"Tsiprolet" for cystitis: how to take an antibiotic, reviews of treatment

Composition and release form

The medicine is available in the form of tablets, sold in packs of 10 pieces. in each. The active components are:

• ciprofloxacin (500 mg) is an antimicrobial substance that leads to the death of pathogens;
• tinidazole (600 mg) - has an antimicrobial and antiprotozoal effect, negatively affects bacterial cell membranes.

The drug also contains other components that have auxiliary value:

• talc;
• yellow dye;
• corn starch;
• dimethicone;
• microcrystalline cellulose;
• titanium dioxide;
• croscarmellose sodium;
• polysorbate 80;
• macrogol 6000;
• hypromellose;
• sodium carboxymethyl starch;
• Magnesium stearate.

Directions for use and doses

The medicine is prescribed only by a doctor. Before starting therapy, it is necessary to undergo tests to determine the sensitivity of bacteria to the active substances of the drug. It is forbidden to use the medication yourself, because If Tsiprolet is used incorrectly, pathogens can develop resistance to the drug, so next time the drug will not help.

The drug is taken orally, 1 tablet 2 times a day, 1 hour before meals or 2 hours after meals. The medicine should be taken with a small amount of water. The interval between doses is 12 hours.

"Tsiprolet" for cystitis: how to take an antibiotic, reviews of treatment

Inflammation of the bladder is called cystitis. It can be caused by pathogenic flora or has a non-bacterial etiology. A non-infectious process is detected less frequently and is treated depending on the cause.

In most cases, the inflammatory response is caused by a specific pathogen. Accordingly, urologists prescribe drugs with a certain spectrum of action.

If, during therapy, there is no positive dynamics for some time, a culture is done and another antibiotic is selected.

Choosing the best antibiotic for cystitis

Doctors often recommend a broad-spectrum antimicrobial drug for acute symptoms even before determining the sensitivity of pathogenic microorganisms (if an infectious type of pathology is suspected).

This type of diagnosis shows results in a few weeks. The pronounced symptoms of inflammation do not allow waiting. You need to act immediately.

The antibiotic “Tsiprolet” for cystitis is prescribed precisely in such situations.

Pharmacologists offer a huge selection of antimicrobial drugs. Every year more and more new products come on sale. They are produced artificially, many are semi-synthetic. In infectious cystitis, these substances kill foreign agents and quickly relieve inflammation.

The method of short courses of antibiotic therapy is considered effective. This reduces the cost of treatment and the number of negative consequences. This tactic gives good results when the process is uncomplicated. Doctors take into account the spectrum of action of drugs.

The latest generation of fluoroquinolones have proven themselves better than others. Therefore, urologists are increasingly prescribing treatment for cystitis with Tsiprolet.

When choosing an antibiotic, specialists are guided by the following criteria:

• impact on certain microflora;
• tropism to the urinary system;
• combination with other medications;
• minimal negative reactions;
• ease of reception.

As a rule, cystitis is caused by certain microbes. Not all antibacterial agents act on this range of foreign agents. In addition, these substances do not affect viruses and fungi. For such an infection, specific drugs are prescribed. Antibiotics are needed here as an addition to the main treatment, since a decrease in immunity entails the addition of bacterial flora.

Treatment of cystitis requires medications that target the tissues of the bladder. The active substance of such drugs quickly accumulates in the wall of the organ and is retained by it for a long time. This ensures maximum therapeutic results. In such a case, the medicine does not need to be taken frequently. This is important to consider when treatment occurs on an outpatient basis.

Antibiotics usually need to be combined with other medications. The prescribed drug must be compatible with certain substances, since the inflammatory process requires complex treatment.

The choice of remedy is influenced by its tolerability. Let it be gentle on the body’s native flora, so that there is no need for subsequent long-term treatment for dysbacteriosis. The drug should cause minimal allergenicity and not irritate the stomach and intestines.

"Tsiprolet": the main advantages of the drug

The drug "Ciprolet" is a fluoroquinolone of the latest generation. The name of the active substance is ciprofloxacin hydrochloride. Its range of therapeutic effects is wide. The priority over other antibiotics is as follows:

• influence on different groups of microbes;
• duration of emergence of resistance to it;
• accumulates in the affected area after a few hours;
• penetrates well into the bladder tissue;
• quickly affects the pathogen;
• lasts a long time in the hearth;
• it is convenient to take;
• does not harm the body’s own flora;
• does not irritate the intestinal tract.

It is recommended to immediately treat inflammation of the bladder with an antimicrobial agent that is sensitive to the agents that caused the process. If the infection is only slightly “muffled”, in the future this will lead to chronicity of the disease. Therapy will then be long and complex.

Use for cystitis

The drug is produced in the form of tablets with a dosage of 250 and 500 mg, there are infusions of 100 ml. Eye drops are also used in medical practice, but they are not used often. An aqueous solution for intravenous administration is prescribed for complicated courses.

It is recommended to take “Tsiprolet” for cystitis in tablet form. Only in severe cases is it administered into the bloodstream in a hospital setting. In this case, the drug is prescribed first by infusion and then orally. This way, the maximum therapeutic effect is immediately achieved, then maintenance treatment is necessary.

According to the instructions, acute uncomplicated cystitis requires taking 1 tablet of 500 mg or 2 tablets of 250 mg twice a day for three to five days. If there is no improvement in the condition, the drug is discontinued and another one is prescribed. When symptoms alleviate, the dose is reduced (250 mg every 12 hours) and administration is extended to 7 days. Usually the course lasts no more than 10 days.

If an exacerbation of a chronic process occurs, the treatment regimen will be as follows: 500 mg per day for a total duration of one week.

It is recommended to take the tablets before meals, preferably on an empty stomach. You need to take the drug with plain water.

All substances containing calcium reduce the ability of Tsiprolet to be absorbed, so the amount of dairy products is limited during the period of administration.

Contraindications and side effects

Like every medicinal drug, Tsiprolet causes negative reactions and consequences during use. Contraindications include severe individual sensitivity to the substance. The medicine is also not prescribed to teenagers and children: it can have a bad effect on bone formation. If there are problems with the intestines, the drug may increase their manifestations.

The periods of gestation and breastfeeding are a special time when women are very cautiously recommended to take any medications. Patients with confirmed atherosclerosis require special attention. The doctor also takes into account all possible complications when treating cystitis.

Negative consequences of taking the drug include:

• problems in the functioning of the heart and blood vessels;
• changes in the condition of central and peripheral nerves;
• disruptions of the gastrointestinal tract;
• deterioration in the formation of blood cells;
• allergies;
• increased sensitivity to light.

The drug is well tolerated, negative reactions and consequences are quite rare. The condition may worsen in the form of changes in heart rate and shortness of breath. This sometimes happens after taking a loading dose in patients with a history of vascular and cardiac problems. When the drug is discontinued, all the negativity goes away.

Possibility of use in complex therapy

The inflammatory process of the bladder in women is often accompanied by problems of the ovaries, uterus and uterine appendages. This complex is usually caused by an association of microorganisms.

This means that several drugs with different effects are used for treatment. They combine antibacterial drugs of different spectrums.

"Tsiprolet" for cystitis in women is prescribed with anti-inflammatory substances, painkillers, nitrofuran group drugs and sulfonamides.

Men get cystitis less often. This disease is provoked by the following reasons:

• prostate problems;
• foci of chronic infection;
• infection through sexual contact.

Congestion and inflammation of the prostate contribute to the spread of the process to the bladder. When the first symptoms appear, you should consult a doctor. The doctor makes a diagnosis and prescribes treatment.

Since there may be several reasons, comprehensive therapy is recommended.

They use not only anti-inflammatory drugs, immunomodulatory drugs, but also antimicrobial drugs of different spectrum.

Among the fluoroquinolones used:

• "Tsiprolet";
• "Nolitsin";
• "Tsifran".

Prostatitis requires strict adherence to the duration of treatment and dosages of drugs. Medical consultation and laboratory diagnostics are required. The doctor takes into account the characteristics of the course, sources of infection, and the presence of chronic foci.

“Tsiprolet” is not recommended to be combined with magnesium, zinc, iron, and aluminum. These elements need to be taken into account in medicines and foods. The interval between the use of such incompatible substances is about three hours.

The rate of absorption of the drug is slowed down by antacids. They are taken 4-5 hours before using the described medication. This recommendation can be applied, for example, to Didanosine.

The combination of large doses of ciprofloxacin with non-steroidal anti-inflammatory drugs can provoke seizures. The exception is acetylsalicylic acid.

If it is necessary to take the drug simultaneously with Cyclosporine, the negative effect on the kidneys should be taken into account. When using Theophylline in parallel, its content in the blood is monitored.

The dose is adjusted according to the indicators to avoid complications.

Actions in case of overdose

In order to avoid unwanted reactions, the drug should be prescribed by a doctor. He also controls the duration, effectiveness and dosage of treatment. The drug is well tolerated and rarely causes adverse reactions. Overdoses occur occasionally. Their danger is that the antidote for ciprofloxacin is not known to medicine.

If severe diarrhea and other symptoms of poisoning appear while taking the drug, stop taking the drug immediately. Emergency measures include gastric lavage with special substances, while giving plenty of fluids and monitoring the patient. If the measures do not have the desired effect, hemo- or peritoneal dialysis is performed.

Drug substitutes for the treatment of cystitis

In case of inflammation of the bladder, preference is given to remedies that quickly help. In addition, the minimum number of side effects, ease of administration, and low price are important. Prescribed for cystitis, “Tsiprolet”, according to patient reviews, is such a drug. If therapy was started on time, the drug will overcome the disease easily and without negative reactions.

About 40 drugs with similar effects are registered. The main one is “Medociprin.” The most common are “Tsifran”, “Tsipromed”, “Tsiprinol”, “Ciloxan”, “Ecotsifol”. The active ingredient is ciprofloxacin.

The attending physician should select similar medications. It is not recommended to do this on your own. The wrong choice may not only not give the desired result, but also worsen the situation.

Patients and specialists about the medicine

The opinions of patients suffering from cystitis are almost all positive. It is noted that the therapeutic effect occurs on the second or third day of administration. Symptoms go away quickly and easily. It is convenient to take the drug, the price is pleasantly surprising.

"Tsiprolet", used for prostatitis, according to men's reviews, works without causing side effects. I really like that you can take it once a day. The only thing I don’t like is that you can’t combine it with dairy products and alcoholic drinks.

Doctors note the rapid onset of positive dynamics. It can be prescribed from the first hours of the disease, without waiting for sensitivity tests. It does not affect the body’s own flora and does not require subsequent corrective treatment. Therapy is carried out on an outpatient basis and does not require constant monitoring.

Source: https://UroMir.ru/vospalenie-mochevogo-puzyrya/lekarstva/ciprolet-pri-cistite-otzyvy.html

Side effects

Side effects may occur during therapy:

1. Allergic reactions: itching, angioedema, fever, sensitivity to ultraviolet radiation, urticaria, shortness of breath, erythema nodosum, vasculitis.
2. From the urinary system: urinary retention, glomerulonephritis, the presence of salt or blood crystals in the urine, pain when emptying the bladder.
3. From the nervous system: dizziness, convulsions, increased fatigue, fainting, loss of coordination, anxiety, depression, headache, confusion, hallucinations, insomnia, migraine, weakness.
4. From the digestive system: hepatitis, vomiting, nausea, loss of appetite, jaundice, flatulence, metallic taste, diarrhea, discomfort in the abdominal area.
5. From the senses: impaired hearing and vision, tinnitus, impaired sense of smell and taste.
6. From the cardiovascular system: tachycardia, arrhythmia, decreased or increased blood pressure.
7. Other manifestations: increased likelihood of tendon rupture, flushing of the face, anemia, arthritis, increased intracranial pressure, pain in muscles and joints, as well as changes in the number of platelets, leukocytes and granulocytes in the blood.

You should immediately seek medical help if these signs appear.

The occurrence of side effects may have a negative impact on driving. You should refrain from traveling by car while taking Tsiprolet.

Patients' opinions

All patients who used Tsiprolet for the treatment of cystitis were satisfied, here are some reviews from grateful patients.

Inflammation of the bladder in women today is not uncommon. This process is accompanied by unpleasant sensations; the antibacterial drug Tsiprolet will help eliminate them.

It has a wide spectrum of action and is often used in urological practice. The dosage and duration of administration are selected by the doctor individually for each patient. Self-medication can provoke the development of serious complications.

Contraindications

Absolute contraindications are:

1. Acute porphyria.
2. Pathologies of the central nervous system that are organic in nature.
3. Bone marrow hematopoiesis disorder.
4. Hypersensitivity to the components of the drug and antibiotics from the fluoroquinolone group.
5. Blood diseases, including those present in the patient’s medical history.

Use Tsiprolet with caution in the following situations:

1. For the treatment of elderly people.
2. In the presence of severe kidney and liver diseases.
3. For mental disorders.
4. In the presence of atherosclerosis or circulatory disorders of the cerebral vessels.
5. For the treatment of patients with a history of seizures.

There is no compatibility with alcohol, because alcohol-containing products in combination with an antibiotic lead to severe poisoning.

Adverse reactions

When using this medicine, the daily dose is divided into two doses, and a single dosage should be taken strictly once every 12 hours. If the patient accidentally missed taking the medicine at the right time, then the next dose should be taken strictly according to the schedule drawn up by the attending physician. Trying to take the missed dose of the drug can lead to an overdose and other unpleasant consequences.

Tsiprolet has two main contraindications:

1. The patient is sensitive to the components of the drug, and this causes an allergic reaction.
2. The patient is a child under 18 years of age.

For pregnant and lactating women, this medication is prescribed only in the presence of acute symptoms of the disease, since the drug can cause allergic reactions and negatively affect the fetus or baby.

Tsiprolet is relatively well tolerated, and its use usually does not cause severe side effects. But we must take into account that when treating patients with myocarditis or other diseases of the cardiovascular system with this drug, shortness of breath may occur at a dose of 0.75 g or higher.

If the patient suffers from ailments of the gastrointestinal tract, then the following side effects are possible when treated with this drug:

1. Heartburn.
2. Stomach upset.
3. Nausea.
4. Flatulence.

Some patients reported cases of side effects on the liver. This was expressed in the manifestation of symptoms of jaundice.

From the autonomic system of patients, the following side effects may occur:

1. Insomnia.
2. Migraine-like headaches.
3. Tremor of the limbs.

In this case, it is necessary to take into account the individuality of each organism. Therefore, if during the course of the main treatment signs of diarrhea or constipation appear, the patient is recommended to take Linex or Nystatin. This prevents dysbiosis from developing.

Interaction with other drugs

When using Tsiprolet simultaneously with other medications, the following effects occur:

1. Exposure to indirect anticoagulants increases, which increases the risk of bleeding.
2. Metabolic transformations of tinidazole are accelerated during the use of Phenobarbital.
3. The negative effect on the kidneys increases with the simultaneous use of Tsiprolet and Cyclosporine.
4. The absorption of ciprofloxacin is reduced during the use of Didanosine, iron-containing drugs and antacids with calcium, magnesium and aluminum.
5. The combined use of Tizanidine and Tsiprolet causes a sharp decrease in blood pressure and drowsiness.
6. The use of uricosuric drugs leads to a deterioration in the excretion of ciprofloxacin and an increase in the concentration of the active substance in plasma.
7. Rifampicin, Erythromycin, aminoglycosides and cephalosporins are characterized by increased therapeutic effects when taken together with Tsiprolet.

What is cystitis?

As a broad-spectrum drug, Tsiprolet is often prescribed as the main drug in the treatment of inflammation of the bladder lining. As practice and reviews of those taking these pills show, the symptoms of cystitis begin to subside approximately 2–3 days after starting to take the antibiotic.

It takes approximately 7 days for the effects of cystitis to completely disappear. But you should not stop taking the medicine after eliminating the unpleasant symptoms. If the drug stops entering the body before it is completely cured, the disease may progress to the chronic stage. Which will periodically bother you. Therefore, it is recommended to wait until complete recovery; this will be much better and safer for the patient.

How to take the drug and the daily dose are determined by the doctor. It must be divided into two steps. It should be consumed one hour before meals or two hours after meals, washed down with clean drinking water. You should drink Tsiprolet for 1 to 2 weeks, depending on the severity of the disease and the recommendations of a specialist who will tell you exactly how much Tsiprolet you need to take.

Tsiprolet is a broad-spectrum antibacterial drug intended for the treatment of infectious and inflammatory diseases occurring in chronic or acute forms. During therapy, the tablets are taken whole with a sufficient amount of liquid. Although there was no deterioration in absorption when taking the drug with or after meals, experts still recommend taking the medicine on an empty stomach.

As with any other antibiotic, the effect of Tsiprolet can be reduced when taken simultaneously with calcium-containing foods (milk, cheese, etc.), so you must avoid such foods during treatment.

It is also necessary to take into account that Tsiprolet may not be combined with other drugs, therefore, during consultation with a doctor, you must inform about the use of any medications. In this case, you should maintain a gap of several hours between doses.

Cystitis is an acute or chronic inflammatory process that occurs in the mucous membrane of the bladder. It is predominantly a female disease. This is explained by the structural features of the genitourinary system - a woman’s urinary canal is wider and shorter, so it is easier for infections to enter through the ascending route.

In men, it is more often due to trauma to the urethra, such as a kidney stone, due to sexually transmitted infections and prostate problems such as adenoma or prostatitis. With these diseases, the prostate, “lying” on the urethra, enlarges and blocks it, which causes stagnation of urine in the bladder and, as a result, inflammation. There is also a descending path - from the kidneys. There are two main reasons: pyelo- or glomerulonephritis and renal tuberculosis.

Signs of cystitis:

• Pain, itching or burning above the pubis.
• I constantly want to go to the toilet.
• Cutting pain at the beginning and end of the urination process (more often in men).
• Common signs of infection: fever, headache, chills, etc.

The diagnosis of cystitis is made by a doctor based on the above symptoms, but additional research can be done to distinguish it from similar diseases, and at the same time find the exact cause. You can’t do an ultrasound of the bladder - you won’t be able to endure so much for enough urine to accumulate, but you can and should check your kidneys and prostate this way.

Cystoscopy is also done - a probe with a video camera is inserted into the bladder through the urethra. In addition, a general urine test is done, a smear from the urethra to check for sexually transmitted infections (gonorrhea and syphilis) and bacterial culture (a drop of urine is applied to the nutrient medium; if there are microbes, they will begin to grow on it, forming colonies).

It is carried out in three directions: fighting infection (etiotropic), preventing development (pathogenetic) and relieving unpleasant sensations (symptomatic). One of the most effective drugs for cystitis, which helps to cope with the disease in a few days, is Tsiprolet.