Normax in the treatment of cystitis: application and treatment regimen

The drug "Normax" is often used for the treatment of cystitis, as it helps eliminate inflammatory processes localized in the bladder, as well as get rid of infection. The pharmaceutical product makes it possible to cope with the disease in the shortest possible time, but despite this it has a number of contraindications for use, so before starting treatment it is important to consult a doctor about the advisability of using this particular medicine.

Composition and beneficial properties of the medicine for cystitis

Normax tablets contain the active ingredient - norfloxacin.
Additional substances are ethanoic acid, sodium chloride, benzalkonium chloride and purified water. The active substance, which is part of the described medication, actively fights gram-negative and gram-positive bacteria. However, with the help of Normax it is not possible to resist infectious diseases that are provoked by anaerobic microorganisms. The drug affects the cellular synthesis of bacterial proteins, subsequently causing their death. The medicine has anti-infective, antimicrobial and bactericidal properties.

Analogs of medication for cystitis

An analogue of the drug is Norilet.
Taking into account the fact that Normax has a number of contraindications for use, it is not suitable for every patient. In such situations, doctors prescribe medications that help fight cystitis and have a similar mechanism of action on the body. The following medications are mainly used:

• "Renor";
• "Norilet";
• "Nolitsin";
• "Chibroxin";
• "Youtibid";
• "Norfloxacin".

Area of ​​application of the drug Normax

whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Normax in the presence of existing structural analogues. Use for the treatment of otitis, cystitis and adnexitis in adults, children, as well as during pregnancy and lactation.

Normax is an antibacterial drug from the fluoroquinolone group. Has a wide spectrum of bactericidal action.

Highly active against gram-negative bacteria: Escherichia coli (Escherichia coli), Haemophilus influenzae, Haemophilus ducreyi, Klebsiella spp. (including Klebsiella pneumoniae (Klebsiella)), Morganella morganii, Neisseria spp. (including Neisseria gonorrhoeae), Salmonella spp. (salmonella), Shigella spp.

Active against gram-positive bacteria: Staphylococcus aureus (including strains producing penicillinase and methicillin-resistant strains), Staphylococcus epidermidis (staphylococcus), Staphylococcus saprophyticus, some strains of Streptococcus spp.

Enterococcus spp. are slightly sensitive to the drug. (enterococcus) and Acinetobacter spp.

Anaerobic bacteria are resistant to Normax.

Norfloxacin excipients.

Pharmacokinetics

When taken orally, 30-40% of the dose is absorbed; food intake reduces the rate of absorption. Norfloxacin is well distributed in the tissues of the genitourinary system. About 30% of the active substance is excreted unchanged in the urine.

When the drug is applied topically, the therapeutic concentration of the active substance is achieved in the tissues and biological fluids of the eye or in the tissues of the ear.

Treatment of infectious and inflammatory diseases caused by microorganisms sensitive to the drug:

• urinary tract diseases;
• infections of the pelvic organs (including adnexitis, prostatitis);
• intestinal infections;
• skin and soft tissue infections;
• infections of the paranasal sinuses, pharynx, larynx, middle ear;
• ophthalmic infections.

• conjunctivitis (including gonococcal);
• keratitis;
• keratoconjunctivitis;
• corneal ulcer;
• blepharitis;
• blepharoconjunctivitis;
• trachoma;
• otitis externa;
• acute and chronic otitis media;
• internal otitis;
• infectious eustachitis.

Prevention of eye infections after removal of a foreign body from the cornea or conjunctiva, after damage by chemical or physical means, before and after surgery.

Prevention of infectious otitis before and after surgery, in case of ear injuries, removal of a foreign body from the external auditory canal, accompanied by damage to ear tissue.

Release forms

Film-coated tablets 400 mg.

Instructions for use and method of use

Prescribe 1-2 drops into the affected eye or ear 4 times a day. If necessary, on the first day of use, the dose can be increased to 1-2 drops every 2 hours. After the symptoms of the disease disappear, use of the drug should be continued for the next 48 hours.

For acute and chronic trachoma, 2 drops are prescribed in each eye 2-4 times a day for 1-2 months.

Before instilling Normax drops into the ear, the external auditory canal should be sanitized. The drops must be at body temperature. The patient should lie on his side or tilt his head back to facilitate instillation. After instillation, you need to let the drops flow into the ear canal, pulling the earlobe down and back. The head should be kept in this position for about 2 minutes. You can place a cotton wool pad in the external auditory canal.

Take 400 mg orally 2 times a day. For severe infections, the single dose can be increased to 800 mg. The duration of treatment is determined individually. The minimum course of treatment is 3 days.

Side effect

• nausea;
• heartburn;
• anorexia;
• diarrhea;
• stomach ache;
• headache;
• dizziness;
• feeling tired;
• sleep disorders;
• irritability;
• sense of anxiety;
• interstitial nephritis;
• skin rash;
• itching;
• Quincke's edema.

Contraindications

• childhood and adolescence up to 15 years;
• pregnancy;
• lactation (breastfeeding);
• hypersensitivity to norfloxacin and other fluoroquinolone drugs.

Use during pregnancy and breastfeeding

The drug Normax is not recommended for use during pregnancy and lactation (breastfeeding).

Use in children

The drug is contraindicated in children and adolescents under 15 years of age.

special instructions

Normax in the form of tablets should be used with caution in patients with epilepsy, convulsive syndrome of other etiologies, severe impairment of liver and/or kidney function.

The drug should be taken at least 2 hours before or 2 hours after taking antacids or drugs containing iron, magnesium, zinc or sucralfate.

Normax in the form of drops is intended for topical use only.

To achieve the best therapeutic effect, drops should be used in combination with systemic antimicrobial therapy (except for mild cases).

The solution and dropper should be protected from contamination.

https://www.youtube.com/watch?v=Gpfwal8-NVs

Impact on the ability to drive vehicles and operate machinery

For 30 minutes after instilling the drug into the eyes, you should refrain from engaging in potentially hazardous activities that require increased attention.

Drug interactions

When taking Normax and warfarin simultaneously, the anticoagulant effect of the latter is enhanced.

When Normax and cyclosporine are taken simultaneously, an increase in the concentration of the latter in the blood plasma is observed.

When Normax is taken simultaneously with antacids or drugs containing iron, magnesium, calcium, zinc, sucralfate, the absorption of norfloxacin is reduced due to the formation of complexons with metal ions.

Norfloxacin solution is incompatible with drugs with a pH value of 3-4 that are physically or chemically unstable.

Analogues of the drug Normax

Structural analogues of the active substance:

• Loxon 400;
• Nolitsin;
• Norbactin;
• Norilet;
• Noroxin;
• Norfacin;
• Norfloxacin;
• Renor;
• Sophazine;
• Chibroxin;
• YouTubeid.

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The drug Normax is an antibacterial agent from the group of fluoroquinolones and is used for inflammatory diseases of internal organs.

The drug Normax is available in the form of enteric-coated tablets intended for oral use. The tablets are packaged in aluminum foil strips of 6 or 10 pieces in a cardboard box with a detailed description attached.

Each tablet of the drug contains 400 mg of the active ingredient - Norfloxacin, as well as a number of additional substances.

Normax tablets are a broad-spectrum antibacterial drug. The drug exhibits high therapeutic activity against the following pathogenic microorganisms:

• Escherichia coli;
• Hemophilus influenza;
• Klebsiella;
• Enterobacteriaceae;
• Shigella;
• Salmonella;
• Gonococci;
• Streptococci;
• Staphylococcus;
• Chlamydia.

Normax tablets are prescribed to patients only after a preliminary examination and assessment of the sensitivity of the pathogen to Norfloxacin. The main indications for use of the drug are the following conditions:

• Inflammatory and infectious diseases of the urinary system - urethritis, pyelitis, pyelonephritis, cystitis;
• Sexual infections – chlamydia, gonorrhea;
• Intestinal infections;
• Diseases of the pelvic organs in men and women - inflammatory pathologies of the uterus and its appendages, inflammation of the prostate gland in men;
• Infectious diseases of soft tissues and subcutaneous fat caused by microorganisms sensitive to Norfloxacin;
• Chronic infectious diseases of the nasopharyngeal area and middle ear caused by microorganisms sensitive to Norfloxacin.

Before starting to use the tablets, the patient is advised to carefully read the accompanying instructions. The tablets have a number of serious contraindications:

• Age up to 15 years due to lack of clinical experience and unknown safety;
• Pregnancy and lactation period;
• Increased individual sensitivity to Norfloxacin or the auxiliary components included in the tablet;
• Severe liver or kidney damage caused by organ dysfunction.

Normax tablets are taken orally, without chewing or crushing, with plenty of water.

Adults and adolescents over 14 years of age are prescribed 1 tablet of the drug 2 times a day. In some cases, the dose of the medicine can be selected by the doctor individually depending on the indications, characteristics of the patient’s body, and the presence of complications.

The duration of treatment with the drug is on average 5-7 days, however, as prescribed by a doctor and if there are indications, the duration of therapy can be extended to 14 days. You should not cancel treatment with the drug yourself, even if the clinical manifestations of the disease have disappeared, you must complete the course. Otherwise, the disease will return with renewed vigor and stronger medications will have to be selected.

Studies conducted on animals did not reveal a mutagenic or embryotoxic effect of the drug on the intrauterine development of the fetus, however, despite this, Normax tablets are not prescribed for the treatment of pregnant women.

If it is necessary to use the drug while breastfeeding, the issue of stopping lactation should be decided so as not to harm the child, since Norfloxacin is excreted in breast milk.

During the use of Normax tablets, the development of the following side effects in patients was established:

• From the digestive tract - diarrhea, nausea, pain in the right hypochondrium, stomach pain, vomiting, increased salivation, enlarged liver and increased activity of hepatic transminases;
• From the nervous system - headaches, drowsiness, lethargy, increased irritability, feelings of fear and anxiety;
• From the urinary system - inflammation of the kidneys, congestion, dysuria, impaired renal function in severe cases.

Folk remedies, teas

Some doctors will also advise taking herbal infusions and teas in parallel with medications. For example, kidney tea (orosifon stamen) can be included in the complex treatment of prolonged cystitis. Drink kidney tea for at least 4 months with breaks every month for about a week. Kidney tea is made in a water bath and cooled. It is recommended to drink warm kidney tea 2-3 times a day, 100 ml. Diuretic fruit drinks and cranberry or lingonberry tea are also recommended. They also have an antibacterial effect and strengthen the immune system.

Tea with rose hips will also help in treatment; it is a diuretic and is used to strengthen the immune system.

Contraindications

The drug "Normax" is used to treat conditions such as:

• prostatitis;
• inflammatory process in the inner mucous layer of the uterus;
• inflammation of the urethra, cystitis;
• gonorrhea;
• inflammation of the ciliary edge;
• inflammatory kidney disease;
• inflammatory processes in the ear;
• salmonellosis;
• inflammation of the cervix;
• abscess on the edge of the eyelid;
• inflammatory disease of the lacrimal sac of an infectious nature.

Normax for cystitis is strictly prohibited for use in the treatment of pregnant and lactating women. The drug penetrates the placenta into the baby's bloodstream, as well as into the mother's milk. Norfloxacin can cause fetal malformations, the risk especially increases when taking the medicine in the first half of pregnancy.

Children under 18 years of age should also not take Normax, as the drug can cause severe side effects.

Patients with tendon and muscle diseases should choose an analogue for the treatment of cystitis.

Tablets are prohibited for people allergic to Norfloxacin. Hypersensitivity can manifest itself in the form of urticaria, itching, and anaphylactic shock.

Normax or Dancil

Normax is used for any otitis media only in adults. Dancil also works and is used from the first year of life for middle and external ear disease.

When choosing Normax or analogues, it is important to take into account the indications, restrictions on use and the manufacturer. The cost of the medication is important. The drug is not suitable for self-medication; for its use and prescription, you must consult a doctor.

Use in the treatment of cystitis

The medicine is prescribed only by a doctor after examination. The mode of use and dosage are described in detail in the instructions for the drug.

The drug should be taken on an empty stomach, 2 hours after or 1 hour before meals. It is recommended to take the tablet with clean water at room temperature.

In case of acute cystitis that first appears and proceeds without complications, you should take 400 mg twice a day. The course of treatment is from 3 to 5 days.

For frequently recurrent chronic cystitis, the medication is prescribed at a dose of 400 mg twice a day. Duration of treatment is from 4 to 12 weeks.

In case of exacerbations after sexual intercourse, women are recommended to take 200 mg postcoital.

Taking antibiotics does not always lead to a complete cure for the disease.

Infection prevention plays an important role:

• drinking enough water, up to 1-1.5 liters per day,
• women with exacerbation of inflammation after sexual intercourse should urinate and take a Normax tablet,
• stop using spermicides, diaphragm,
• keep your legs and lower back warm,
• dress according to the weather,
• use barrier methods of contraception when contacting a new partner.

Pharmacokinetics

Release forms

Side effect

Contraindications

Use in children

special instructions

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When large doses of the drug are administered orally and patients take the drug for a long time without control, signs of overdose gradually develop, which are expressed in the form of an increase in the above-described side effects, depression of liver function, and confusion.

If such clinical symptoms develop, the patient's stomach is washed, activated carbon or other enterosorbents are administered orally, and symptomatic treatment is given if necessary.

The drug should be prescribed with caution simultaneously with Warfarin or anticoagulants, since interaction with Norfloxacin enhances the effect of the latter, resulting in an increased risk of bleeding.

When used simultaneously with Normax Cyclosporine, the patient experiences an increase in the concentration of the latter in the blood plasma.

Normax tablets are not recommended to be prescribed to patients simultaneously with iron, zinc, magnesium or antacid preparations, since such drug interactions impair the absorption of Norfloxacin and, accordingly, reduce the therapeutic effect.

The drug Normax should be prescribed with particular caution to patients suffering from epilepsy, since during therapy there may be an increase in epileptic seizures and the development of status epilepticus.

Since patients may experience dizziness during treatment with Normax, patients should refrain from driving a car or using equipment that requires increased concentration.

The following drugs are similar in their composition and therapeutic effect to the drug Normax:

• Nolicin tablets;
• Norfloxacin tablets;
• Norbactin tablets;
• Loxon tablets.

Normax tablets are sold from pharmacies with a doctor's prescription. The drug should be kept away from children, avoiding contact of liquid and sunlight with the packaging.

The shelf life of the drug is 5 years from the date of manufacture; after this period, the drug is disposed of.

The average cost of Normax in tablet form in Moscow pharmacies is 155 rubles per package.

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What medications will your doctor recommend you take?

Any inflammation today cannot be cured without taking antibiotics. Previously, people used folk remedies made from medicinal herbs, which relieved inflammation, pain, and increased immunity. Today, it is unlikely that the inflammatory process can be stopped without antibiotics. A woman’s body is weakened, it has little strength to fight pathogenic bacteria, and antibacterial drugs come to its aid.

All antibacterial drugs often have side effects, and broad-spectrum drugs have many of them. Before prescribing antibiotics, the attending physician will definitely conduct a series of studies and tests. Studies showing the body's response to a particular antibiotic are especially important.

Instructions for use: effective dosage for cystitis

Pharmacokinetics

Release forms

Side effect

Contraindications

Use in children

special instructions

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The drug is taken in the morning and evening.

To get rid of cystitis, the drug “Normax” is used in the form of tablets. Mostly, specialists prescribe 400 mg of medication to the patient twice a day: morning and evening. Often, treatment does not take more than 3 days, but in exceptional situations, severe disease may require the use of pharmaceuticals for a week.

If the patient already has complications or infections of the urethra in the chronic stage, then the duration of the course of therapy is sometimes about 3 months. The instructions for use of Normax say that the elimination of unpleasant symptoms is observed after the first dose of the medication.

If you take a large dose of the drug, diarrhea may develop.

• headaches;
• attacks of nausea;
• sense of anxiety;
• gagging;
• diarrhea;
• vertigo.

Special instructions and interactions with other medications

Doctors draw patients’ attention to the fact that during the treatment of cystitis it is important to drink at least 2 liters of purified water daily. In addition, it is important for patients not to forget that Normax increases the rate at which blood clotting starts. The instructions for use of the product note that throughout the entire course of therapy, people should avoid being in direct sunlight. It is important to take special care when driving vehicles and heavy machinery that require increased concentration and speed of reaction. The described medication is not recommended to be taken in combination with Warfarin, since Normax enhances its effect, aimed at blocking the synthesis of blood clotting factors in the liver. When used together with Cyclosporine, it is important to consider that Normax provokes an increase in the accumulation of the latter in the blood.

Side effect

The medication has many side effects, although the frequency of their development is low. If any undesirable symptoms appear, you should contact your doctor to decide whether to continue treatment or change the drug.

The following side effects are identified:

• nausea, vomiting, diarrhea or constipation, loss of appetite,
• headaches, dizziness, sleep disturbances,
• tendinitis, bursitis, swelling of the extremities, exacerbation of myasthenia gravis,
• anemia, agranulocytosis,
• candidiasis.

A side effect of the drug may be fainting.

• pain in the gastrointestinal tract;
• appetite disorders;
• bleeding from the urethra;
• stool disorders;
• attacks of nausea;
• gagging;
• sleep disturbance;
• metallic taste in the mouth;
• increased creatinine levels in the blood;
• itching and burning of the skin;
• fainting;
• swelling;
• pemphigus;
• excess salts in the body;
• decreased blood pressure;
• heart rhythm disturbance;
• thrush;
• hallucinations;
• visual impairment.

Reviews

Pharmacokinetics

Release forms

Side effect

Contraindications

Use in children

special instructions

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On the Internet, the drug Normax for cystitis has good reviews, which is due to the effectiveness of the drug against infectious pathogens.

Oksana, 28 years old, Volgograd. I never had cystitis before my wedding night. Subsequently, this misfortune constantly haunted me until my husband and I started planning a child. It turned out that all my problems were from using a condom. For six months before conception, all 9 months of pregnancy, a year of breastfeeding and a year of taking oral contraceptives, I forgot what cystitis was.

But then problems with the veins began, I had to quit COCs and return to condoms, then the disease returned. Now, on the advice of a competent urologist, I urinate after sex and take a Normax tablet. The symptoms hardly bother me, I think, thanks to the antibiotic.

Natasha, 24 years old, Krasnoyarsk. I myself am a doctor, I’m writing a review because I don’t want anyone to repeat my mistakes and develop chronic inflammation. Until the age of 22, there were never any symptoms of the disease. Then I went to work in surgery and began to spend a lot of time in the operating room. And in the summer there is a fairly powerful air conditioner, which blew into my lower back, which was sweating under a surgical suit. Then I realized what cystitis is.

Treatment was needed urgently, since lengthy operations did not allow me to run to the toilet on demand. I took Normax, but only for 2 days, I stopped as soon as the symptoms disappeared. Then I was blown away again and then the inflammation broke out in full force, blood appeared in the urine. I went to the hospital as a patient and was treated with Normax for 2 weeks, but I couldn’t completely get rid of the inflammation, relapses happen, but they are rare. I regret that I didn’t receive treatment as expected right away!

Sergey, 55 years old, Ufa. I have been diagnosed with kidney stones for about 10 years now; they are small and I have not received any treatment. Apparently, there are metabolic disorders, because stones began to form in the bladder. At the same time, pain, cramping, and frequent urination began to bother me. With these complaints, I went to a therapist, who sent me for a urine test and an ultrasound of the bladder. The diagnosis was acute cystitis.

Treatment – ​​Normax, 1 tablet twice a day for a week, plus herbal drops for 3 months. I felt better after the first dose of antibiotic, although a relapse occurred 2 months after therapy, because, as the doctor explained to me, stones cause inflammation. Now I’m thinking about surgery, but for now I’m saving myself with Normax, a good drug.

Taisiya, 34 years old, Tyumen. Somehow I felt a pain in my lower abdomen, acute pain, frequent urges, stinging, burning. I didn’t even think that it could be cystitis, although my mother and sister had this problem for a long time. I barely made it from work to the pharmacy and asked the pharmacist to advise me on what I could drink for my stomach pain and frequent cravings. She began to list painkillers, to which the woman standing in line said that it was my cystitis and I needed to buy Norfloxacin.

I was then ready to buy and drink anything, but the pharmacy had an Indian equivalent - Normax. The pain subsided within 30 minutes after taking the pill, and by the evening it was completely gone. The next day I went to the clinic, where the diagnosis was confirmed and I was told to take an antibiotic for 5 days. I am so grateful to that woman for the correctly prescribed treatment, now I myself advise my friends to treat cystitis correctly!

Gentle method of treatment - herbal medicines

If there is no fever or unbearable pain, then you can try to overcome cystitis with herbal remedies. They also turn out to be very effective in combination with synthetic antibiotics. These include:

• Cyston. Over 10 varieties of medicinal plant extracts are “hidden” in one tablet. They produce a diuretic and antimicrobial effect. Helps reduce inflammation in the urinary organs. The cost of the herbal medicine is approximately 430 rubles;
• Monurel (cranberry juice) is a very popular remedy. According to healers, cranberry is a unique natural antibiotic. If a woman drinks only 300 ml of fruit drink per day, she will protect herself from cystitis and speed up recovery. Monurel tablets should be taken for a long period. They cost from 450 to 500 rubles;
• Canephron. Also a well-known drug. It includes a combination of medicinal herbs (rosemary, lovage, centaury). It is produced both in dragees and in the form of a solution. Reduces pain, relieves inflammation. Sold for 300-350 rubles;
• Paste Phytolysin. This hydroalcoholic extract has proven itself as a reliable assistant in eliminating cystitis. Contains a mixture of pine, orange, sage oils. It is a safe antispasmodic and has a diuretic effect. You can buy it at the pharmacy for 300-350 rubles.

Many people are so used to cystitis that they consider this problem to be nonsense. In fact, all that pills for cystitis in women can provide is quick treatment, elimination of symptoms, but not the underlying causes of the disease. To avoid bladder inflammation again and again, antibiotics alone are not enough. To exclude relapses, a full examination and proper treatment are necessary. And, of course, you need to follow the “golden rules” that caring mothers always instill in their daughters: don’t freeze, don’t tolerate it, and go to the gynecologist regularly.

Storage conditions

You will need to store the pharmaceutical remedy for cystitis in a room that is protected from children, animals and direct sunlight. The temperature in such a room should not exceed 25 degrees Celsius and decrease to 10 degrees. The shelf life of the medicine is 2 years from the date of its release, the date of which is indicated on the packaging. After this time, the use of the medication is strictly prohibited, so as not to provoke the development of negative reactions.

Rules for medical procedures

In addition to drug therapy, it is recommended to carry out treatment at home using natural ingredients that have antimicrobial and antiseptic properties:

1. Regular baking soda is a great remedy for itching. After dissolving it in boiled water, you need to wash your genitals with the solution.
2. A solution of calendula, when douched, will help get rid of pathogenic microflora.
3. Onions and garlic are antiseptics. The juice of these root vegetables with a small addition of aloe is used to moisten vaginal tampons.