What is intravesical chemotherapy?

Chemical cystitis: what is it?

From the name it follows that the occurrence of chemical cystitis in the body is facilitated by chemicals. Cosmetics for intimate hygiene and drugs against cancer can equally contribute to the occurrence of cystitis.

In medical practice, not only inflammation of the bladder of an infectious nature, called cystitis, occurs. The causes of the occurrence and development of the disease may lie in another area not related to the penetration of microbes into the organ. One of the types of non-infectious cystitis is chemical cystitis. From the name it is already clear that it occurs under the influence of various types of chemicals.

Treatment after chemotherapy: how to restore health

Login Register Make a Woman. Muratova Anna Eduardovna Psychologist, Online consultant. It occurs when doctors accidentally burn a vein with a chemical solution during a procedure.

• After this, strain the broth and drink half a glass three times a day, you can add natural honey.
• Hair usually falls out after chemotherapy.
• If the tumor does not invade the muscle layer of the bladder, you can count on the high effectiveness of organ-preserving surgery.
• Chemotherapy drugs damage the follicles from which hair grows.
• Psychologist, Clinical psychologist, oncologist.

Causes of chemical cystitis

The most common cause of the disease is the side effect of drugs administered to cancer patients as part of chemotherapy: cyclophosphamide, ifosfamide, mitomycin C, doxorubicin, used by intravesical administration, less often - less toxic epirubicin and other drugs.

Many household chemicals can cause bladder damage in people who are sensitive to some of the chemicals in them. Such “culprits” of chemical cystitis may include sprays for feminine intimate hygiene, spermicidal contraceptives for women, etc.

There is also a subgroup of chemical cystitis, such as medicinal or medicinal. The breakdown products of some medications that are excreted in the urine can react negatively with the tissues of the bladder and cause inflammation.

There are known cases where medications such as indomethacin, tiaprofenic acid, diclofenac, ketoprofen, naproxen, piroxicam (anti-inflammatory drugs), the anti-gout drug allopurinol, the common well-known acetylsalicylic acid and other drugs acted as causative agents of drug-induced cystitis.

Naturally, not every patient who takes these drugs as prescribed by a doctor must necessarily receive drug-induced cystitis in addition to his underlying disease. Such cases are quite rare, which makes them difficult to recognize.

Folk remedies for recovery

After a course of chemotherapy, it is important to resume normal kidney function. Particular attention is paid to restoring the ability to reabsorb fluid and nutrients from the ultrafiltrate and preventing infectious inflammatory processes. After chemical exposure, it is difficult to treat the kidneys. First of all, drug therapy is used. Traditional medicine is widely used to restore kidney function.

Healing herbs

For kidney pathologies, plants with nephroprotective activity, which have antioxidant and antihypoxic effects, are used. Herbs help saturate cells with useful substances, provide a protective function to the membrane and provoke accelerated regeneration. To reduce the toxic effects, the following are used: birch leaves, corn silk, tricolor violet, string, etc. Plants of this group have a diuretic and immunostimulating effect.

It is not recommended to take herbs that contain resinous substances, which provoke irritation of the renal parenchyma.

A decoction of birch leaves is considered affordable and effective in the fight against kidney diseases. It should be taken 3 times a day before meals. The daily portion is prepared as follows: add 1 tablespoon of dry leaves to 1 glass of boiled water. The broth is left in a steam bath for 15-20 minutes. Strain and cool before use.

Diet therapy

To reduce the load on the kidneys during chemotherapy, it is recommended to adhere to special dietary rules. It is necessary to limit the consumption of acidic and irritating foods, especially citrus fruits. You should be careful with salty and spicy foods. The consumption of alcoholic beverages is strictly prohibited. It is advisable to increase the amount of vegetables and fats of plant origin.

Symptoms of chemical cystitis

Symptoms of chemical or drug cystitis can copy standard signs for other forms of cystitis, especially characteristic of its acute form. But other manifestations of the disease are also possible, very different, which can easily be confused with the symptoms of other diseases. Patients may complain of pain in the bladder area, difficulty and retention of urination (dysuria).

Men may experience pain inside the penis. Blood may be found in the urine. Cystoscopy of the bladder may show a significant decrease in size, as well as the appearance of scarred areas of the organ. Sometimes erosive changes, swelling or swelling, and in rare cases even tissue necrosis are observed.

The above symptoms may appear during the start of treatment with the drug (in the first two weeks), and, with long-term use of the drug, after several years. New medications come to the pharmaceutical market with enviable frequency.

It is difficult to quickly identify those that can provoke cystitis and add them to a kind of “black list”. You can’t just blame any medicine for this, because patients often take a whole range of different kinds of drugs for years.

Chemotherapy for bladder cancer: types, regimens, courses, consequences, rehabilitation

Content:
1. Can cystitis be due to chemotherapy? Symptoms of chemical damage
2. Consequences of cystitis during chemotherapy

Medicines used to treat cancer are strong toxins that poison the body.

During therapy, the mucous membranes of the gastrointestinal tract and genitourinary system are injured. Wounds and ulcers in the bladder and decreased immunity create the preconditions for infection and further inflammation. Treatment of cystitis after chemotherapy is carried out during rehabilitation measures.

The purpose of the course: to restore the bladder mucosa and return the organ to full functionality.

Features and advantages of chemotherapy in Oncology

Our oncologists-urologists study and adopt advanced foreign experience and international treatment standards. The regimen and dosage are selected for each patient by the attending physician.

The diagnosis, general condition, presence of concomitant diseases, drug effectiveness, tumor response to treatment and individual tolerance, as well as recommendations of related specialists are taken into account.

Already proven domestic and foreign drugs with minimal toxicity are used.

The treatment plan must include maintenance and detoxification therapy. In the future, rehabilitation measures are carried out aimed at restoring organs and systems damaged during chemotherapy. This is especially true for the hematopoietic system, gastrointestinal tract and kidneys, since the majority of side effects are associated with them.

Chemotherapy for bladder cancer in men and women is carried out at the Oncology Center after a thorough examination, study of test results and instrumental studies, and establishment and clarification of the diagnosis. It is possible to contact the center independently or by referral from other medical institutions.

Treatment is carried out on an outpatient basis, in a day hospital, and, if necessary, with round-the-clock monitoring in the inpatient department of oncourology. At the same time, a convenient schedule of visits is drawn up, taking into account the treatment regimen and the wishes of the patient.

Further patient management with regular consultations and follow-up examinations is also suggested.

Could cystitis be due to chemotherapy?

Due to the high probability of developing complications after stopping taking anticancer drugs, examination and preventive treatment of disorders in the genitourinary system are carried out.

Symptoms of chemical damage

Manifestations of cystitis have common characteristics, regardless of the type of inflammation. Separately, there are symptoms characteristic of mucosal damage due to the use of anticancer drugs.

The first signs appear a few days after intravesical, tablet or intravenous chemotherapy, which allows one to suspect the disease, facilitating differential diagnosis. In rare cases, bladder inflammation develops while taking anticancer drugs.

Symptoms indicating cystitis:

During chemotherapy, the bladder mucosa often suffers. If the symptoms described above are observed after the end of treatment or while taking medications, a series of urological tests are prescribed to confirm cystitis. In case of inflammation aggravated by a bacterial factor, PCR and culture results are necessary to determine an effective treatment regimen.

What medications are used to treat chemical cystitis?

Therapy depends on what exactly caused the inflammation. The treatment regimen is prescribed by a urologist or oncologist depending on the manifestations of the disease, the complications present and the catalyst that provoked the disease:

Pain relief is carried out with antispasmodics and analgesics: No-Shpa, Aspirin, Baralgin, etc.

Ceftriaxone and Ciprofloxacin are highly effective drugs with few contraindications.

Treatment of cystitis after chemotherapy is carried out together with the use of general restoratives that restore the functioning of the genitourinary system. To achieve stable remission, you need to strengthen your immune system and restore bladder function.

Treatment of cystitis with antibiotics during chemotherapy is not recommended. During the period of taking anticancer drugs, conservative restraining therapy will be prescribed. The course of antibiotics is postponed until the end of the chemotherapy course. During the period of primary treatment, given the high probability of complications, preventive measures are taken to prevent inflammation of the bladder.

Non-traditional therapy for chemical cystitis

Traditional methods are used to alleviate the symptomatic manifestations of the disease. Alternative medicine recipes help to quickly restore the bladder mucosa, strengthen the local protective functions of the body, and alleviate the course of the disease.

At home you can use the following methods:

Diet - during an exacerbation period, fried, smoked, fatty foods, and canned food are excluded from the diet. Preference is given to vegetables, cereals, fruits and berries. Boiled meat and fish are allowed.

After chemotherapy, you should not warm the bladder to reduce the symptoms of inflammation. Cancer, even in remission, is a direct contraindication to heat therapy. Drinking plenty of fluids, a healthy diet and moderate physical activity are necessary components to achieve stable remission of the disease.

Diagnosis of chemical cystitis

Diagnosis of chemical (drug, medicinal) cystitis is very difficult due to various factors. For example, a patient can take a certain drug for more than ten years without developing cystitis, but somewhere in the twelfth year of using the drug, its negative effect on the bladder occurs.

Consequences of chemical cystitis

The consequences of the disease, as well as its late diagnosis, can be very serious for the patient. There are even known cases of death, very rare, but nevertheless, such facts have been registered.

Therefore, both doctors and patients themselves must be very vigilant in this regard. Exposure to a drug that causes cystitis definitely needs to be stopped, so the doctor needs a detailed study of the medical history and the chronology of taking medications over several years. Self-diagnosis of this type of disease, of course, is out of the question, as well as getting rid of chemical cystitis on your own. Only mandatory contact with a urologist, only strict implementation of his recommendations.