Ciprolet and Ciprofloxacin: the difference, what to choose for effective treatment

When prescribing an antibiotic to treat a bacterial infection, the doctor usually indicates its generally accepted designation in the prescription. This so-called INN (international nonproprietary name) is not tied to a specific manufacturer, of which there are now many. In the pharmacy, the same antibiotic is often available under different brand names from imported or domestic companies, as is the case with ciprofloxacin and Tsiprolet. Ultimately, either the pharmacist or the consumer himself will have to decide what is best to choose. Let's look at their differences.

There are contraindications, use after consulting your doctor

Which drug is more effective?

Considering the fact that the same chemical substance is used in the manufacture of the described drugs, it makes no sense to compare the composition of the drugs. Fluoroquinolones are prescribed in cases where bacteriological infection is accompanied by an infectious pathology. They have almost the same effect on unfavorable microorganisms - they stop the processes of cell division and prevent further protein synthesis, which has a good effect on the patient’s condition. Ciprolet and Ciprofloxacin are considered effective drugs that work well in the fight against various pathogens, including:

Chlamydia

chlamydia;
coli;
proteas;
staphylo- and streptococci;
Klebsiella;
enterobacteria;
listeria.

However, the described medications are ineffective when it comes to fighting fungi or Treponema pallidum. The drugs are not toxic, since the active substance is quickly distributed throughout the body, easily entering all types of tissues (including the brain), practically does not interact with blood proteins, and is then completely excreted in the urine.

Tsprofloxacin or ciprolet: which is better and what is the difference (differences in composition, reviews from doctors)

Treatment of diseases that arise due to the activation of bacterial agents always involves the use of antibacterial agents. If indicated, Ciprofloxacin or Tsiprolet are used.

Treatment of diseases that arise due to the activation of bacterial agents is often carried out with the use of Ciprofloxacin or Ciprolet.

Comparison of drugs

Both medications are antibiotics from the fluoroquinolone group. But they have some similarities and differences.

Is it possible to replace Ciprofloxacin with Ciprolet?

Medicines are interchangeable, since they contain the same active substance.

Methods of application

On the Russian market, both drugs are presented in three variations:

tablets – 250 mg and 500 mg;
solution for intravenous administration - 0.2% of the active ingredient per 100 grams of the finished drug;
eye and ear drops – 0.3% of active ingredient per 5 ml.

Depending on the severity of the disease, its degree, the infection that caused the disease, as well as other factors, the doctor selects the necessary course of treatment, which will provide the necessary effect on the body. In addition, the duration of therapeutic measures using the described medications depends on the listed factors.

The greatest effectiveness of these medications is observed when taken orally on an empty stomach, due to which the concentration of the drug in the blood becomes maximum within 1-2 hours.

Ciprofloxacin or Ciprolet: which is better and what is the difference (differences in composition, reviews from doctors)

Ciprofloxacin belongs to the group of fluoroquinolones. The substance is one of the most effective antibacterial agents. Often used in clinical practice, it is produced by manufacturers under different trade names. The drugs Ciprofloxacin and Tsiprolet are drugs in which this substance acts as an active component.

Characteristics of Ciprofloxacin

The drug has an antibacterial effect and has the ability to cause the death of pathogenic microorganisms. Produced by a number of Russian manufacturers. Israeli-made tablets are also available on the pharmaceutical market.

Ciprofloxacin has an antibacterial effect and has the ability to cause the death of pathogenic microorganisms.

The following forms of the drug are available:

tablets (250 and 500 mg);
solution for infusion (200 mg per 100 ml);
drops for eyes and ears (3 mg);
ointment (0.3 g per 100 g).

The active ingredient is ciprofloxacin. It has an inhibitory effect on bacterial DNA gyrase, disrupting the DNA synchronization mechanism and the formation of cellular proteins in microorganisms.

The activity of the drug is manifested against bacteria that are in the stage of rest and reproduction.

Characteristics of Tsiprolet

The medicine is produced by the Indian manufacturer Dr. Reddy's Laboratories Ltd. Implemented in the following forms:

tablets of 250 and 500 mg;
solution for intravenous administration (2 mg per 1 ml);
eye drops (3 mg).

The main substance in the composition is ciprofloxacin. The pharmacological effect completely coincides with the mechanism of action of the previous drug.

Comparison of Ciprofloxacin and Ciprolet

Both drugs are fluoroquinolone antibiotics.

Similarities

When comparing drugs, the main properties do not differ:

They contain the same active ingredient.
The drugs have the same dosage form and dosage options. The treatment regimen and course duration depend on the disease and are calculated individually by the attending physician, taking into account the patient’s clinical picture and medical history.
Mechanism of action. In bacteria, the enzyme gyrase (belongs to the group of topoisomerases) is responsible for the construction of supercoils in the circular DNA molecule. The active ingredient blocks the activity of the enzyme. This leads to stopping the growth of bacteria and their death, stopping the infectious process.
In both cases, the active component is effective against a number of enterobacteria, cellular pathogens, and affects gram-negative and gram-positive environments. The bacteria Ureaplasma urealyticum, Clostridium difficile, and Nocardia asteroides are resistant to the substance. Treponema pallidum and mushrooms are not sensitive to drugs.
Indications for use. Both drugs are prescribed in the treatment of infectious diseases in uncomplicated forms and cases of secondary infection joining a bacterial infection. Indications include infections of the respiratory tract and ENT organs. Medicines are widely used for lesions of the eyeball, diseases of the kidneys and genitourinary system, and pelvic organs. The list of prescriptions includes infections of the digestive system, biliary system, skin, bone and soft tissue. The drugs are used for sepsis and peritonitis.
Medicines have the same list of contraindications for use: pregnancy and breastfeeding, age less than 18 years, individual intolerance. Careful use requires a history of impaired blood circulation and cerebral atherosclerosis, mental disorders, and epilepsy. Treatment requires special monitoring in elderly patients, as well as in the presence of diabetes mellitus and severe liver and kidney failure.
Possible side effects from the cardiovascular and nervous systems, gastrointestinal tract and liver, musculoskeletal system, and hematopoietic system do not differ. External manifestations of an allergic nature are possible.
During the treatment period, the speed of psychomotor reactions and attentiveness may decrease.
Taking medications should be accompanied by sufficient fluid intake to prevent crystalluria.

The pharmacokinetics of both drugs is characterized by rapid absorption in the walls of the gastrointestinal tract.

The similarity of the drugs is also expressed in the features of drug compatibility:

Combination with a number of anti-inflammatory drugs is not recommended due to the risk of seizures.
The effectiveness of the active substance decreases with simultaneous use of antacids, as well as drugs containing calcium, iron and zinc salts.
When interacting with Theophylline, the concentration of the latter substance in the blood may increase.
Concomitant use of drugs containing cyclosporine increases serum creatinine levels.
The active substance of the drugs enhances the effect of warfarin-based drugs.

Both drugs are prescription drugs.

What is the difference?

The drugs are structural analogues. The main difference is in the manufacturer. Ciprofloxacin is produced by several pharmaceutical companies, and the trade name Ciprolet belongs to an Indian company. Due to differences in pricing policies, the cost of medicines is different.

Tsiprolet is not available in the form of an ointment.

Reviews of the drug Tsiprolet: indications and contraindications, reviews, analogues

Which is cheaper?

The approximate cost of Tsiprolet in pharmacies is:

tablets 250 mg (10 pcs.) – 55-60 rubles;
tablets 500 mg (10 pcs.) – 100-120 rubles;
solution 100 ml – 80-90 rubles;
eye drops 5 ml – 50-60 rub.

The average price of Ciprofloxacin tablets is 30-120 rubles, solution – 30-40 rubles. Eye drops cost 20-25 rubles.

What is better Ciprofloxacin or Ciprolet?

Both drugs are equally effective and do not differ in basic parameters. For some patients, the choice of drug may be determined by cost; for others, by country of origin. The possibility of replacing one drug with another should be agreed with the attending physician.

Patient reviews

Antonina, 31 years old, Chelyabinsk: “When treated with Tsiprolet, I do not feel any side symptoms. The drug was prescribed by the attending physician for complications after wisdom tooth removal, cystitis and bronchitis. Does his job well."

Olesya, 42 years old, Moscow: “Ciprofloxacin is an effective drug. Helped quickly cure cystitis. She took it according to the prescribed regimen, continuing therapy even after the symptoms disappeared.

Tablets are low cost. However, taking the drug provoked a disturbance in the intestinal microflora. Pain in the abdomen, flatulence and abnormal bowel movements appeared.

But this side effect is present with any antibiotic treatment.”

Tsiprolet belongs to an Indian company.

Reviews from doctors about Ciprofloxacin and Tsiprolet

Vladislav Borisovich, urologist, Stavropol: “Over many years of use, Ciprofloxacin has established itself as an effective and well-studied remedy.

Patients show predictable and natural positive dynamics during treatment. It copes well with urogenital infections and is effective in the complex treatment of prostatitis.

The disadvantages of the drug include the need to take it 2 times a day and possible complications of a dyspeptic nature.”

Evgeniy Gennadievich, ENT doctor, St. Petersburg: “Tsiprolet has a broad effect on microflora. The drug is more active compared to antibiotics of the penicillin group.

It is necessary to take into account photosensitivity of the skin; during the treatment period, open sunlight should be avoided.

You should follow a diet that excludes caffeine and dairy products, and saturates your diet with foods high in vitamins and minerals.”

Source: https://SayDiabetu.net/lechenie/tradicionnaya-medicina/drygie-lekarstva/ciprofloksacin-ili-ciprole/

Interaction with other tools

Drugs prescribed for diabetes mellitus enhance the effect of the active substance, increasing its concentration in the blood.

Indications

Taking medications is indicated in the presence of infectious and inflammatory processes, which include:

lung abscess, pneumonia;
gonorrhea;
chlamydia;
peritonitis;
sepsis;
cholecystitis, abdominal abscesses, gall bladder suppuration;
salmonellosis, cholera, typhus, dysentery;
inflammation in the oral cavity;
infection of mucous tissues.

In ophthalmology:

conjunctivitis, corneal ulcer;
otitis;
eyeball injuries, etc.

Also, taking Ciprolet and Ciprofloxacin can be of a prophylactic nature after intracavitary operations or when the immune system is weakened after a long illness.

Contraindications for use

Taking antibiotics in the vast majority of cases creates a serious burden on the body, which is why it is necessary to consult a doctor before starting treatment. The use of Ciprolet and Ciprofloxacin is not recommended for the following categories of people:

pregnant and lactating women;
patients with intolerance to the components contained in the drugs;
people suffering from kidney and liver diseases;
patients under 18 years of age;
people with mental disorders.

When using such medications, attention should be paid to the condition of the patient’s kidneys and liver, since these organs are used to remove the active components of Ciprolet or Ciprofloxacin from the body.

Patients suffering from a lack of glucose-6-phosphate dehydrogenase (related to hereditary pathologies), as well as those who have pseudomembrane colitis, should refrain from taking it - the use of these drugs is contraindicated for them. In addition, patients who have cerebral atherosclerosis, as well as convulsions or epileptic seizures, must undergo a thorough examination in the clinic before using the drug.

Antibiotics Ciprolet and Ciprofloxacin: is there a difference or are they the same thing?

Both drugs, Ciprolet and Ciprofloxacin, have the same active ingredient, the name of which coincides with the name of the second drug.

These are antibacterial drugs that belong to the group of fluoroquinolones .

Available in the form of tablets, solutions for intravenous infusion or drops: tablets of 250 and 500 mg ; solution at a concentration of 0.2% , in one bottle of 100 ml ; drops in a concentration of 0.3% , 5 ml - they are used for instillation into the ears and eyes.

The amount of active ingredient and dosage in both medications are the same.

In many ways, these drugs are identical to each other. They are usually used to treat the same infectious diseases caused by pathogenic bacteria.

ontakte

Odnoklassniki

When comparing Ciprofloxacin and Ciprolet, it is not easy to find the differences between them. Both drugs are broad-spectrum antibacterial agents. They are equally effective against pathogens such as:

staphylococci;
streptococci;
enterobacteria;
Klebsiella;
listeria;
coli;
proteas;
chlamydia.

Since both drugs are based on the same active ingredient - ciprofloxacin, there is no point in comparing them by chemical composition. They have an equally destructive effect on microorganisms , disrupting protein synthesis and stopping the process of cell division. Medicines are ineffective against pathogens such as fungi and Treponema pallidum.

For the human body, both drugs do not pose a great danger. The substance quickly distributes in tissues without causing toxic effects . Despite this, we should not forget about possible adverse reactions that can develop under certain conditions and non-compliance with recommendations for the use of products.

Both drugs are based on the same active ingredient, and therefore have the same anti-tuberculosis activity.

Agents from the fluoroquinolone group are indicated for use in cases where infection with mycobacteria is combined with other infectious diseases.

In this regard, they are not used to treat newly diagnosed tuberculosis - this helps prevent the development of resistance in other pathogens.

The only difference between Ciprofloxacin and Ciprolet is the country in which they are produced . The first product is produced in Russia , the second in India . Therefore, prices for these antibiotics may differ. You may have to pay more for an Indian drug.

Difference in contraindications

Tsiprolet is not recommended for the treatment of bacterial inflammatory diseases in pregnant women and during lactation .

Patients with hypersensitivity to the components of the drug should also avoid using it.

The medication is prohibited for use by people with mental illness, kidney and liver pathologies with impaired function of these organs, as well as patients under 18 years of age .

Contraindications to the use of Ciprofloxacin do not differ from those listed above . This drug is based on the effect of the same active substance as Tsiprolet, so it interacts with the patient’s body in the same way.

If they are affected due to any pathology, taking Ciprolet and Ciprofloxacin can significantly worsen the patient’s condition.

Attention! When choosing a drug from the group of fluoroquinolones, first of all, you should pay attention to the condition of the patient’s kidneys and liver . The exchange and elimination of medications is carried out through these organs.

Side effects: Tsiprolet

In the manufacture of this product, special attention is paid to purifying its components from undesirable impurities and strictly observing all production conditions, so its use is tolerated quite easily, unlike most other drugs in this spectrum.

However, the risk of individual intolerance to the components cannot be excluded, which in some cases is manifested by the appearance of one or more side effects, including:

ripples and pain in the eyes;
hallucinations;
increased sensitivity of the skin - especially to sunlight, which results in rashes and irritation;
allergic reactions – skin itching, anaphylactic shock, etc.;
neurological disorders - depression, depressed states, anxiety, tremor;
abnormalities in the functioning of the digestive system - diarrhea, bloating, nausea, vomiting;
disorders of the liver and kidneys;
nightmares, insomnia;
increased sweating;
deviations in the functioning of the senses - touch, smell, taste, color, sound.

Side effects: Ciprofloxacin

Despite the similarity of the drugs, the side effects from taking Ciprofloxacin are somewhat different. As in the case of Tsiprolet, disturbances in the functioning of the nervous system, kidneys and liver, as well as allergic reactions, are possible. But this list is not complete. Taking ciprofloxacin may cause additional problems, including:

disruptions in the functioning of the cardiovascular system;
high or low blood pressure;
decreased functioning of the musculoskeletal system - patients taking Ciprofloxacin for a long time complain of pain in the joints, ligaments and tendons.

Ciprolet is a safer drug, especially for those who have heart problems (for example, patients with hypotension when using Ciprofloxacin become prone to fainting and frequent dizziness).

Deviation from the established treatment course and recommendations of the attending physician, regardless of the drug used, is fraught with the appearance of nausea, vomiting, dizziness, and disorientation in space. If these symptoms are detected, call an ambulance as soon as possible and perform an emergency gastric lavage. In some cases, after hospitalization, patients are prescribed a course of hemodialysis. Such procedures are also accompanied by an increase in fluid intake, including intravenous infusion of water. The consequences can be very serious, so it is recommended to strictly follow the therapeutic course prescribed by a specialist.

Characteristics of tsipromed

Tsipromed is produced in the form of ear and eye drops. The compositions differ in the form of the active component: in eye drops, ciprofloxacin is presented in the form of hydrochloride, and in ear drops - in the form of lactate.

Tsipromed is used to prevent inflammation after injuries or operations.

Auxiliary components of eye drops are:

benzalkonium chloride;
sodium edetate;
lactic acid;
sodium chloride;
sodium hydroxide;
water for injections.

Additional compounds of ear drops that play a supporting role are:

benzalkonium chloride;
propylene glycol;
lactic acid.

Indications for the use of eye drops are:

acute and subacute forms of conjunctivitis;
keratitis;
anterior chamber uveitis;
blepharitis;
dacryocystitis;
prevention of the inflammatory process after injuries or operations.

Ear drops are prescribed for use in the following cases:

with external otitis;
with otitis media;
before and after surgery;
when receiving an ear injury;
tissue damage when removing a foreign body.

When prescribing Tsipromed for treatment, it is necessary to take into account the possible presence of contraindications for the patient, which are:

pregnancy;
breastfeeding period;
children under 1 year of age;
intolerance to fluoroquinolones;
hypersensitivity to one or more components included in the drug.

The drug in the form of ear drops cannot be used by patients under 16 years of age.

During therapy, the patient may experience a whole list of side effects, the most common of which are:

allergic reaction;
nausea;
urge to vomit;
bowel disorders;
headache;
dizziness;
sense of anxiety.

When using eye drops, local adverse reactions may develop, manifested by:

slight burning sensation in the first minute;
sensation of itching or soreness;
redness of the eye;
swelling in the eyelid area;
photophobia;
increased secretion of tear fluid;
feeling as if something was in the eye;
white crystalline precipitate (in the presence of a corneal ulcer);
blurred vision;
keratitis or keratopathy.

If an overdose occurs, the patient develops:

feeling of nausea and vomiting;
diarrhea;
headache;
dizziness;
fainting;
sense of anxiety.

In case of overdose, it is recommended to use symptomatic treatment accompanied by drinking large amounts of fluid. The use of drugs that increase the acidity of urine and prevent the development of crystalluria may be recommended.

The sale of medicines is carried out in pharmacies only after presenting a prescription from the attending physician.

Recommendations and directions for use

To avoid the risk of side effects and for the most productive treatment, the following rules must be observed when taking Ciprolet and Ciprofloxacin:

Closely monitor your body - any changes that begin immediately after taking the drug serve as a signal of intolerance. Ciprofloxacin, like any antibiotic, can harm the intestinal microflora and cause dehydration, so for any, even minor, ailments, you should consult a doctor.
Drawing and sharp pain in the tendons, discomfort when walking are signs that this drug is not suitable for the patient and must be immediately replaced with another drug.
During therapy using the medications described, it is necessary to ensure a constant flow of fluid into the body. Drinking plenty of clean, still water is the most effective way. Taking liquids enriched with vitamins is also welcome.
Ciprolet and Ciprofloxacin have a significant effect on the nervous system and cause a decrease in reaction speed. Therefore, during treatment it is better to stop driving a car and other vehicles, and also minimize exposure to the sun.
Eye drops should never come into contact with the anterior chamber of the eye.
If the drops irritate the mucous membranes and the effect does not go away for a long time, you must choose another drug.
The shelf life of the drops from the moment the bottle is opened is 1 month.
Drop therapy involves avoiding the use of contact lenses.

Reviews

According to reviews from specialists and patients who have used eye drops to treat ENT diseases, the effectiveness of Tsiprolet is many times higher than conventional remedies for the common cold.

Marina, 29 years old, Syzran: “When my baby (5 years old) and I once again went to the doctor instead of kindergarten, we were prescribed Tsiprolet drops. I was surprised that eye drops were prescribed as a treatment for the nose. But we decided to try anyway. It turned out to be quite an effective remedy. True, it does not work immediately. But somehow it passed unnoticed. But the doctor warned that it should not be used as regular drops for any runny nose. Still an antibiotic."

Valentina, 33 years old, Achinsk: “The drops are good. The doctor prescribed them for us for green snot. My daughter (7 years old) was diagnosed with otitis media. But the bottle is terrible. It also needs to be cut to be used. I made a slight mistake and it’s difficult to dose.”

Unlike vasoconstrictor drugs, Tsiprolet drops do not cause dryness in the nose. The reason for this effect is that the active antibacterial drug acts on the causative agent of the disease.

By destroying bacterial cells, ciprofloxacin does not reduce mucus secretion in the nose. Treatment occurs, and not the removal of symptoms of the disease, as happens when using ordinary drops for the common cold.

What to choose

Despite their very similar composition, these drugs cannot be called identical. Various manufacturers and, consequently, the process of manufacturing drugs are factors that greatly influence the effect of the described drugs on the body. Due to fewer side effects, it follows that Ciprolet is safer than Ciprofloxacin. However, this information has not been confirmed using laboratory tests. On the Russian market, Ciprofloxacin is known as an analogue of Ciprolet, which has a lower price, and people often prefer it.

Doctors do not establish a clear boundary between drugs and do not identify any particular differences, relying only on the patient’s medical history and his individual intolerance to drugs. In most cases, the products are interchangeable. However, it is not recommended to use antibiotics on your own - it is better to trust a doctor with the necessary qualifications. He will easily draw up an algorithm for the necessary treatment, taking into account the results of diagnostic measures, which will help determine the likely culprit in the development of a particular disease. Take care of your health and under no circumstances engage in self-medication, which can aggravate an already unpleasant situation.

Is there an alternative?

There are quite a few analogues of Tsiprolet on sale. The instructions for this drug mention that the main active ingredient is ciprofloxacin. It is also present in the medications “Ciprofloxacin” and “Cifran”. Possible substitutes for the product in question also include Basijen, Betaziprol, Ificipro. The choice of drug for replacement must be agreed with the doctor, taking into account which format of use is preferable for a particular patient. For example, if an antibiotic is needed for oral use, possible alternatives to the “Tsiprolet” in question are “Quintor”, “Procipro”, “Tseprova”.

If it is impossible to purchase the drug prescribed by the doctor, you must contact your doctor and explain the reasons why you cannot buy Tsiprolet. The instructions for using analogues contain fairly detailed information about the technical features of the drugs, but it is almost impossible to select the optimal replacement without having a specific education. Sometimes the doctor recommends using Oftocipro ointment or Rocip drops; in other cases, the optimal solution would be Nircip or Tsiprinol.

To some extent, drops for instillation into the ears “Tsipromed”, for the eyes – “Ciprolon”, tablets “Tsiprobid” and “Ecotsifol” are considered a replacement for the described remedy. The tablet versions “Cipropan” and “Cifloxinal” have a good reputation. For injectable administration, the doctor can offer alternatives to the drug in question, marketed under the names “Ciprobay”, “Ciproxil”, “Ciprofloxabol”, “Cifracid”, “Ciprolacare”.