up less than 10%). There are many medications that can cope with this problem, but Tsiprolet for cystitis is considered one of the most reliable methods of treatment.

Provided that the disease is diagnosed at an early stage and treatment was started in a timely manner, this remedy can quickly cope with cystitis without any significant side effects on the body.

Instructions for use

Tsiprolet is a broad-spectrum antibiotic drug that helps with chronic and acute forms of cystitis.

The medicine not only relieves symptoms and relieves inflammatory processes, but also prevents the proliferation of residual bacteria, acting at the cellular level.

To treat cystitis, this medicine is used in the form of tablets and solutions for infusion. Tablets are available in two forms - 250 and 500 milligrams. The solution is available in the form of ampoules of 2 mg/ml.

In addition to the treatment of urinary tract infections (including cystitis), the drug is also indicated for diseases of other organs and systems:

• bones and joints;
• ENT organs;
• respiratory tract;
• leather and fabrics;
• genitals;
• oral cavity.

The drug can also be prescribed for preventive purposes after any previous respiratory tract diseases caused by pathogenic microorganisms.

In urology, Tsiprolet is used not only to treat cystitis, but also to eliminate inflammation of the kidneys and pelvic organs; in some cases, the medicine is prescribed in combination with other drugs for the treatment of gynecological and venereal diseases.

The drug is a potent remedy, and sometimes only three tablets are enough for women to eliminate the symptoms of cystitis (if the disease has not progressed to a severe or chronic stage).

Read our article on how to recognize chronic cystitis.

Contraindications and side effects

Tsiprolet has several absolute and relative contraindications:

• individual intolerance to fluoroquinolones, which the drug belongs to, as well as hypersensitivity to the components of the drug;
• pseudomembranous colitis;
• lack of glucose-6-phosphate dehydrogenases in the body;
• atherosclerosis affecting the vascular system of the brain (in this case, the drug can be prescribed, but only after a thorough examination for possible consequences, and treatment should be under the supervision of the attending physician).

Tsiprolet has a lot of side effects, and when treating cystitis the following undesirable effects may occur:

• pain and burning at the injection site;
• nausea and vomiting;
• development of superinfection;
• pain in the abdominal area;
• diarrhea and flatulence;
• general weakness of the body;
• dizziness and headaches;
• urinary retention;
• fatigue during the day;
• bloody discharge in the urinary fluid (hematuria).

Side effects of an emotional and psychological nature are also possible: insomnia, anxiety; nightmares, hallucinations, depression, confusion.

Dosage for cystitis

If cystitis is diagnosed in an acute, uncomplicated form, tablets are most often prescribed, which must be taken twice a day with an interval of 12 hours between doses (tablets in the form of 250 milligrams are sufficient).

Tablets of 500 milligrams are taken in the same way, but only for severe forms of the disease.

The total daily dose of medication should not exceed 1,000 milligrams.

Also, in advanced and severe forms, infusions can be prescribed, which are administered over half an hour and an hour in amounts of 200 and 400 milligrams, respectively.

Such solutions can be used together with a solution of sodium chloride (0.45%), Ringer's solution, a preparation with a dextrose solution and a ten percent fructose solution.

Interaction with other drugs

Tsiprolet is often prescribed not as a separate drug, but is only part of a comprehensive treatment for cystitis. In this case, it is important to pay attention to what drugs it is used with and how some combinations can affect the body.

Tsiprolet is prohibited from being used with certain drugs, when combined with which the following side effects are possible:

1. When taken with antiarrhythmic drugs, ventricular tachycardia may occur.
2. When taken in parallel with insulin, hypoglycemia develops.
3. Methotrexate when taken with Tsiprolet can give pronounced severe side effects.
4. In combination with Omeprazole, Tsiprolet will have minimal therapeutic effect.
5. When lidocaine is administered, its side effects will be enhanced by the components contained in Tsiprolet.
6. Taking antacids containing calcium, aluminum and magnesium, the absorption of Tsiprolet will decrease.

These are only the basic provisions regarding the inadmissibility of combining Tsiprolet with other drugs, but since each organism is individual, before starting treatment it is necessary to additionally consult with your doctor, since in some cases mutual negative effects can be observed with Tsiprolet and other drugs.

Analogues of the drug

An almost complete analogue of Tsiprolet is Medociprin in tablets, but in addition to it, there are about forty more drugs with similar effects, among which the most common are:

• Ciloxane;
• Tsifran;
• Vero-Ciprofloxacin;
• Ciprofloxabol;
• Tsipromed;
• Ecotsifol;
• Cyprinol;
• Ciprofloxacin hydrochloride.

All these drugs are based on the active substance ciprofloxacin.

Only the attending physician can select analogues, and independent choice of a Tsiprolet substitute may not give the desired effect and even aggravate the course of the disease.

Overdose

Tsifran tablets are available in dosages of 250 mg and 500 mg. Accordingly, a single dose ranges from 250 mg to 750 mg-1000 mg per dose. The drug must be taken 2 times a day. The total daily dose depends on the severity of the condition, etiology of the disease, complications, and localization of the infectious process. Concomitant diseases, patient age, renal filtration capacity, and liver function tests should be taken into account.

The treatment regimen in each case is strictly individual, as is the duration of the course of treatment.

For uncomplicated forms of cystitis, take 1 tablet of 250 mg twice a day. If cystitis is accompanied by severe pain, hematuria, or fever, the dosage is doubled: 1 tablet 500 mg twice a day.

The medicine should be taken before meals with a large volume of liquid. The dosage is calculated only by a specialist based on the following factors:

• Diagnosis;
• Forms and severity of pathology;
• Individual characteristics of health status;
• Weight and age.

Please note that treatment of cystitis with Cifran requires protection from direct sunlight. Otherwise, as a side effect of therapy, a skin reaction to ultraviolet radiation may occur, which will resemble burns. Taking this remedy requires special monitoring of your condition in case of the following associated problems:

• Kidney diseases and liver pathologies;
• Atherosclerosis of blood vessels in the brain;
• Cerebral circulation disorders;
• Epileptic seizures;
• Old age;

We recommend that you familiarize yourself with an antibiotic such as Flemoxin.

Both forms of medication can be used to treat cystitis; tablets are more often prescribed.

The dosage and duration of the course depend on the form and duration of the disease. Since all the antibiotic ends up in the urine, dose adjustment depends little on the patient’s weight.

Pills

Oral administration of Tsifran is effective for all forms of cystitis. Dosages and duration of administration are:

• For uncomplicated acute forms of the disease in women, 500-100 mg per day in two doses for 3-5 days.
• For the prevention of relapses in women and treatment during premenopause, 500 mg once.
• Complicated cystitis - 500 milligrams 2 times a day for a week.

The medicine is taken regardless of meal time, washed down with water. It is better to drink it before eating food - this accelerates absorption and the rate of development of the antibacterial effect.

Administration into a vein is necessary if it is impossible to take oral forms.

The infusion is carried out twice a day, a single dosage is 100 mg for the uncomplicated form, for other cases - 200 mg. The duration of the prescription corresponds to the duration of taking the tablets.

If the drug was used in an increased dose, the side effects will increase. You must visit a hospital to receive medical care.

Depending on the disease itself, the degree of its complexity and neglect, associated problems, the age and weight of the patient, the doctor will select the best dosage of the drug and duration of treatment. It is strictly forbidden to decide on your own how many days to take pills or what quantity suits you best.

The instructions for use refer to the following recommended doses for cystitis:

1. For mild forms of the disease, drink 250 mg twice a day for five days.
2. If the symptoms are acute, the pain is felt particularly strongly, and there is a high temperature, then the dose should be increased to 500 mg in the morning and evening.

Side effects

Like many other antibiotics, Cifran should not be used in the following cases:

1. During pregnancy.
2. For nursing mothers.
3. Children under 18 years old.
4. In the presence of atherosclerosis and problems with cerebral circulation.
5. If you are prone to allergic reactions and individual intolerance to the components of the drug.

Most doctors and patients note that Cifran is easily tolerated. But in some cases, unpleasant reactions of the body are observed:

• disruptions in the digestive system;
• allergic rashes;
• thrush;
• depressive states;
• headache;
• sometimes the perception of the organs of hearing, vision and smell is impaired;
• blood pressure decreases;
• symptoms of arthritis and swelling in the subglobs appear;
• anemia.

Tsifran, like many other medications, has side effects. These include:

• urge to vomit;
• anorexia;
• increased gas formation in the intestines;
• bowel dysfunction (usually diarrhea);
• decreased blood pressure;
• feeling dazed;
• violation of orientation in space;
• exacerbation of arthritis, arthrosis;
• allergic reactions (usually itching and rashes on the skin);
• weakness;
• migraine;
• nervous overexcitability, tearfulness;
• insomnia;
• photophobia;
• convulsions.

If the above symptoms appear, the patient should consult a doctor as soon as possible. Some reactions may require discontinuation of the drug.

Before using the medicine needed for treatment, you should study it in detail, read the instructions, and read the list of possible side effects. "Cifran" is taken orally, therefore, undesirable reactions from the digestive system may occur:

• nausea of ​​varying severity;
• decreased appetite;
• aversion to certain foods;
• flatulence;
• stool disorders.

The appearance of attacks of nausea is noted in their reviews by approximately 18% of patients who were treated for cystitis with this remedy. According to their observations, on the second or third day the discomfort goes away, nausea no longer appears.

Dyspeptic symptoms (decreased appetite, reluctance to eat certain foods) are observed in a small number of patients, up to 10% of the total.

Flatulence and stool upset are characteristic phenomena of an imbalance in the microbial biocenosis in the intestine. They accompany the intake of almost any antibacterial drug passing through the gastrointestinal tract. To reduce such reactions to a minimum, it is necessary to include in complex therapy bacterial preparations based on bifidobacteria and lactobacilli to compensate for the processes of food digestion. Sometimes vaginal candidiasis develops. In men, such side effects from the genital organs practically do not occur.

Individually, the body reacts to taking Cifran with a slight decrease in blood pressure, vestibular disorders: dizziness, a feeling of stupor.

There are descriptions of exacerbation of arthritis or arthrosis during treatment of cystitis. Allergic reactions are characteristic of a significant number of patients; almost every third person noted slight skin itching or rashes when taking the drug.

Neurological side effects include headaches, decreased basal tone, tearfulness, and hyperexcitability. This is a very individual reaction and can occur in approximately 5-10% of the total number of patients.

Contraindications

The drug is prescribed to prevent tissue inflammation after surgery, and for the following infectious diseases:

• Infection of the respiratory system: bronchitis, pharyngitis, sinusitis.
• Bacteria in the ENT cavities: mastoiditis, otitis media, sinusitis.
• Infections of the skin and delicate tissues: burns and scratches with infection, wounds, ulcers, abscesses.
• Diseases of the digestive tract: cholangitis, typhoid fever, peritonitis.
• Inflammation of the pelvic organs, salpingitis, endometritis.
• Bacteria in bone and joint tissues, septic arthritis, osteomyelitis.
• Diseases involving resistant gonococci: pharyngitis, gonorrhea, urethritis, proctitis.
• Infection of the urinary and reproductive system: prostatitis, cystitis, epididymitis, various forms of pyelonephritis.
• Bacteria in an exhausted body, bacteremia, septicemia.

The use of Tsifran is excluded in the following cases:

• Individual intolerance to ciproofloxacin and other components of the drug, previous allergic reactions to other fluorinated quinolones.
• Tizanidine therapy (increases the risk of adverse reactions),
• Pregnancy.

The medicine should not be used while breastfeeding; if it is necessary to use Tsifran, breastfeeding will need to be interrupted during treatment.

In children, the drug is used only for pharmacotherapy of life-threatening severe infectious processes as prescribed by a specialist in the appropriate field, with mandatory consideration of the results of pathogen sensitivity studies.

special instructions

To achieve better results and not harm your body, you need to take this antibiotic strictly according to your doctor’s recommendations:

• At the same time, it is advisable for women to maintain immunity with the help of lactobacilli, echinacea and other means that can keep the vaginal microflora in a healthy state.
• Try to adhere to a gentle diet, which involves avoiding fried, fatty, salty and spicy foods.
• It is strictly forbidden to smoke or drink alcoholic beverages at the same time as the antibiotic.
• The entire period of treatment requires increasing the amount of fluid consumed to two liters per day.
• Avoid exposing your skin to direct sunlight as it may cause burns. For some time after completing the course of therapy, also refrain from walking on sunny streets or in the solarium.

Reviews

Maria, 24 years old, Krasnodar

For chronic cystitis, the doctor prescribed the drug Cifran. Tests showed that there were bacteria in the bladder, so I had to take this antibiotic. The medicine surprised me, because already on day 2 the symptoms of the disease decreased. The course of treatment lasted 5 days, so by the end of taking the medicine she completely recovered.

Elena, 36 years old, Vladimir

Tsifran begins to act quickly. Already in the evening of the first day, the pain decreased and the temperature dropped, which lasted for more than 2 days. A week later, the remaining symptoms also disappeared. There were some negative aspects: there was constant thirst and nausea, and there was bitterness in the mouth. As a result, I was able to get rid of the infection, but I had to endure these inconveniences.

Veronica, 28 years old, Ryazan

The doctor prescribed the medicine Tsifran when going to the hospital. I bought the product at a pharmacy for 380 rubles. I couldn’t take this drug for a long time. Already on the first day, nausea and an unpleasant taste in the mouth appeared. These signs were still tolerable. When her condition worsened so much that she couldn’t even get out of bed, she stopped taking the drug.

Usually, when certain drugs are published, reviews are posted about them. As for Tsifran for cystitis, reviews from patients and doctors about it are of the same nature - an effective and very effective drug for quickly solving this problem. A good drug does not need advertising. Numerous studies and many years of practice are a guarantee of its quality.

But medicines, even of the best quality, cannot serve as a panacea for every patient. All of them have a number of limitations, side effects and indications of compatibility with other drugs taken in parallel. Attempts to take the drug without the knowledge or consultation of a urologist, based only on the reviews of complete strangers, usually end in failure.

Incompatible properties of individual drugs in combination with the use of a potent antibiotic leads to a drug conflict, manifested by anaphylactic shock, loss of consciousness, or intoxication symptoms.

A number of negative reviews are associated with such side effects. Therefore, before taking a medicine, you should familiarize yourself with all its characteristics or follow the exact recommendations of your doctor’s recommendations. In particular, dosages, features of administration and duration of the therapeutic course, especially if the drug is toxic.

Analogues of the drug

Almost every pharmaceutical company represented on the world market produces similar drugs containing the active ingredient ciprofloxacin. These are tablets, solutions, capsules or sachets, which can be selected in the most optimal dose and form of administration. It is absolutely impossible to treat yourself; only a doctor can prescribe adequate therapy.

Cifran can be replaced with drugs from other manufacturers with a similar composition, slow-release ciprofloxacin tablets in an equivalent daily dose, or similar drugs from the fluoroquinolone group.

Ciprofloxacin

Available in the form of tablets of 0.25 or 0.5 grams and a solution for infusion under the trade names Tsiprobay, Tsiprolet, Tsiprinol, Ificipro, or the medicine can be named by its active ingredient.

This form is intended to be taken once a day; one tablet contains the recommended daily dose of the antibiotic, which is 500 and 1000 mg. Their effectiveness is higher than that of the conventional form, but the price is also higher. It is produced under the names Cifran OD and Cipro XR.

Other fluoroquinolones

For pharmacotherapy of urogenital infections, other fluorinated quinolones are prescribed:

• Ofloxacin (Oflox, Zanotsin)
• Levofloxacin (Tavanic, Leflocin, Loxof)
• Norfloxacin (Norbactin).

Compound

The active ingredient contained in the drug Cifran is ciprofloxacin hydrochloride . In tablets, its amount is 500 or 250 milligrams. Excipients used: cellulose, talc, starch, magnesium stearate, colloidal silicon dioxide, starch glycolate, cellulose hydroxypropyl methylate, macrogol 400, titanium dioxide. The tablets are packaged in blisters, 10 pieces per package.

An aqueous solution for infusion is available in 100 ml plastic bottles that contain 200 mg of ciprofloxacin. Additional substances are sodium edetate, lactic acid, sodium chloride, sodium hydroxide and hydrochloric acid.

Method of use

Before starting therapy, consult your doctor, as... only a specialist can choose the right course of treatment. It is not recommended to use an antibiotic yourself, because incorrect use of the medicine increases the likelihood of side effects or pathogens developing resistance to the active substances.

The use of Tsifran depends on the severity of cystitis:

• with a mild form and no complications - every 12 hours, 1 tablet of 250 mg;
• in case of exacerbation of severe forms of inflammation - 500 mg 2 times a day.

The drug is taken on an empty stomach, which leads to increased bioavailability of the drug. During therapy, drink a lot of fluids.

• with a mild form and no complications - every 12 hours, 1 tablet of 250 mg;
• in case of exacerbation of severe forms of inflammation - 500 mg 2 times a day.

Pills

To treat cystitis, doctors can prescribe Cifran in tablet form or as an infusion solution. However, the first option is usually assigned. The official instructions say that the drug can be taken regardless of meals, but it is better to do this half an hour before meals. This way the antibiotic will be better absorbed.

The dosage of the drug for mild forms of the disease will be 500 mg (2 tablets) per day. The dose should be divided into two times, and taken in the morning and evening. The course of treatment is 3-5 days. In case of severe cystitis, the dosage is increased exactly twice - up to 1000 mg per day, divided into two doses. The duration of therapy in this case should be 7 days.

Injecting an antibiotic into a vein is practiced in cases where taking pills is not possible.

Infusion is given to patients 2 times a day. For mild cystitis, the patient is given 100 mg of the drug at a time. As for severe cases, the dosage is increased to 200 mg. The duration of the course of therapy with an infusion solution is similar to the duration of the course of treatment with tablets.

Under no circumstances should you continue therapy with Cifran for more than 14 days.

Cifran is not recommended for pregnant women. This drug has a toxic effect on the fetus, which can lead to disruption of its development. Similar restrictions also apply to breastfeeding patients.

The antibiotic is not prescribed to children and adolescents under 15 years of age. After reaching the specified age, the dosage of the drug will be similar to the dosage for adult patients.

Rationale for use in the treatment of cystitis

Prescriptions of Tsifran for cystitis in women are based on the mechanism of action of the drug, which ensures its antimicrobial activity, and on the excellent pharmacokinetic properties that ensure the effectiveness of treatment.

Antimicrobial activity is achieved by blocking enzymatic secretion in bacterial cells, quickly and reliably, causing its death due to the destruction of the cell wall.

Tsifran for cystitis has a clear advantage over other similar drugs used in the treatment of this pathology, which is due to:

1. Good bioavailability of the drug (from 70 to 85%).
2. Achieving high serum concentrations within an hour. When administered by injection, the time is significantly reduced, which makes it possible to use the drug in threatening conditions (including sepsis).
3. The unique ability to quickly distribute the drug in high concentrations into all tissues and biological fluids of the body (with the exception of the central nervous system). In the structure of the mucous lining of the bladder reservoir, it can even exceed the concentration of the active substance in the plasma, which ensures rapid stabilization of the patient’s condition.
4. High concentrations of the drug on the surface epithelial layer of the MP, which prevents the pathogen from spreading upward.

Indications

Tsifran is prescribed for cystitis and other diseases of bacterial etiology:

1. Pneumonia, pleurisy, empyema, tonsillitis.
2. Otitis and the presence of adenoids.
3. Blepharitis, corneal inflammation, keratitis.
4. As a post-operative recovery.
5. Various diseases of the pelvic organs (pyelonephritis, infection of the appendages, prostatitis, epididymitis, etc.).

Even in complex therapy, many sexually transmitted diseases can be cured with the help of Tsifran.