Suprax for the treatment of cystitis and pyelonephritis

Brief description of the drug

Suprax is an antibacterial agent and belongs to the 3rd generation cephalosporins. The active substance is cefixime. The drug is presented in capsules and powder for making solutions. You can also find Suprax Solutab containing 400 mg of cefixime in pharmacies. The medicine effectively fights acute and chronic forms of cystitis and pyelonephritis. Can be used in the therapy of children and expectant mothers.

Classification

Based on the nature of its appearance, two types of disease are distinguished:

Primary PN occurs as a result of an inflammatory process in one of the organs.

Secondary – develops against the background of an abnormal structure or dysfunction of the urinary tract.

According to the characteristics of the inflammatory process, PN can be acute or chronic. The course of the acute form does not exceed 2 months . After treatment, the child recovers.

Chronic PN lasts more than 6 months with periodic relapses . During the latent course of this form of the disease, changes in normal parameters are detected in tests, but outwardly symptoms do not appear.

Relapse of the chronic form can be caused by the same pathogen. If another is detected, the disease is considered acute.

The classification of the disease and its complications are presented in the diagram:

Suprax against pyelonephritis: principle of action

The medicine is resistant to enzymes that produce pyelonephritis. The drug is considered a broad-spectrum antibiotic, so it effectively eliminates many pathogenic substances. Despite this, it is not highly toxic, so even small children can be treated with it.

Thanks to its unique composition, Suprax copes well with:

• gonococci;
• streptococci;
• protea;
• Escherichia coli and Haemophilus influenzae.

Once in the body, it begins to fight pyelonephritis gradually. Its maximum concentration in the blood is recorded 4 hours after consumption. The bulk of the drug is excreted by the kidneys.

Dosage for pyelonephritis

As a rule, an adult patient with pyelonephritis needs to take Suprax in a dosage that is half that indicated in the instructions. This is due to the fact that diseased kidneys will not be able to fully perform their work, and a large dose of the drug can provoke kidney failure. To minimize the likelihood of such complications, it is not recommended to independently treat pyelonephritis with Suprax.

Treatment of children

A child under 12 years of age is prescribed granules that need to be diluted.

Suprax for children with pyelonephritis is prescribed according to this scheme:

• 2.5-4 ml for babies up to one year;
• 5 ml for children 2-4 years old;
• 10 ml for a child 5-10 years old.

If the sick child is already 11 years old and weighs more than 50 kg, he can take a tablet with a dosage of 400 mg of cefixime. If the child's weight is less than 50 kg, the dosage is calculated according to the principle of 8 mg per kilogram of weight.

Antibiotic suprax - analogues and instructions for use and reviews

Infectious diseases are a pressing problem of our time, faced by doctors of all specialties.
At the same time, one cannot fail to appreciate the broad importance of antibiotics in the fight against such diseases. After all, for a long time people died from various infections, which are now cured in a few days with the help of antibiotics. One of the best medicines that can cure various diseases is the antibiotic Suprax.

It can be used by both adults and children from 6 months.

Third generation cephalosporin antibiotics are active against many groups of microbes.

Suprax in radar is the most effective semi-synthetic drug that destroys infectious agents and bacteria by suppressing them.

Various pathogens that cause diseases of the kidneys, soft tissues, and respiratory tract exhibit sensitivity to the drug. Sometimes it may be prescribed to treat mild forms of gonorrhea.

On the pharmacological market, the medicine is available in the form of a suspension for children, capsules and granules for adults.

Children are best served by taking a suspension that has a pleasant orange or caramel flavor.

SUPRAX should be taken once a day before or after meals, for 7 days, without interrupting the course of treatment. The daily dose should be determined by the attending physician in accordance with the patient's body weight.

Indications for use of Suprax:

• respiratory tract infections;
• diseases of the urinary system (cystitis, pyelonephritis, urethritis);
• infections of the nose, throat, ear;
• pneumonia;
• diseases of bones and soft tissues;
• a number of inflammatory processes in the tonsils (tonsillitis, similar);
• pharyngitis;
• bronchitis;
• sinusitis;
• sinusitis;
• otitis and ear inflammation.

Contraindications:

• Do not use an antibiotic if you have an allergic reaction or are intolerant to its components;
• It is not recommended to use Suprax while breastfeeding: it is better to stop breastfeeding during treatment;
• Children under 6 months should not take the medicine either: there are no relevant clinical studies;
• Suprax should be used with caution in elderly people; it is less often prescribed for chronic kidney disease.

Active substance

The annotation for the drug states that the active ingredient in the antibiotic Suprax is cefixin. It is characterized by high efficiency, a wide spectrum of antibacterial action, and the safety of its use in children starting from 6 months. Cefixin is active against various microorganisms. It is often used:

• with sore throat;
• respiratory tract infections;
• pharyngitis;
• sinusitis;
• acute bronchitis;
• otitis;
• gram-negative infections in children.

Before treatment, you should definitely do a sensitivity test to the antibiotic Suprax. As a rule, the drug is taken orally only 1 time per day. Rules:

1. Children over 12 years old (weighing more than 50 kg) and adults are prescribed Suprax 400 mg, one tablet per day. Treatment should not last more than 10 days.
2. For children, the drug is calculated based on body weight - 8 mg/kg. Also take 4 mg/kg once or twice a day with an interval of 10 hours, for a course of 6 to 10 days.
3. For kidney disease, the dose must be reduced.

Suspension for children

Suprax suspension is prescribed to children from six months to 12 years. It must be diluted from granules. To do this, you first need to shake the bottle, then add 40 ml of boiled water to it. At the same time, pour in only 20 ml of water, shake the bottle, and only then add the remaining liquid.

Next, shake the bottle until a uniform consistency is formed. Photos of the finished medicine can be found on the Internet. Before each use, the bottle with Suprax should be shaken well. The finished mixture can be stored not in the refrigerator (no longer than 10 days).

Dosage for children depends on the weight and age of the child:

Adult capsules

Suprax for adults is usually produced in capsule form. They must be taken one capsule once a day, regardless of food intake. The course of treatment should not exceed 10 days. Often this drug is prescribed for only a week.

An exception would be diseases caused by streptococcus pyogenes. The course of treatment is exactly 10 days. In case of kidney disease, the dose of the drug is reduced by half or a quarter, based on the level of kidney function.

When using the medicine, it is prohibited to drink alcohol.

Is it possible to use Suprax during pregnancy?

It is not recommended to use the third generation antibiotic Suprax during pregnancy. In case of severe infectious disease, a doctor may prescribe a drug, while assessing the possible risks for the child.

Pregnant women are prescribed Suprax only when other antibacterial agents have not had the desired effect.

During the lactation period, if it is necessary to use the medicine, breastfeeding should be stopped for a while.

Side effects

There are several side effects:

• changes in blood composition;
• severe dizziness, headaches;
• vomiting, nausea, dry mouth, appetite disturbances, diarrhea, bloating, dysbacteriosis, etc.;
• allergic reactions;
• from the urinary tract – renal dysfunction.

An overdose of Suprax can manifest itself as an exacerbation of all of the listed side effects. Typically, stomach or intestinal symptoms may be particularly severe. If an overdose occurs in a child, you should urgently call the hospital. While waiting for the doctor, the patient should rinse the stomach well and give activated charcoal according to body weight.

Before using cheap analogues of the antibiotic Supraxa Solutab, you should make sure that the main active ingredient in the drug is cefixime, and its quantity is not less than in the packaging of the original drug. If you need to buy more packages, the total cost can sometimes be even higher than the original. Unfortunately, not a single Russian manufacturer offers analogues of Suprax.

Reviews about the medicine

Katya, 34 years old: Suprax for a child is the fastest and most effective antibiotic. I think its main advantage is that you don’t have to take tasteless tablets, but simply dilute a suspension that tastes like strawberry yogurt. Suprax has already saved my children (ages 5 and 7 years) several times with acute otitis media and bronchitis.

Igor, 29 years old: I have chronic sinusitis. I tried different antibiotics: there were expensive drugs and not so much. I read the description about Suprax and started taking it. What I would like to note is that it helps immediately, improvement occurs in less than a day. With my illness, it is not always possible to go to homeopathy, so such powerful help is simply a salvation.

Irina, 38 years old: My daughter is 5 years old. After another visit to kindergarten, I came home with a high fever. The local doctor diagnosed us with a sore throat and first prescribed antiviral drugs. Over the course of 4 days there was still no improvement. The doctor decided to start taking the antibiotic Suprax. Our temperature subsided the very next day.

Source: https://sovets.net/5789-antibiotik-supraks.html

Interaction with other pharmaceuticals

The drug should not be prescribed to a patient who suffers from an allergy to penicillin. Simultaneous use with a diuretic or penicillin antibiotic will increase the concentration of cefixime and provoke an overdose.

It is not recommended to combine it with drugs that can negatively affect the kidneys . These are Polymyxin, Gentamicin, Furosemide.

Suprax can stimulate the excretion of OCs, so other contraceptives must be used to prevent pregnancy.

According to reviews from doctors and patients, Suprax really shows good results in the treatment of pyelonephritis. However, it should be taken only as prescribed by a doctor.

Sources:

Vidal : https://www.vidal.ru/drugs/suprax__2432 GRLS : https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGu >

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Metronidazole

Metronidazole is a synthetic antibacterial agent. It has not only antimicrobial, but also antiprotozoal, antitrichomoniacal, and antialcohol activity. In the treatment of pyelonephritis, it is a reserve drug and is rarely prescribed.

The mechanism of action in treatment with metronidazole is based on the integration of the active components of the drug into the respiratory chain of bacteria and protozoa, disruption of respiratory processes and death of pathogen cells.

It is important to remember that antibiotics for pyelonephritis should be prescribed exclusively by a doctor, depending on the severity, the presence of contraindications, the severity of symptoms and the type of disease (acute or chronic). A properly selected antibiotic will not only quickly relieve pain in the kidney area, urination problems and symptoms of intoxication, but also, more importantly, eliminate the cause of the disease.

One of the most common urological inflammations is pyelonephritis (kidney damage). Adults and young patients are susceptible to this virus. From our article you will find out whether Suprax can help with pyelonephritis.

Helped me quickly with an exacerbation of pyelonephritis

How I would like to write a review about some hotel on the seashore! Or at least about a new beautiful dress. But, alas, this year I am without resorts, without travel, and even with a severe exacerbation of chronic pyelonephritis.

The illness began abruptly, and I was sent home from work by taxi. On the first day, I drank what was once prescribed to me in similar cases: an infusion of bearberry leaves and furagin. The improvement in my condition was very slight.

The next morning, a therapist came to the house. She prescribed me the antibiotic Suprax, one capsule a day, as well as Canephron and a urological collection.

The expiration date is also indicated on the box.

My mother went to the pharmacy to buy medicine; she had maximum discounts on her discount card. But even with all the discounts, the amount for the medicine was impressive.

The pharmacist said that the drug is very effective, very strong, you need to take strictly one capsule a day.

Taking the capsules was quite convenient for me. I took it after meals. Nowhere in the instructions did I find any indication of when it is best to take this drug.

Signs and symptoms

Signs of the disease can vary greatly depending on the age of the child and the nature of the inflammatory process. If you have any symptoms of pyelonephritis, you should visit your pediatrician for a diagnosis and treatment.

Acute in infants up to one year old

A child in infancy cannot describe his feelings, but pyelonephritis can be suspected by the following external signs:

temperature increase;

paleness of the skin with blueness of the lips and the area around them;

no weight gain;

anxiety during bowel movements;

Clinic for preschool children

In addition to the symptoms that occur in infants, the child may already indicate moderate pain in the abdomen (umbilical area). It can radiate to the perineum, thigh. Urination becomes painful. And the urine has an unpleasant odor.

In schoolchildren and teenagers

Lumbar pain is felt (mainly on one side) and in the lower abdomen. They are of a pulling nature and fall off when warmed up. Urination is not always impaired. It can be painful, rare or, conversely, frequent.

In adolescents, the disease manifests itself as in adults; learn more about its symptoms from the video:

Chronic

It is observed mainly in children who have suffered an acute form of the disease before the age of 1 year . It is characterized by alternating periods of remission and exacerbations. The chronic nature of inflammation is indicated by:

minor lumbar pain;

an occasional feeling of freezing in the lumbar region;

weak or urgent urge to urinate;

pale skin;

Children with chronic PN may experience impaired psychomotor development, fatigue and irritability .

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How is it different from cystitis?

The symptoms of these two diseases differ; comparison is in this table.

Characteristics of the drug

Suprax is a semi-synthetic antibiotic whose active ingredient is cefixime. The drug affects pathogenic bacteria in the body. It is safe for human body cells.

The medicine is sold in blisters, each of which contains 1, 5 or 7 tablets. Each tablet contains 400 mg of cefixime. As excipients, the drug includes dyes, sweeteners, starch and flavors. They are added to provide organoleptic properties (color, taste, smell) that are pleasant to the patient.

Amoxiclav

Amoxiclav is a semi-synthetic combination drug from the penicillin group, consisting of amoxicillin and an inhibitor of beta-lactamase (bacterial cell enzyme) - clavulonate. Available in tablets (250/125, 500/125, 875/125 mg), powder for dilution and parenteral administration (500/100, 1000/200 mg), powder for suspension (treatment in pediatrics).

The mechanism of action of amoxiclav is based on disruption of the synthesis of peptidoglycan, one of the structural components of the bacterial cell wall. This function is performed by amoxicillin. The potassium salt of clavulanic acid indirectly enhances the effect of amoxicillin by destroying some beta-lactamases, which typically cause bacterial resistance to antibiotics.

Reception features

The course of the drug is determined individually for each patient by his attending physician.

Typically you will need to take the medicine for five days. In this case, it is important to strictly follow the rules of administration, as this allows you to create the necessary concentration of the antibiotic in the patient’s body.

You can take the product in two ways:

• drinking plenty of liquid;
• diluted in a glass of warm water, that is, in the form of a suspension.

Both methods will lead to the same result.

Contraindications

For some diseases, Suprax cannot be prescribed.

It was previously mentioned that it is not recommended to take it during pregnancy and lactation, except in special cases. The drug also negatively affects the functioning of the kidneys and urinary system as a whole, therefore its use is strictly contraindicated in acute and chronic renal failure.

The drug has good compatibility with other drugs, which distinguishes it from other antibiotics. However, there are several groups of drugs with which Suprax is not recommended to be combined:

• indirect anticoagulants;
• carbamazepine;
• carbamazepine analogues.

How to treat kidneys

Treatment of childhood pyelonephritis is best carried out in a highly specialized hospital (in the department of nephrology or urology).

Regimen and diet for illness

In acute form of PN, bed rest or gentle rest depending on the patient's condition.

Nutrition should be gentle on the tubular apparatus of the kidneys. During the acute period, you need to limit your intake of protein foods and salt (no more than 2 g per day). Eliminate pickles and spices.

The drinking regime should be 1.5 times higher than normal. Gradually the child is transferred to table No. 7a, later - to 7b and 7 . After the inflammation is relieved, you can move to table No. 5.

Don’t know what antibiotics to take for children with pharyngitis? This will be discussed in detail in a separate article.

Here you can find out whether compresses help with otitis media in a child, and in what cases they can be used.

Is it possible to treat whooping cough in children at home? You will find all the information about the signs, complications and prevention of the disease on our website.

Medicines

Antibiotics for pyelonephritis in children are the basis of treatment. Before culture results are obtained, the antibiotic is selected empirically, based on which pathogen most often provokes the disease. Cephalosporins (Suprax, Cefuroxime) or “protected” penicillins (Amoxiclav, Augmentin) are prescribed for no more than 10 days.

Based on the results of urine culture, a remedy is selected to combat a specific pathogen. If after a course of taking an antibiotic there is no effect of treatment, the drug must be changed.

Part of the complex treatment should be taking medications that disinfect the urinary tract and inhibit the activity of bacteria (uroseptics - Furadonin, Furamag, etc.). They are used in the second stage of treatment. In case of high temperature and fever, antipyretics are prescribed for the first 2-3 days.

Relapse Prevention

It is carried out in a hospital according to the same principle as for acute pyelonephritis. During periods of remission, planned hospitalization for a detailed examination . During periods of remission, to exclude relapses, a course of antibiotics and uroseptics in small doses, a course of herbal medicine (Canephron, kidney tea, etc.) are prescribed.

After discharge, the child should be regularly monitored by a nephrologist or local pediatrician. Once a month you need to take a general urine test . Routine ultrasound of the kidneys is performed every 6 months.

This video explains more about the symptoms, causes and treatment of the disease: