Sumamed for cystitis: instructions for use, price, analogues

Drugs for infectious cystitis in women

Usually, if cystitis is a complication against the background of a general weakening of the body due to an infectious disease, then antibiotics are used, which will kill two birds with one stone: they will eliminate the pathogen and quickly remove unpleasant symptoms. Examples: antibacterial agents - monural, ciprolet, amoxicillin with trichopolum or sumamed (azithromycin). If antibiotic therapy is not enough to achieve an effect, biseptol or nitroxoline are additionally added. Special attention should be paid to azithromycin. This antibiotic is recognized as one of the most effective drugs in the treatment of genitourinary infections, it is inexpensive, and the relief effect is felt quite quickly from the beginning of therapy with the drug.

During pregnancy

It has long been known that during the period of bearing a child, you should use less synthetic drugs. Antibacterial agents are also included in this list. Sumamed to eliminate the inflammatory process is used only when it really needs to be taken to cure the disease. After all, cystitis usually occurs for a reason; it often manifests itself against the background of sexually transmitted diseases or after suffering another severe infection.

Although pregnancy is a contraindication for the use of sumamed, in rare cases it is prescribed in small dosages, as it can harm the unborn child. During lactation it is strictly forbidden to drink azithromycin. Breastfeeding should be temporarily interrupted during antibiotic therapy.

Sumamed is one of the most effective antibacterial drugs with a moderate anti-inflammatory effect for the treatment of cystitis. Helps to quickly eliminate unpleasant symptoms of the disease, and also treats severe and chronic forms of genitourinary infections. Women can drink it only from the age of twelve. The medicine received many positive reviews from patients who took it.

Release forms

The drug is available in various dosages and dosage forms. The doctor may prescribe:

1. Sumamed in capsules at a dosage of 250 mg - 6 pcs in a blister.
2. Tablets 125 mg – package No. 6.
3. Tablets 500 mg – packaging No. 2 and 3.
4. The drug is in powder form for the preparation of a suspension of 200 mg/5 ml of various volumes - 15, 20, 30 and 37.5 ml.

Table 1. Physical characteristics of TM Sumamed drugs.

Tablet forms are packed in cardboard boxes. Powder for preparing the suspension - in a plastic bottle with a measuring mark.

Cystitis

Especially one that you won’t tell everyone about. And it often happens due to a careless attitude towards health.

It got warmer, and it seemed to you that winter was over - away with warm shoes and warm clothes.

It’s no wonder that on the same day you got cold and wet feet, and already before going to bed you felt something was wrong: heaviness, a nagging pain in the lower abdomen, a frequent urge to urinate.

At night, these sensations prevent you from sleeping, and by the morning they can worsen: urination will become sharply painful, and blood will appear in the urine. This is cystitis - inflammation of the bladder.

Comprehensive treatment of cystitis

Of course, if you get cystitis, you can do nothing: there is a chance that its symptoms will subside on their own - the chance, however, is small, and the risk that the disease will go from an acute to a chronic form is large.

However, if you treat yourself or on the advice of friends, you will hardly be able to avoid this. And cystitis that has become chronic, cystitis that stays with you for a long time, can ruin not only your personal life, but also your career.

So, you guessed that you had cystitis, you went to the urologist, and he confirmed your suspicions. What's next?

Next comes comprehensive treatment of cystitis. A competent doctor will prescribe the antibiotics you need in this situation, as well as uroantiseptics - drugs that destroy bacteria in the urine. The course of treatment for cystitis will also include general hygiene measures.

First of all, this is a diet - it is necessary to exclude salty and spicy foods, spices, alcohol and drink at least one and a half liters of liquid per day: cranberry juice, infusions of medicinal herbs.

During this time, be sure to stay warm and dry, since the feeling of cold can increase the pathological urge to urinate.

Warm sitz baths (37-38*) with chamomile and eucalyptus 2 times a day for 10 minutes are very effective in treating cystitis.

Local thermal treatment also has a positive effect - warming up with a regular bottle filled with warm water (about 40°C) and wrapped in cloth.

Herbal preparations play an important role in the treatment of cystitis. Herbal treatment of cystitis - perhaps this will be useful to you.

Antibiotics and medications

Now about antibiotic treatment. You need to start with effective and modern drugs. Taking Tarivid has a good effect.

The so-called cephalosporins are also indicated - Tsifran, Tsiprobay, Synflox, Tsiprinol (urologists, as a rule, have a reserved attitude towards cephalosporins in the Indian version (Tsiprolet). Rulid and sumamed are quite appropriate and effective in treating cystitis.

In our country there is a myth about the healing properties of chloramphenicol. In Western countries, this drug is considered archaic and is rarely used.

By the way, prescribing nystatin simultaneously with antibiotics is also not practiced. As a prevention of the growth of fungal infections, nystatin is ineffective, and even more so as a prevention of dysbacteriosis.

Women prone to candidiasis should use those medications that help them during exacerbations. These can be tampons with sodium tetraborate (borax in glycerin), vaginal suppositories, pimafucin.

To protect your intestines during antibiotic therapy, take drugs that normalize the composition of the intestinal flora - floradophilus, acidophilus, bactisubtil.

At the end of the course of antibiotics, you should start taking so-called uroantiseptics according to the regimen prescribed by your doctor. This could be nitroxoline, or even better - 5-NOK, nevigramon (negram) or palin (pimidel, urotractin).

Brief description of the drug Sumamed

The active ingredient is azithromycin. This is a broad-spectrum antibiotic. Available in the form of tablets, capsules and powder for suspension. Belongs to the group of macrolide-azalides. It is most effective against gram-positive and gram-negative anaerobic bacteria. It is prescribed not only for genitourinary infections, but also for the treatment of Lyme disease, pneumonia, sore throat, and otitis media. Less commonly prescribed for the treatment of moderate acne and chlamydia. Azithromycin is contraindicated in cases of hypersensitivity to macrolides, individual intolerance to the active ingredient and children under six months of age.

The list of possible side effects is quite long. Disturbances may occur in the digestive system, hematopoietic system, central and peripheral nervous systems, hearing and vision, cardiovascular system, reproductive, urinary systems, musculoskeletal and respiratory systems. Severe allergic reactions often occur. People prone to allergies should avoid using this medication or should take it with caution. Sumamed is also taken with caution in patients with impaired liver and kidney function.

Full instructions for using sumamed are available at the link: https://lekhar.ru/lekarstva/protivomikrobnye-preparaty/sumamed-instrukcija-po-primeneniju/

Is azithromycin effective for cystitis and how to use it

Azithromycin for cystitis is usually prescribed in severe forms of the disease in the acute stage. This is one of the most popular antibiotics among doctors and patients.

In what cases is the drug used?

Azithromycin is produced by various manufacturers under the names:

• Sumamed;
• Azithromycin-forte;
• Chemomycin;
• Sumatrolide solution tablets.

Despite the fact that all these drugs have the same active substance, the differences in prices can be significant. This is due to the fact that expensive products are imported from abroad, and cheap analogues are produced in Russia.

It is used for:

• Sore throat;
• Sinusitis;
• Otitis;
• Scarlet fever;
• Pneumonia;
• Roger;
• Impetigo;
• Dermatoses;
• Urethritis;
• Cervicitis;
• Boreliosis;
• Infectious cystitis.

Such a wide range of diseases is associated with their common infectious genesis.

For cystitis, azithromycin is used only if the infectious origin of this disease is proven.

Methods of using azithromycin

A distinctive feature of this drug is its short course of treatment. Take it no more than once a day for 3-5 days. The effect begins to appear on the second day, but the final effect of Azithromycin appears only on the fifth or seventh day of the course.

The dosage is determined in accordance with age, weight, severity of pathological processes, concomitant diseases, and possible risks of complications.

Azithromycin is sold in tablets containing the active substance in doses of 125, 250 or 500 mg. Adults with acute cystitis are usually prescribed a dosage of 0.25 to 1 g once a day. For younger patients, the dose is determined depending on weight - from 5 to 10 mg per kilogram of human weight.

The bactericidal properties of the drug are based on the ability to destroy bacterial proteins. This does not lead to their immediate death, but slows down the rate of reproduction. As a result, the population of pathogens gradually decreases. If the antibiotic is taken correctly, the number of bacteria will decrease to an insignificant amount.

This mechanism of azithromycin’s fight against microorganisms reduces the magnitude of the negative effects on the body. For this reason, the drug is classified as gentle.

The maximum bactericidal effect is observed at the end of the treatment course. The effect of the drug continues for another five days after the end of administration. The high concentration of the drug in tissues remains throughout the entire course and even after it, because it has a low level of binding of blood plasma to proteins.

To all the wonderful properties of this medicine, one more thing should be added - it fights the inflammatory process. By eliminating pathogens, Azithromycin also inhibits the development of inflammation.

Azithromycin is destroyed in liver tissues and excreted from the body through the gastrointestinal tract with bile.

Side effects and contraindications

Despite the fact that the drug is called gentle, it is still a strong antibiotic, which is inevitably accompanied by a whole range of side effects and contraindications.

Since the liver actively participates in the circulation of this antibiotic, people with dysfunction of this organ are usually prohibited from using azithromycin. This prohibition also applies to the situation of impaired kidney function, as well as manifestations of various types of allergic reactions.

All patients suffering from cystitis of infectious origin may experience the following side effects:

1. The reaction of the digestive system most often manifests itself in nausea, vomiting, flatulence, diarrhea, pain in the stomach and intestines. Rarely, but still transient increases in the activity of liver enzymes and cholestatic jaundice appear. In addition, every antibiotic passing through the intestines inevitably provokes dysbiosis with all the ensuing consequences.
2. Allergies do not happen often, but they can manifest themselves in a variety of ways. During the period of clinical observations, it was possible to identify: urticaria, skin rash, angioedema, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis. Typically, attacks of bronchial asthma of allergic origin are not typical for this drug, but the likelihood of this should not be ignored.
3. The central nervous system shows its rejection of Azithromycin by dizziness, headache, drowsiness and weakness.
4. The circulatory system may respond with changes in blood pressure, leukopenia, neutropenia, thrombocytopenia.
5. On the cardiac side, chest pain and arrhythmia were observed.
6. From the genitourinary system, the development of vaginitis, candidiasis, nephritis, and an increase in the level of residual urea nitrogen is possible. Such consequences are associated with a temporary imbalance of microorganisms. Suppression of bacterial activity leads to the activation of fungi, which provokes the development of fungal diseases.

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There are many side effects, but the likelihood of them occurring is low. In addition, as mentioned above, the treatment course does not last long, and in about a week the body will return to normal.

Interaction with other drugs

It is undesirable to use Azithromycin together with the following medications:

• ergot alkaloids - there is a possibility of developing ergotism;
• warfarin - its effect is enhanced;
• digoxin or digitoxin - there is a risk of developing glycoside intoxication;
• disopyramide - possible development of ventricular fibrillation;
• lovastatin - likely to develop rhabdomyolysis;
• rifabutin - increases the risk of developing neutropenia and leukopenia;
• cyclosporine - the side and toxic reactions of this drug increase.

Only the most common cases of reactions when using drugs together are listed here. However, there are still other rules for treating cystitis with Azithromycin:

1. You cannot drink alcohol in any form and under any circumstances. Antibiotics are generally not compatible with alcohol, because both drugs have a strong effect on the body, especially on the liver and kidneys. There is no need to increase side effects and increase the risk of new diseases.
2. Spicy, salty and too fatty foods should be prohibited. With cystitis, the walls of the bladder are inflamed and therefore irritated. Food with a large amount of substances that irritate the mucous membrane will contribute to the development of the disease and complications.
3. If a person suffers from chronic diseases that require constant use of medications, it is necessary to inform your doctor about this.
4. Do not take other antibacterial drugs together with Azithromycin.
5. During treatment you should avoid dairy products. When combined with antibiotics, they can cause diarrhea.

Treatment with antibiotics requires mandatory adherence to regular use. Any break leads to a restoration of the number of pathogenic microorganisms, as well as their adaptation to the effects of the drug. As a result, you risk getting a chronic form of cystitis that is difficult to treat.

Source: https://UroPraktik.ru/cistit/azitromiczin-pri-czistite.html

How does Sumamed fight cystitis in women?

Once inside the body, the drug gradually fights harmful microorganisms. There are many other antibacterial drugs that quickly kill the pathogen that causes genitourinary infections in women, but azithromycin is interesting because it has the effect of accumulating in the body, which means it acts more smoothly. Despite the large list of possible side effects, they rarely occur due to this property (gradual accumulation of the active substance in the human body). The mechanism of action on bacteria is simple - azithromycin destroys the protein structure of bacteria. As the active substance accumulates in the body of women, the therapeutic effect of the drug against pathogens increases. In addition to the antibacterial effect, the drug has pronounced anti-inflammatory properties.

Sumamed is also notable for the fact that it is able to relieve women from advanced forms of cystitis that have become chronic. You should not take this antibiotic without a doctor's prescription, otherwise you can greatly harm your body.

Specifics of pharmacokinetics

The principle of action of the antibiotic Sumamed is that when dissolved in the mucous membranes and plasma, the active substance destroys the protein, which is the basis of the pathogenic microorganism. As a result, inhibition of the process of bacterial synthesis is observed and infectious inflammation in the mucous walls of the bladder gradually decreases.

The therapeutic effect appears 3 days after the first dose of the antimicrobial drug. Sumamed is characterized by the fact that it dissolves and is absorbed well. With parenteral administration, a faster distribution of the active substance throughout the bloodstream is achieved. According to clinical studies, after a single dose of 500 mg of the drug, bioavailability is 37%.

Most of the half-life products are slowly excreted in the intestines and 6% in the urine, which ensures long-term preservation of the therapeutic effect on inflammation of the hollow organ of the excretory system. It was found that the concentration of the active substance in the affected tissues is 25-30% higher than in healthy areas of the bladder.

Description and composition

Sumamed is a broad-spectrum antibacterial agent of the macrolide group (azalide), which has the following effect on cystitis:

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• Antimicrobial.
• Antibacterial.
• Anti-inflammatory.

Significantly different from its analogues in the least toxicity and more gentle effects.

Under the influence of an antibiotic, the protein that contains harmful microbes is destroyed, and, therefore, they stop reproducing. The drug has a cumulative property, that is, the greater its concentration in the body, the more destructive its effect on the bacteria that provoked cystitis.

Sumamed is a medicinal product produced in Croatia, which contains the following components, depending on the form of release:

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• The active ingredient is azithromycin dihydrate.
• Film shell or capsules.
• Additional elements.

Compared to other similar medications, it has a varied release form. This allows the specialist to plan therapy with its help in the most flexible way.

The medicine is released in the following forms:

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1. The capsules are hard gelatin in structure – 250 mg;
2. Tablets with a blue tint, dispersible or film-coated - 125, 250, 500 and 100 mg;
3. Powder-suspension of white or yellowish-white color for oral administration – 100 mg/5 ml;
4. Lyophilisate for infusion in a bottle is a whitish powder-solution.

The effect of the drug begins within a day or three from the moment of its administration through a destructive effect on pathogens.

The medicine is perfectly absorbed into the body and slowly leaves it, mainly through the liver, providing a longer-lasting effect on harmful microorganisms. Accumulating in the body, the drug is excreted in the urine (6%), and the rest passes through the intestines.

Brusniver for cystitis

Is taking Sumamed justified in the treatment of cystitis?

Cystitis is an inflammatory process in the bladder, most often affecting women. The development of the disease is facilitated by many factors, from simple hypothermia to the occurrence of infections. To avoid serious consequences, you must visit a medical facility. Many representatives of the fair sex were able to get rid of the disease with such a medicine as Sumamed. But is it really that effective?

Taking Sumamed is necessary for the treatment of cystitis

Sumamed - a simple way out of a difficult situation

It's no secret that there is a wide selection of antibiotics on the shelves of pharmacies, which can sometimes be difficult to choose. Not everyone knows what to do if they are bothered by cystitis and what medications will help get rid of it.

It should be taken into account that when choosing a drug, the patient’s age and tendency to various allergies are important. When you contact a urologist, he will most likely refer you for tests and also write a referral to a gynecologist. After determining the cause of the disease, you will be prescribed antibiotics.

Sumamed is distinguished by its effectiveness and reasonable cost. The antibiotic belongs to the group of macrolides. Many people are interested in the question of how drugs belonging to this group affect microbes. It is worth saying that all antibiotics from the macrolide group have significant differences from those drugs that instantly destroy harmful microorganisms and have a detrimental effect on the body.

Sumamed is practically non-toxic than its analogues. It has a more gentle effect on the body. Under the influence of the drug, the protein that makes up all harmful microbes is destroyed, thus losing their ability to reproduce. The more the drug accumulates in the body of women, the more toxic it becomes towards harmful microbes. In other words, a certain concentration of the drug in the body has a detrimental effect on the bacteria that cause cystitis.

Sumamed has almost no negative effects on the body

The main advantage of Sumamed is its anti-inflammatory effect. Due to the fact that the antibiotic acts “smartly” and destroys all microbes gradually, the body practically does not react. There are still some side effects, but they occur extremely rarely.

In order to get rid of the disease in a few days, and also to prevent its reoccurrence, you need to listen to all the recommendations of the urologist. Only a doctor can prescribe a course of treatment and determine the dosage. You should not try to choose medications for cystitis on your own; this can be dangerous to your health.

Sumamed - is it really effective?

If cystitis is not cured on time, it can darken the lives of all women, and at the most inopportune moment. The disease can be acute, then gradually become chronic. It is important to understand that if the disease has become chronic, it will be very difficult to get rid of it. That is why trying to numb the pain with painkillers, and then simply forget about the disease, is nothing more than frivolity.

Timely treatment will not allow inflammation in the urinary tract to become chronic.

If we study the reviews of women who took the drug Sumamed, we can conclude that this is a truly effective medicine. The information that the drug can relieve even the chronic form of the disease gives real hope. The main thing is that such antibiotics cost much less than any other drugs.

But, of course, you don’t need to prepare yourself for the fact that Sumamed will instantly relieve you of cystitis. In order to relieve some symptoms of the disease, it will take at least two to three days.

Description of the drug

Surely many people have already wondered what such a “miracle” medicine looks like. In most cases, the drug is available in the form of capsules, inside of which there is white powder. The dosage for oral administration varies - 250-500 mg. For adults, the second option is more suitable; you need to drink no more than 1000 mg per day. In order to completely get rid of the inflammatory process, it will take up to 5-7 days.

How to treat sensitive patients

All people have a rather contradictory attitude towards antibiotics. Many try to avoid taking such drugs, while others, on the contrary, believe that only they can get rid of inflammation in the body.

The dosage of the drug is chosen depending on the age of the patient

At the time of treatment, you need to understand that with inflammation of the bladder mucosa, no folk remedy may simply not help. Antibiotics for women can be a real salvation for cystitis.

It's no secret that girls often suffer from cystitis when they are teenagers. After all, young ladies rarely dress for the weather, and also wear synthetic underwear. The symptoms can be so severe that they are simply unbearable. You can take Sumamed from 12 years of age. For girls at this age, a small dosage is selected.

Pregnancy and antibiotics

There has been debate for many years regarding whether pregnant women can take antibiotics. No specialist will hide the fact that by taking antibiotics to treat cystitis, women harm their baby. If you cannot do without this drug, doctors can still prescribe it, but in a certain dosage.

If a woman is breastfeeding, Sumamed should never be taken. If you really need an antibiotic, you will have to stop feeding your baby for a while.

Sumamed is not recommended for a nursing mother, but if necessary, it can be prescribed with interruption of feeding

Adviсe

Those women who plan to treat cystitis with this drug need to know some recommendations:

1. Avoid alcohol completely. Under no circumstances should you combine antibiotics and alcohol.
2. Watch your diet. Include chicken meat, fruits, and juices in your diet.
3. You can only take one antibiotic at a time.
4. The capsule with the medicine is washed down exclusively with water.

It is impossible not to mention the possible side effects - nausea, dizziness, thrush. Also, in women, the heart may tingle slightly.

Cystitis is a fairly serious disease that cannot be ignored. Try to contact a medical facility on time, and follow all the advice and recommendations of your doctor.

The video will tell you how to distinguish the antibiotic Sumamed from a fake:

urogenital.ru

Active substance

The main active component of all dosage forms is the macrolide antibiotic azithromycin. The drug belongs to general systemic drugs. ATX code J01FA10.

The active component of Sumamed has a bacteriostatic effect, suppressing the synthesis of protein compounds in the bacterial cell.

Azithromycin is active against the following representatives of pathogenic flora:

1. Gram-positive aerobes - staphylococcus, streptococcus.
2. Gram-negative aerobes - Haemophilus influenzae, Legionella, Pasteurella multicida.
3. Anaerobes – clostidia, prevotella, fusobacteria.
4. Other microorganisms are chlamydia and mycoplasma.

Species that have developed resistance to the macrolide are represented by Escherichia coli, Enterococcus, and methicillin-resistant Staphylococcus aureus.

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The maximum concentration of the active component in body tissues is observed 2 hours after administration. Azithromycin in the form of inactive metabolites is excreted through the urinary system, with bile and feces within 3–4 days. A high level of the active substance in the blood is observed within 5–7 days after the last dose of Sumamed.

Reviews

According to reviews from many patients, Sumamed’s tolerability is good. Unpleasant painful symptoms of inflammation pass quickly. Although, to completely suppress the viral infection in the walls of the bladder, it is important to undergo complete treatment.

It is noteworthy that the drug perfectly treats the chronic form of the disease, which many antibiotics cannot do. And it is affordable for anyone. It has proven high effectiveness due to the active penetration of infectious microorganisms through the cellular barrier. If you follow medical recommendations, there will be no side effects from organs and systems after taking Sumamed.

I got wet in the rain and began to feel pain in the lower abdomen and a burning sensation when urinating. After testing, it turned out that I had cystitis. The doctor prescribed vitamins and Sumamed for a course of 7 days. I felt improvement already on the 3rd day of taking it.

Anna, 38 years old, Krasnoyarsk

I took Cystoral for cystitis for 5 days in a row, but I couldn’t get rid of the burning sensation, itching, pain, and pain when urinating. On the doctor’s advice, I bought Sumamed in capsules and gradually the symptoms began to subside. Additionally, I drank cranberry juice. After 1 course of use for 5 days, the condition improved.

Marina, 28 years old, Moscow

I was diagnosed with chronic cystitis, but I was already tired of going to the doctors. Prescribed diuretics and herbs did not help. The new antibiotic Sumamed saved me, eliminated the burning and pain.

Violetta 44 years old, Yeisk

Application and side effects

Sumamed is used for medical purposes not only for the treatment of cystitis, but also for the treatment of:

1. Infections of all parts of the respiratory tract.
2. Skin infections.
3. Diseases of the gastrointestinal tract, in particular the stomach and duodenum.

It is important to know that this broad-spectrum drug is not able to completely cure cystitis. For a complete cure, complex therapy will be required. Only a qualified doctor can prescribe an effective therapeutic course of medications.

The standard dosage for the treatment of genitourinary tract infections is 250 mg per day for 5-7 days. If cystitis is chronic, then the rate is increased to 500 mg daily. Sumamed for cystitis in a child is taken only from the age of twelve. In this case, dosage therapy of the drug is selected by a specialist individually.

The antibiotic is taken immediately one hour or two hours after eating, drinking a sufficient amount of water.

Like other broad-spectrum medications, Sumamed has a list of contraindications for its use:

• Individual or increased intolerance to certain components.
• Children under 6 months of age due to lack of research.
• Kidney or liver failure.

Impact of main components

The antibiotic Sumamed is characterized by a pronounced bacteriostatic effect, which means that when it enters the patient’s body, the active substance has a depressing effect on the active proliferation of bacteria. At the end of the course of antibiotic therapy, the state of bacteriostasis remains, which leads to complete recovery of the patient from cystitis of infectious etiology.

Many gram () and gram (-) bacteria, as well as anaerobic viruses, are sensitive to the drug Sumamed.

"Sumamed" is available in tablets, capsules, and powder. A suspension is prepared from the latter composition. The main antibiotic substance is azithromycin. It has a detrimental effect on the protein of microbes that cause inflammation of the bladder. After such exposure they do not reproduce. During long-term use, active accumulation of macrolide occurs in the body, which contributes to the rapid destruction of the pathogen.

Sumamed is well absorbed, but is slowly eliminated from the human body. This effect provides a long-lasting therapeutic effect.

The medicine can also help with skin infections and housing and communal services diseases. If cystitis is detected, treatment is carried out with several drugs. Any dose of the drug in question will not eliminate inflammation. Contraindications to its use:

• allergy;
• dysfunction of internal organs.

Particular attention is paid to therapy if a pregnant woman complains of symptoms of bladder inflammation.

Negative effects of the main substance on the fetus are allowed. You should not drink it during breastfeeding.

Adverse reactions

All possible adverse reactions are divided into common and rare. Patients presented the following complaints:

• headache;
• loose stools;
• vomit;
• epigastric pain;
• nausea;
• discomfort in the gastrointestinal tract;
• violation of the blood formula;
• manifestations of various types of hypersensitivity;
• sleep disturbance, excessive nervousness;
• vertigo and spatial disorientation;
• impaired hearing and visual acuity;
• fragility of the capillaries of the nasal mucosa;
• sharp feeling of heat in women;
• rashes, urticaria;
• excessive sweating;
• kidney pain, decreased excretory function;
• increased fatigue;
• arthralgia.

Activation of fungal flora and vaginal dysbiosis during antibiotic therapy with macrolides are extremely rarely diagnosed. If unpleasant symptoms appear, you should inform your doctor and adjust the treatment.

An overdose causes increased side effects. Severe nausea, vomiting, and a sharp decrease in hearing appear. There is no specific antidote. Treatment is aimed at relieving unpleasant symptoms. Gastric lavage and administration of enterosorbents are indicated.

Interaction of antibiotic with other drugs

Taking antacids does not suppress the activity and absorption of azithromycin, but a drop in its concentration in the blood is observed. Taking medications should be spaced out over time.

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During treatment with Cetirizine, no changes in the QT interval were detected. When taking Sumamed and Digoxin, an increase in the concentration of the latter in the blood is observed.

In recommended dosages, azithromycin affects the absorption of certain types of statins, anticonvulsants based on carbamazepine, the antimycotic fluconazole, sildenafil, and theophylline. During simultaneous treatment, dose adjustment of Sumamed and other medications is not required.

Sumamed does not affect anticoagulants, methylprednisolone, or the antibiotic Rifabutin.

Recommendations from urologists

While taking Sumamed, the patient should adhere to some tips:

1. To prevent the development of diseases in the area where the gastrointestinal tract is located, it is necessary to drink tablets and capsules with water in a volume of more than 200 ml.
2. To prevent the negative effect of the drug on the effects of other medications taken in combination, it is forbidden to crush the tablets.
3. Sumamed should not be taken during or immediately after meals. Ignoring this recommendation will lead to a constant manifestation of the gag reflex.
4. With complex treatment, a break of a day is observed between medications. If the patient misses taking one of the drugs, you should take its daily dosage. Repeated appointment time is every other day.

A comprehensive fight against several pathologies, including cystitis, requires constant monitoring of the patient. Additionally, sour dishes are excluded from the menu. If necessary, a nutritionist develops an individual menu.

Directions for use and doses

The dosage and duration of antibiotic treatment is determined by the attending physician. Self-use of the medicine is prohibited. The drug begins to act 12 hours after administration.

If cystitis is treated with capsules or tablets, it is recommended to take them once a day 60 minutes before meals or 2-3 hours after meals. Take the medicine with a glass of water (200 ml).

The daily dose of Sumamed is 250 mg, but if cystitis is severe, the dosage can be increased to 0.5 g.

If, to eliminate the symptoms of a disease such as cystitis, the doctor considers intravenous infusion of medication necessary, then the dose is determined depending on the patient’s weight. Injection dose – 500 mg. An intravenous infusion is given for 1-2 days, and then the patient is transferred to Sumamed tablets or capsules.

The suspension is used in the treatment of children under 3 years of age. Sumemed is given to a child with cystitis once a day on an empty stomach. Treatment lasts 3 days. The doctor determines the dose depending on the child’s weight.

Analogs

To relieve symptoms and eliminate the pathogen, if necessary, the drug can be replaced with analogues.

Effective generics:

• Biseptol,
• Vilprafen,
• Ofloxacin,
• Amoxiclav,
• Augmentin.

Replacement is carried out only by a doctor on an individual basis based on the results of bacterial culture from the inflamed area.

special instructions

Sumamed from the group of macrolides rarely causes allergic reactions because it is excreted through the liver.

When using the drug, you must follow some rules:

1. It should be taken with caution if you have gallbladder diseases.
2. In case of liver dysfunction, the use of the drug should be discontinued due to a possible increase in the growth of pathogenic microflora and relapses of the underlying disease in patients suffering from myasthenia gravis.
3. Azithromycin is not able to affect concentration, so it can be used when performing precision work or driving a vehicle.
4. It is not recommended to combine the drug with Warfarin, Heparin, or alcoholic beverages that can enter into chemical reactions with the medication.
5. At the time of treatment, it is worth adjusting the diet, eliminating foods with high acidity from the diet.

Cautions

Sumamed is a safe macrolide, but it is taken with caution with certain drugs (for example, Heparin). Azithromycin is also contraindicated for use simultaneously with Warfarin. Due to the ability to accumulate in the body, azithromycin is taken in the prescribed dose. Failure to comply with this treatment condition may cause the following side effects:

• intoxication;
• nervousness;
• edema.

https://www.youtube.com/watch?v=V4N > An overdose of the drug increases the level of leukocytes with platelets. At the same time, hearing and smell are impaired, and taste sensations are lost. It has been proven that the likelihood of the above side effects occurring is 1%. To eliminate this clinical picture, the help of doctors is required.

To reduce the likelihood of negative reactions, it is recommended to abstain from alcoholic beverages during therapy. Chicken meat is excluded from the patient's menu.

Reception scheme

Effective dosages are prescribed by the doctor based on the severity of the inflammatory process, the patient’s age, and the presence of chronic diseases.

The regimen for taking Sumamed for cystitis in women depends on the dosage of the drug. The manufacturer's instructions suggest the following doses and frequency of taking the drug:

1. Sumamed in capsules of 250 mg - 1 time per day for 6 days. The drug in this dosage form is taken 1 hour before meals or 2 hours after meals. The presence of a food bolus in the stomach interferes with the absorption of azithromycin. The capsules must not be chewed. Take a sufficient amount of liquid.
2. Sumamed tablets 500 mg - the total therapeutic dose is 1500 mg of the active substance. Take 1 tablet 1 time per day. The drug in tablet form can be taken regardless of food.
3. For cystitis associated with STDs, the initial dose is 2 tablets of 500 mg of active substance on the first day. The next day - 1 tablet.
4. In elderly women, there is no need for dose adjustment.
5. If there is a history of kidney pathologies, then you should adhere to standard dosages of the drug.

The duration of treatment is determined by the doctor. This takes into account the patient’s medical history, the form of cystitis - acute or chronic, and the woman’s reaction to the drug.

Sources used:

• https://lekhar.ru/lekarstva/protivomikrobnye-preparaty/sumamed-pri-cistite-u-zhenshhin/
• https://1labhealth.ru/tsistit/lekarstva/sumamed-ot-tsistita-kak-prinimat.html
• https://cistit.online/lechenye/preparaty/antibiotiki/sumamed
• https://lcistit.ru/primenenie-sumameda-pri-tsistite/
• https://prostatu.guru/preparaty/sumamed.html

Specifics of using the antibiotic Sumamed in the treatment of cystitis

Cystitis is always accompanied by characteristic symptoms, which consist of a malfunction of the urinary system. Most often, inflammation of the mucous walls of the bladder is diagnosed in women. The causes of this disease are many factors. In situations where an infectious etiology of the disease is identified, antibacterial therapy is required. The use of Sumamed for cystitis does not cause toxic effects on the body and at the same time effectively fights pathogenic microorganisms.

Characteristics of the drug

Sumamed belongs to antibiotics from the macrolide pharmacological group. This medication is characterized by low toxicity in contrast to other drugs with similar characteristics. Sumamed is able to cure advanced forms of infectious cystitis.

Release form and composition

This drug is produced by pharmacological companies in different forms, which makes it possible to choose the most comfortable method of taking the antibiotic, taking into account the patient’s health characteristics. In pharmacies you can purchase Sumamed in the following forms: tablets, capsules, lyophilisate.

The base substance in the medication is azithromycin. Additional components vary depending on the form of release of the drug:

• tablets with a fat-soluble film contain calcium hydrogen phosphate, corn starch, magnesium stearate;
• in the lyophilisate for parenteral administration - sodium carbonate and benzoate, sucrose, glycine, fruit flavors;
• in gelatin capsules the powder contains cellulose, magnesium stearate, sodium lauryl sulfate.

The following features of the production of the drug can be distinguished:

Dosage form Dosage of the basic component Antibiotic packaging

Due to the increasing incidence of counterfeit drugs, you should request a license for sale in pharmacies before purchasing the Sumamed antibiotic.

Attention! You should know that the original tablet has a round shape, on one side there is an engraved inscription PLIVA, and on the other - the dosage value of the active substance.

The antibiotic Sumamed is characterized by a pronounced bacteriostatic effect, which means that when it enters the patient’s body, the active substance has a depressing effect on the active proliferation of bacteria. At the end of the course of antibiotic therapy, the state of bacteriostasis remains, which leads to complete recovery of the patient from cystitis of infectious etiology.

Many gram (+) and gram (-) bacteria, as well as anaerobic viruses, are sensitive to the drug Sumamed.

Specifics of pharmacokinetics

The principle of action of the antibiotic Sumamed is that when dissolved in the mucous membranes and plasma, the active substance destroys the protein, which is the basis of the pathogenic microorganism. As a result, inhibition of the process of bacterial synthesis is observed and infectious inflammation in the mucous walls of the bladder gradually decreases.

The therapeutic effect appears 3 days after the first dose of the antimicrobial drug. Sumamed is characterized by the fact that it dissolves and is absorbed well. With parenteral administration, a faster distribution of the active substance throughout the bloodstream is achieved. According to clinical studies, after a single dose of 500 mg of the drug, bioavailability is 37%. This relatively low rate is due to the fact that the liver destroys most of the Sumamed drug. The maximum concentration in blood serum is observed 3 hours after administration.

Most of the half-life products are slowly excreted in the intestines and 6% in the urine, which ensures long-term preservation of the therapeutic effect on inflammation of the hollow organ of the excretory system. It was found that the concentration of the active substance in the affected tissues is 25-30% higher than in healthy areas of the bladder.

Contraindications for use

Remember! The bactericidal antibiotic Sumamed cannot be a panacea in the treatment of infectious cystitis, since this disease requires an integrated approach to the fight against pathogenic microorganisms.

For this reason, the drug should be taken only as prescribed by the attending physician after laboratory determination of the strain of bacteria or fungus.

Despite the fact that the antibiotic Sumamed has a gentle effect on the patient’s body, there are a number of contraindications for use:

1. Severe pathologies of the kidneys and liver that prevent the elimination of half-life products from the body. This in turn provokes excessive accumulation of the active substance in the blood, tissues and further intoxication.
2. Individual heightened sensitivity to the constituent components of the antibiotic.
3. The medication is prescribed with caution to patients with cardiac arrhythmias.

A woman's pregnancy acts as a circumstance for the impossibility of taking Sumamed. As a rule, doctors prescribe antibiotics only for severe complications of infectious cystitis. However, many specialists try to avoid the aggressive effects of these drugs on the gestating fetus and prescribe herbal medications.

Important! During lactation, taking Sumamed is strictly prohibited due to the concentration of the active substance in breast milk.

In situations where antibiotic therapy is unavoidable, you should interrupt the child’s feeding and switch to artificial formula.

Possible side effects

In situations where medical recommendations regarding taking the drug Sumamed were not followed, complications may occur.

In medical practice, the following cases of adverse reactions occur:

Organ system Nature of manifestation

The appearance of the first signs of side effects from various organ systems of the patient cannot be ignored. In the absence of adequate intervention, complications of antibiotic therapy lead to worsening of the disease, and in many cases the risk of death increases.

Treatment regimen

The dosage and duration of treatment is selected individually for each patient. Only with constant monitoring of the dynamics of the disease during antibiotic therapy can a complete recovery be achieved in a short time. Only a doctor is competent to prescribe the medication Sumamed, since it is necessary to take into account the stage of progression of infectious cystitis and the presence of concomitant diseases.

After the results of laboratory tests confirm the bacterial etiology of inflammation of the mucous walls of the bladder, the attending physician draws up a comprehensive treatment plan. The standard course of therapy involves taking Sumamed 250 mg per day for 3-5 days. When diagnosing severe stages of cystitis, doctors increase the daily dosage to 500 mg, with a course duration of about 7 days.

The tablets should be taken with plenty of water (about 200 ml) to prevent irritation of the mucous membranes of the stomach. To avoid gagging, the antibiotic Sumamed should be taken 1 hour before meals or 2 hours after. Chewing and crushing tablets is strictly prohibited due to poor dissolution of the drug. To avoid an overdose of the active substance in tissues and blood serum, this drug should not be taken for more than a week. In medical practice, there are entirely positive reviews from patients who have undergone a course of antibiotic therapy for cystitis.

Basic recommendations for taking an antibiotic

To achieve positive dynamics of infectious lesions of the hollow organ of the excretory system, you should adhere to the basic rules for taking the antibiotic Sumamed. First of all, patients must strictly adhere to the prescribed dosage of the drug. In situations where an excessive amount of the active substance has accumulated in the patient’s body due to an independent violation of the prescribed course of therapy, vomiting, diarrhea and other adverse reactions are observed. If such negative effects occur, you should consult your doctor for help.

A number of recommendations for the use of the drug Sumamed have been developed:

1. In situations where one dose of medication is missed, the required dose should be taken immediately, and the next dose should be taken 24 hours later.
2. During antibiotic therapy, you should completely avoid the use of alcoholic beverages, which come into chemical conflict with medications.
3. There must be constant medical monitoring of the dynamics of cystitis.
4. Taking the drug does not affect the speed of psychomotor reactions of the body, and therefore does not interfere with driving.
5. The antibiotic Sumamed is not compatible with Heparin and Warfarin.
6. You should adjust your diet by eliminating foods with high acidity.

Conclusion

Most patients tolerate the antibiotic Sumamed well. Based on medical practice, a decrease in painful symptoms is observed 3 days after the start of the therapeutic course. However, to completely suppress viral microorganisms in the walls of the bladder, treatment must be completed.

Doctors note that the anti-inflammatory drug can cure chronic cystitis, which cannot be achieved with the help of not all antibiotics. The effectiveness of this drug lies in its ability to overcome the cellular barrier of infectious microorganisms. The high effectiveness and low cost of the drug Sumamed make it so popular among doctors and patients. Compliance with medical recommendations protects patients from the development of unwanted side reactions from organ systems.

uroguru.com

Sumamed - is it really effective?

If cystitis is not cured on time, it can darken the lives of all women, and at the most inopportune moment. The disease can be acute, then gradually become chronic. It is important to understand that if the disease has become chronic, it will be very difficult to get rid of it. That is why trying to numb the pain with painkillers, and then simply forget about the disease, is nothing more than frivolity.

If we study the reviews of women who took the drug Sumamed, we can conclude that this is a truly effective medicine. The information that the drug can relieve even the chronic form of the disease gives real hope. The main thing is that such antibiotics cost much less than any other drugs.

But, of course, you don’t need to prepare yourself for the fact that Sumamed will instantly relieve you of cystitis. In order to relieve some symptoms of the disease, it will take at least two to three days.